| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | vinyl toluene 39.6 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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81 genes differentially expressed following the CRCGN014_HEPG2_3H:O22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CBR3 | carbonyl reductase 3 | 4.68161 |
| ZNF589 | zinc finger protein 589 | 4.51607 |
| E2F2 | E2F transcription factor 2 | 4.49809 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.48625 |
| ADRB2 | adrenoceptor beta 2, surface | 4.26758 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.15745 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.04051 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.80241 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 3.70551 |
| VGLL4 | vestigial-like family member 4 | 3.61147 |
| HOXA10 | homeobox A10 | 3.49768 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 3.38808 |
| KDM5A | lysine (K)-specific demethylase 5A | 3.21484 |
| SIRT3 | sirtuin 3 | 2.99397 |
| GATA3 | GATA binding protein 3 | 2.97943 |
| SKIC8 | SKI8 subunit of superkiller complex | 2.96382 |
| MOK | MOK protein kinase | 2.92028 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 2.91307 |
| PLSCR3 | phospholipid scramblase 3 | 2.87248 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 2.80992 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.65171 |
| SFTPB | surfactant protein B | 2.64569 |
| CCP110 | centriolar coiled coil protein 110kDa | 2.6405 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C | 2.56942 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 | 2.4337 |
| GPC3 | glypican 3 | 2.40065 |
| APOA2 | apolipoprotein A-II | 2.39245 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 2.34795 |
| TFG | TRK-fused gene | 2.3028 |
| SGSH | N-sulfoglucosamine sulfohydrolase | 2.18928 |
| SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 | 2.18695 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | 2.18402 |
| APOA1 | apolipoprotein A-I | 2.07682 |
| SKIC2 | SKI2 subunit of superkiller complex | 2.07574 |
| MFAP2 | microfibrillar-associated protein 2 | 2.06561 |
| SERPINC1 | serpin peptidase inhibitor, clade C (antithrombin), member 1 | 2.05805 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 2.0545 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 2.05231 |
| APOM | apolipoprotein M | 2.04372 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | 2.04347 |
| CHEK2 | checkpoint kinase 2 | 2.04053 |
| PPP4C | protein phosphatase 4, catalytic subunit | 2.02637 |
| MSX1 | msh homeobox 1 | 2.01877 |
| GAMT | guanidinoacetate N-methyltransferase | 2.01475 |
| LARS2 | leucyl-tRNA synthetase 2, mitochondrial | 2.00742 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -9.17705 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -5.15836 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -5.02887 |
| MRPS2 | mitochondrial ribosomal protein S2 | -5.02497 |
| DSG2 | desmoglein 2 | -4.98838 |
| LDHD | lactate dehydrogenase D | -4.53555 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.20146 |
| ADI1 | acireductone dioxygenase 1 | -3.38951 |
| ZNF586 | zinc finger protein 586 | -3.30644 |
| NRIP1 | nuclear receptor interacting protein 1 | -3.25541 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | -3.11422 |
| CHMP4B | charged multivesicular body protein 4B | -3.0589 |
| TXNDC9 | thioredoxin domain containing 9 | -2.91954 |
| LEPROTL1 | leptin receptor overlapping transcript-like 1 | -2.51168 |
| THAP1 | THAP domain containing, apoptosis associated protein 1 | -2.43639 |
| CSK | c-src tyrosine kinase | -2.3898 |
| TBCB | tubulin folding cofactor B | -2.38961 |
| COX6B1 | cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) | -2.29599 |
| MTFR1 | mitochondrial fission regulator 1 | -2.29225 |
| WDR7 | WD repeat domain 7 | -2.25338 |
| TSKU | tsukushi, small leucine rich proteoglycan | -2.24645 |
| SRD5A2 | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) | -2.24117 |
| GBA3 | glucosidase, beta, acid 3 (gene/pseudogene) | -2.18191 |
| SNX11 | sorting nexin 11 | -2.17941 |
| STX8 | syntaxin 8 | -2.13441 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -2.11178 |
| RASAL2 | RAS protein activator like 2 | -2.09875 |
| NTS | neurotensin | -2.09468 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -2.08153 |
| EIF2B3 | eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa | -2.06849 |
| MKKS | McKusick-Kaufman syndrome | -2.05641 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 | -2.05334 |
| MVP | major vault protein | -2.03758 |
| DDRGK1 | DDRGK domain containing 1 | -2.0285 |
| TBC1D31 | TBC1 domain family, member 31 | -2.02495 |
| WDR62 | WD repeat domain 62 | -2.02386 |
