CRCGN014_HEPG2_3H:P02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description withaferin-a 10.0 um perturbation at 3 h in HEPG2 (Carcinogenome)
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Genes

917 genes differentially expressed following the CRCGN014_HEPG2_3H:P02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 10.0
GPER1 G protein-coupled estrogen receptor 1 6.5002
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 6.408
CYCS cytochrome c, somatic 6.38565
AMDHD2 amidohydrolase domain containing 2 6.18525
LCN2 lipocalin 2 6.0805
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 5.8344
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 5.7527
CIAO3 cytosolic iron-sulfur assembly component 3 5.5843
BZW2 basic leucine zipper and W2 domains 2 5.4489
E2F2 E2F transcription factor 2 4.82735
SRC SRC proto-oncogene, non-receptor tyrosine kinase 4.75065
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha 4.71505
PNKP polynucleotide kinase 3'-phosphatase 4.6875
RPP38 ribonuclease P/MRP 38kDa subunit 4.6691
PPARG peroxisome proliferator-activated receptor gamma 4.6639
CXCL2 chemokine (C-X-C motif) ligand 2 4.5066
SFTPB surfactant protein B 4.43963
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 4.36565
PLSCR1 phospholipid scramblase 1 4.18865
KCNK1 potassium channel, two pore domain subfamily K, member 1 4.1598
AXIN1 axin 1 4.06815
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 4.02285
IKZF1 IKAROS family zinc finger 1 (Ikaros) 3.94293
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 3.8875
NR1H2 nuclear receptor subfamily 1, group H, member 2 3.77545
PTK2 protein tyrosine kinase 2 3.7364
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 3.71275
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 3.6297
CORO1A coronin, actin binding protein, 1A 3.6057
MEST mesoderm specific transcript 3.5403
BARX1 BARX homeobox 1 3.5266
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 3.5233
UBQLN2 ubiquilin 2 3.5002
GJA9 gap junction protein, alpha 9, 59kDa 3.4399
LOC122526780 uncharacterized LOC122526780 3.42715
LOC128966586 pepsin A-4-like 3.4223
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 3.4091
GIPR gastric inhibitory polypeptide receptor 3.406
TSPO2 translocator protein 2 3.40155
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 3.38665
RSPH6A radial spoke head 6 homolog A (Chlamydomonas) 3.377
FAAP20 FA core complex associated protein 20 3.3695
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 3.36425
MSRA methionine sulfoxide reductase A 3.3598
FGFBP1 fibroblast growth factor binding protein 1 3.3154
OXCT2 3-oxoacid CoA transferase 2 3.30425
MOK MOK protein kinase 3.2688
SHB Src homology 2 domain containing adaptor protein B 3.25128
CASP10 caspase 10, apoptosis-related cysteine peptidase 3.23856
VENTX VENT homeobox 3.22505
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 3.22295
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 3.1934
NT5DC2 5'-nucleotidase domain containing 2 3.1925
SPTBN5 spectrin, beta, non-erythrocytic 5 3.1923
SLC22A14 solute carrier family 22, member 14 3.18855
DNASE1L2 deoxyribonuclease I-like 2 3.1879
MAP3K10 mitogen-activated protein kinase kinase kinase 10 3.17875
A4GNT alpha-1,4-N-acetylglucosaminyltransferase 3.16105
NKX2-5 NK2 homeobox 5 3.1435
ESRRA estrogen-related receptor alpha 3.11225
SDK2 sidekick cell adhesion molecule 2 3.10015
ADM2 adrenomedullin 2 3.09365
CCL2 chemokine (C-C motif) ligand 2 3.0906
GBX1 gastrulation brain homeobox 1 3.089
MXI1 MAX interactor 1, dimerization protein 3.0864
HHLA1 HERV-H LTR-associating 1 3.075
HOOK2 hook microtubule-tethering protein 2 3.0748
MEF2B myocyte enhancer factor 2B 3.07095
PRDM1 PR domain containing 1, with ZNF domain 3.04745
TLK2 tousled-like kinase 2 3.03965
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa 3.03335
