CRCGN014_HEPG2_3H:O21 Gene Set
Genes
34 genes differentially expressed following the CRCGN014_HEPG2_3H:O21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHMP6
|
charged multivesicular body protein 6
|
6.22907
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
5.75746
|
|
MAP7
|
microtubule-associated protein 7
|
4.21847
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
3.83712
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.827
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.73275
|
|
STK10
|
serine/threonine kinase 10
|
3.67206
|
|
STIMATE
|
STIM activating enhancer
|
3.54085
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.52447
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
3.12462
|
|
ZNF589
|
zinc finger protein 589
|
3.0563
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.9242
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.69582
|
|
CYCS
|
cytochrome c, somatic
|
2.49393
|
|
PFKL
|
phosphofructokinase, liver
|
2.335
|
|
CHN1
|
chimerin 1
|
2.19488
|
|
TSSC4
|
tumor suppressing subtransferable candidate 4
|
2.13871
|
|
GPATCH8
|
G patch domain containing 8
|
2.07429
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.20584
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.15935
|
|
CD320
|
CD320 molecule
|
-4.02856
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-3.91647
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-3.73917
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.65336
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-3.49361
|
|
CCNB2
|
cyclin B2
|
-3.34862
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.88268
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.83571
|
|
RAI14
|
retinoic acid induced 14
|
-2.81657
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.57192
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-2.51451
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.26704
|
|
GNAS
|
GNAS complex locus
|
-2.2439
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.06475
|