ATP4B ATPase, H+/K+ exchanging, beta polypeptide 3.02595
FUZ fuzzy planar cell polarity protein 3.02265
PITX3 paired-like homeodomain 3 3.0225
SPIN2A spindlin family, member 2A 3.0213
FOXB1 forkhead box B1 3.02045
RASA2 RAS p21 protein activator 2 3.01545
MYBPH myosin binding protein H 3.0098
RARG retinoic acid receptor, gamma 3.00345
HOXB1 homeobox B1 3.0006
CBLIF cobalamin binding intrinsic factor 3.00055
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 2.99833
PDE1B phosphodiesterase 1B, calmodulin-dependent 2.99795
INPP5K inositol polyphosphate-5-phosphatase K 2.97493
P2RX6 purinergic receptor P2X, ligand gated ion channel, 6 2.97058
ZNG1A Zn regulated GTPase metalloprotein activator 1A 2.9697
TCL1B T-cell leukemia/lymphoma 1B 2.9681
GJA3 gap junction protein, alpha 3, 46kDa 2.9677
OPRD1 opioid receptor, delta 1 2.9481
FOLR3 folate receptor 3 (gamma) 2.9454
PRICKLE3 prickle homolog 3 (Drosophila) 2.9446
KLK14 kallikrein-related peptidase 14 2.9418
CREB1 cAMP responsive element binding protein 1 2.93909
NGF nerve growth factor (beta polypeptide) 2.93815
SHARPIN SHANK-associated RH domain interactor 2.93405
DENND2B DENN domain containing 2B 2.9312
MC3R melanocortin 3 receptor 2.93105
TKFC triokinase/FMN cyclase 2.9114
DNAAF8 dynein axonemal assembly factor 8 2.89895
SSTR4 somatostatin receptor 4 2.89585
CHRND cholinergic receptor, nicotinic, delta (muscle) 2.88975
INHA inhibin, alpha 2.88925
RTL8C retrotransposon Gag like 8C 2.88
HSPB1 heat shock 27kDa protein 1 2.868
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 2.86755
PGM5 phosphoglucomutase 5 2.85955
DAGLA diacylglycerol lipase, alpha 2.85765
DOC2B double C2-like domains, beta 2.85635
MUC3B mucin 3B, cell surface associated 2.8549
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 2.85333
OMP olfactory marker protein 2.852
SSTR3 somatostatin receptor 3 2.8498
TSKS testis-specific serine kinase substrate 2.84492
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4 2.8342
LIPF lipase, gastric 2.834
MAGEA8 melanoma antigen family A8 2.8333
CKAP5 cytoskeleton associated protein 5 2.83165
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1 2.83155
S1PR5 sphingosine-1-phosphate receptor 5 2.8262
CAPN11 calpain 11 2.8241
HIC1 hypermethylated in cancer 1 2.81545
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2 2.8037
SLC12A9 solute carrier family 12, member 9 2.7994
CRABP2 cellular retinoic acid binding protein 2 2.79835
TREML2 triggering receptor expressed on myeloid cells-like 2 2.7913
MED25 mediator complex subunit 25 2.79072
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 2.78938
XKR8 XK, Kell blood group complex subunit-related family, member 8 2.7891
PLCH2 phospholipase C, eta 2 2.78825
IDE insulin-degrading enzyme 2.78673
TNNT3 troponin T type 3 (skeletal, fast) 2.7832
TLN2 talin 2 2.77662
CDK19 cyclin-dependent kinase 19 2.77337
FSTL4 follistatin-like 4 2.7722
ACVR2B activin A receptor, type IIB 2.766
OVOL1 ovo-like zinc finger 1 2.76345
PRLH prolactin releasing hormone 2.7559
ZNF154 zinc finger protein 154 2.7556
TEF thyrotrophic embryonic factor 2.75455
GFRA4 GDNF family receptor alpha 4 2.7538
ACTL7A actin-like 7A 2.7527
CPLANE2 ciliogenesis and planar polarity effector complex subunit 2 2.7444
TP53I11 tumor protein p53 inducible protein 11 2.7421
RBP3 retinol binding protein 3, interstitial 2.7393
FAT2 FAT atypical cadherin 2 2.73735
NSD1 nuclear receptor binding SET domain protein 1 2.7351
ACBD4 acyl-CoA binding domain containing 4 2.72595
TBX21 T-box 21 2.7242
MCHR1 melanin-concentrating hormone receptor 1 2.7235
TULP2 tubby like protein 2 2.71655
FRMPD4 FERM and PDZ domain containing 4 2.7107
EMX1 empty spiracles homeobox 1 2.70845
E2F4 E2F transcription factor 4, p107/p130-binding 2.70738
GUCA1B guanylate cyclase activator 1B (retina) 2.70545
RCVRN recoverin 2.70355
SCRT1 scratch family zinc finger 1 2.7013
RTL8A retrotransposon Gag like 8A 2.6988
FSCN2 fascin actin-bundling protein 2, retinal 2.69645
RPS5 ribosomal protein S5 2.695
LSP1 lymphocyte-specific protein 1 2.6946
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 2.69015
DENND2D DENN/MADD domain containing 2D 2.68985
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) 2.6875
DOK3 docking protein 3 2.6852
TRPV5 transient receptor potential cation channel, subfamily V, member 5 2.68225
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 2.6798
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit 2.67765
EMC10 ER membrane protein complex subunit 10 2.6745
RGL4 ral guanine nucleotide dissociation stimulator-like 4 2.6729
CRYGA crystallin, gamma A 2.6676
SIGLEC9 sialic acid binding Ig-like lectin 9 2.66705
MLF2 myeloid leukemia factor 2 2.66435
NEUROG3 neurogenin 3 2.6551
AMELY amelogenin, Y-linked 2.65265
RAX retina and anterior neural fold homeobox 2.65235
ADAM11 ADAM metallopeptidase domain 11 2.6511
YIF1B Yip1 interacting factor homolog B (S. cerevisiae) 2.6502
FOXO3 forkhead box O3 2.64683
SLC7A4 solute carrier family 7, member 4 2.6406
TRIM11 tripartite motif containing 11 2.63785
SSX5 synovial sarcoma, X breakpoint 5 2.63625
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 2.63605
BMP3 bone morphogenetic protein 3 2.63445
CCNF cyclin F 2.6333
NXPH3 neurexophilin 3 2.62745
SOCS2 suppressor of cytokine signaling 2 2.62733
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4 2.62685
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 2.6248
GPR27 G protein-coupled receptor 27 2.62165
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 2.62075
MRLN myoregulin 2.619
KRT32 keratin 32, type I 2.6176
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.6174
FN3K fructosamine 3 kinase 2.6165
HMX1 H6 family homeobox 1 2.6148
SYTL2 synaptotagmin-like 2 2.61325
ERN1 endoplasmic reticulum to nucleus signaling 1 2.6119
FAM246A family with sequence similarity 246 member A 2.61155
AMN amnion associated transmembrane protein 2.61145
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) 2.6084
DOC2A double C2-like domains, alpha 2.60605
GP9 glycoprotein IX (platelet) 2.60445
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 2.6044
DRD5 dopamine receptor D5 2.5978
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 2.5964
NENF neudesin neurotrophic factor 2.59382
CRHR2 corticotropin releasing hormone receptor 2 2.59298
MTNR1B melatonin receptor 1B 2.58905
SCNN1D sodium channel, non voltage gated 1 delta subunit 2.58295
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4 2.58125
CCDC71 coiled-coil domain containing 71 2.5797
KAT6A K(lysine) acetyltransferase 6A 2.5775
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 2.57742
SLC66A3 solute carrier family 66 member 3 2.5749
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 2.5736
DUSP21 dual specificity phosphatase 21 2.57285
ACAD10 acyl-CoA dehydrogenase family, member 10 2.57245
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic 2.5724
PRR5 proline rich 5 (renal) 2.57125
IL25 interleukin 25 2.57075
IFNAR1 interferon (alpha, beta and omega) receptor 1 2.5707
LOC102723996 ICOS ligand 2.56538
PLCE1 phospholipase C, epsilon 1 2.56527
MVD mevalonate (diphospho) decarboxylase 2.56525
FKBP8 FK506 binding protein 8, 38kDa 2.55565
U2AF2 U2 small nuclear RNA auxiliary factor 2 2.5497
FASTK Fas-activated serine/threonine kinase 2.54925
TRAPPC6A trafficking protein particle complex 6A 2.54635
PHKG1 phosphorylase kinase, gamma 1 (muscle) 2.54265
POU6F2 POU class 6 homeobox 2 2.537
ASIC2 acid sensing (proton gated) ion channel 2 2.5366
ALX4 ALX homeobox 4 2.5355
OR10J1 olfactory receptor, family 10, subfamily J, member 1 2.5326
ARSA arylsulfatase A 2.5318
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 2.53175
SHCBP1L SHC SH2-domain binding protein 1-like 2.53145
CRLF2 cytokine receptor-like factor 2 2.5308
TSSK1B testis-specific serine kinase 1B 2.5302
HEYL hes-related family bHLH transcription factor with YRPW motif-like 2.52395
ARL4C ADP-ribosylation factor-like 4C 2.52308
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 2.52307
CCDC86 coiled-coil domain containing 86 2.5157
STYK1 serine/threonine/tyrosine kinase 1 2.51368
TBC1D17 TBC1 domain family, member 17 2.51185
AJAP1 adherens junctions associated protein 1 2.5109
CCIN calicin 2.51085
ANGPT4 angiopoietin 4 2.50915
OR5I1 olfactory receptor, family 5, subfamily I, member 1 2.50775
LOC124906280 uncharacterized LOC124906280 2.5066
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4 2.5058
VCY1B variable charge, Y-linked 1B 2.5037
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 2.50175
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa 2.4992
MYL7 myosin, light chain 7, regulatory 2.49815
MBOAT7 membrane bound O-acyltransferase domain containing 7 2.49808
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 2.49755
GRM2 glutamate receptor, metabotropic 2 2.49665
ZNF446 zinc finger protein 446 2.49385
LGI2 leucine-rich repeat LGI family, member 2 2.48745
PDE12 phosphodiesterase 12 2.48585
REM1 RAS (RAD and GEM)-like GTP-binding 1 2.48585
KAT2A K(lysine) acetyltransferase 2A 2.48525
OPN1MW3 opsin 1, medium wave sensitive 3 2.48515
FOXE3 forkhead box E3 2.4848
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit 2.4838
CARS1 cysteinyl-tRNA synthetase 1 2.48
PCDHGA9 protocadherin gamma subfamily A, 9 2.47955
GKN1 gastrokine 1 2.47875
DRP2 dystrophin related protein 2 2.4763
MEOX2 mesenchyme homeobox 2 2.47415
ATP5F1D ATP synthase F1 subunit delta 2.4741
MUC6 mucin 6, oligomeric mucus/gel-forming 2.47175
RORC RAR-related orphan receptor C 2.4663
SEC31B SEC31 homolog B (S. cerevisiae) 2.4646
ZNF444 zinc finger protein 444 2.464
RAD23A RAD23 homolog A (S. cerevisiae) 2.45828
ADAM30 ADAM metallopeptidase domain 30 2.45685
GPR173 G protein-coupled receptor 173 2.45675
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A 2.44765
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain 2.4459
TPSD1 tryptase delta 1 2.4448
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 2.444
CLDN14 claudin 14 2.44255
PMFBP1 polyamine modulated factor 1 binding protein 1 2.44185
SACK1E scaffolding CK1 anchoring protein E 2.43977
B3GALT5 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 2.43745
KISS1 KiSS-1 metastasis-suppressor 2.4362
DGKQ diacylglycerol kinase, theta 110kDa 2.43425
GALR3 galanin receptor 3 2.4336
OSBPL7 oxysterol binding protein-like 7 2.43205
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 2.4299
WBP2 WW domain binding protein 2 2.42695
TAPT1 transmembrane anterior posterior transformation 1 2.42565
ARID3B AT rich interactive domain 3B (BRIGHT-like) 2.42375
GAS6 growth arrest-specific 6 2.41692
CRYBA4 crystallin, beta A4 2.4167
SCN2A sodium channel, voltage gated, type II alpha subunit 2.4157
OBP2A odorant binding protein 2A 2.414
BCL7A B-cell CLL/lymphoma 7A 2.4104
PFKM phosphofructokinase, muscle 2.4101
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 2.4097
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1 2.4075
PLA2G4B phospholipase A2, group IVB (cytosolic) 2.40357
IKZF4 IKAROS family zinc finger 4 (Eos) 2.40315
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 2.40015
FOXH1 forkhead box H1 2.39785
DNM2 dynamin 2 2.39665
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 2.39235
TREH trehalase (brush-border membrane glycoprotein) 2.38975
NR5A1 nuclear receptor subfamily 5, group A, member 1 2.38785
PITPNM3 PITPNM family member 3 2.38435
PNMA3 paraneoplastic Ma antigen 3 2.38335
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 2.38195
ASCL3 achaete-scute family bHLH transcription factor 3 2.3784
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 2.3777
CLDN17 claudin 17 2.3765
POM121L2 POM121 transmembrane nucleoporin-like 2 2.3742
CDON cell adhesion associated, oncogene regulated 2.37255
FNDC8 fibronectin type III domain containing 8 2.3698
ANGPTL4 angiopoietin-like 4 2.3697
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 2.36915
CHRNE cholinergic receptor, nicotinic, epsilon (muscle) 2.3689
DOT1L DOT1-like histone H3K79 methyltransferase 2.36875
CDK3 cyclin-dependent kinase 3 2.36685
RBMY1J RNA binding motif protein, Y-linked, family 1, member J 2.36625
ZER1 zyg-11 related, cell cycle regulator 2.36312
REX1BD required for excision 1-B domain containing 2.3627
TULP1 tubby like protein 1 2.35905
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) 2.35795
OVOL3 ovo-like zinc finger 3 2.35485
PLD2 phospholipase D2 2.35345
ETV2 ets variant 2 2.3529
ATP8B3 ATPase, aminophospholipid transporter, class I, type 8B, member 3 2.35285
USP29 ubiquitin specific peptidase 29 2.35105
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 2.35065
LMF1 lipase maturation factor 1 2.35005
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 2.34955
BRME1 break repair meiotic recombinase recruitment factor 1 2.3465
NDOR1 NADPH dependent diflavin oxidoreductase 1 2.34605
DKKL1 dickkopf-like 1 2.3436
OGN osteoglycin 2.34255
VAMP7 vesicle-associated membrane protein 7 2.342
DTX2 deltex 2, E3 ubiquitin ligase 2.3419
GJB4 gap junction protein, beta 4, 30.3kDa 2.3403
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 2.33707
PRRG3 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) 2.33685
FOXN1 forkhead box N1 2.3359
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13 2.33325
KLK11 kallikrein-related peptidase 11 2.3321
OR7C2 olfactory receptor, family 7, subfamily C, member 2 2.3302
CATSPERG catsper channel auxiliary subunit gamma 2.32935
PRDM11 PR domain containing 11 2.3266
PRSS50 protease, serine, 50 2.32645
NOTCH3 notch 3 2.32455
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 2.32312
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae) 2.3225
CABP2 calcium binding protein 2 2.31795
ADRA2B adrenoceptor alpha 2B 2.3174
NPY4R2 neuropeptide Y receptor Y4-2 2.31615
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 2.3161
ATP11B ATPase, class VI, type 11B 2.3159
PSD4 pleckstrin and Sec7 domain containing 4 2.31585
MYL4 myosin, light chain 4, alkali; atrial, embryonic 2.31565
ZNF787 zinc finger protein 787 2.3147
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like 2.3137
KLK12 kallikrein-related peptidase 12 2.3129
EFHD2 EF-hand domain family, member D2 2.3129
TXNL4B thioredoxin-like 4B 2.3124
ARHGAP33 Rho GTPase activating protein 33 2.3123
SMG7 SMG7 nonsense mediated mRNA decay factor 2.31127
SIDT1 SID1 transmembrane family, member 1 2.3106
CAMK1D calcium/calmodulin-dependent protein kinase ID 2.30955
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 2.3077
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3 2.30597
ACTL7B actin-like 7B 2.3007
CCKAR cholecystokinin A receptor 2.29955
PCDHA6 protocadherin alpha 6 2.29887
ADTRP androgen-dependent TFPI-regulating protein 2.2976
ICE2 interactor of little elongation complex ELL subunit 2 2.2962
TRIM13 tripartite motif containing 13 2.2957
RPL18 ribosomal protein L18 2.2917
PRR14L proline rich 14-like 2.29165
CLDN15 claudin 15 2.28835
RASAL1 RAS protein activator like 1 (GAP1 like) 2.288
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 2.28705
GALNT8 polypeptide N-acetylgalactosaminyltransferase 8 2.28688
GPR21 G protein-coupled receptor 21 2.28595
ARHGAP35 Rho GTPase activating protein 35 2.28582
JAK3 Janus kinase 3 2.28543
S1PR4 sphingosine-1-phosphate receptor 4 2.28415
TREX2 three prime repair exonuclease 2 2.2804
POU2F1 POU class 2 homeobox 1 2.28005
TNRC6B trinucleotide repeat containing 6B 2.2797
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 2.2788
TSSK2 testis-specific serine kinase 2 2.27845
GPR132 G protein-coupled receptor 132 2.27725
ALKBH4 alkB, alkylation repair homolog 4 (E. coli) 2.2759
GSK3A glycogen synthase kinase 3 alpha 2.27537
NOX5 NADPH oxidase, EF-hand calcium binding domain 5 2.27315
CBR1 carbonyl reductase 1 2.27185
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1 2.27145
GPRC5D G protein-coupled receptor, class C, group 5, member D 2.26975
AQP7 aquaporin 7 2.2695
POU2F2 POU class 2 homeobox 2 2.26932
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 2.2687
IRS4 insulin receptor substrate 4 2.2667
KCNK2 potassium channel, two pore domain subfamily K, member 2 2.26495
PPIL6 peptidylprolyl isomerase (cyclophilin)-like 6 2.2642
BTBD2 BTB (POZ) domain containing 2 2.26405
BTNL3 butyrophilin-like 3 2.2637
CACNG1 calcium channel, voltage-dependent, gamma subunit 1 2.26355
TP73 tumor protein p73 2.26345
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2 2.26035
BMP10 bone morphogenetic protein 10 2.2576
CRTC1 CREB regulated transcription coactivator 1 2.25663
CYTH4 cytohesin 4 2.25592
JADE2 jade family PHD finger 2 2.25472
OR10H2 olfactory receptor, family 10, subfamily H, member 2 2.2527
WIZ widely interspaced zinc finger motifs 2.25218
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 2.2507
ELL elongation factor RNA polymerase II 2.25052
DEF6 differentially expressed in FDCP 6 homolog (mouse) 2.2494
CCDC33 coiled-coil domain containing 33 2.2474
IL36R interleukin 36 receptor 2.24735
TRAPPC3 trafficking protein particle complex 3 2.2448
DUX4 double homeobox 4 2.24425
DHPS deoxyhypusine synthase 2.24267
CHD6 chromodomain helicase DNA binding protein 6 2.24218
RNF216 ring finger protein 216 2.23995
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 2.2392
ATP2A3 ATPase, Ca++ transporting, ubiquitous 2.2388
VDAC3 voltage-dependent anion channel 3 2.23817
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 2.23577
TACR2 tachykinin receptor 2 2.2348
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) 2.23395
ARHGAP32 Rho GTPase activating protein 32 2.23395
ZNF407 zinc finger protein 407 2.23335
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase) 2.23287
RAB3A RAB3A, member RAS oncogene family 2.2292
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18 2.229
PLXNA1 plexin A1 2.22845
TPO thyroid peroxidase 2.2258
TRPM8 transient receptor potential cation channel, subfamily M, member 8 2.22535
LRTM1 leucine-rich repeats and transmembrane domains 1 2.2239
NANOS1 nanos homolog 1 (Drosophila) 2.2235
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 2.2228
DIPK1A divergent protein kinase domain 1A 2.222
CUL7 cullin 7 2.22155
FFAR3 free fatty acid receptor 3 2.221
KANSL3 KAT8 regulatory NSL complex subunit 3 2.221
PCDHGA1 protocadherin gamma subfamily A, 1 2.22065
RANBP3 RAN binding protein 3 2.2205
ARSF arylsulfatase F 2.22045
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 2.21775
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 2.2166
AMBRA1 autophagy/beclin-1 regulator 1 2.21595
RPS19 ribosomal protein S19 2.21595
GSC2 goosecoid homeobox 2 2.21575
SPMAP2 sperm microtubule associated protein 2 2.21415
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 2.214
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.2121
ACRV1 acrosomal vesicle protein 1 2.20931
EPB41 erythrocyte membrane protein band 4.1 2.20713
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 2.2069
RASA3 RAS p21 protein activator 3 2.20592
CHRM3 cholinergic receptor, muscarinic 3 2.20545
TRIM56 tripartite motif containing 56 2.20445
ISOC2 isochorismatase domain containing 2 2.204
CAMK2B calcium/calmodulin-dependent protein kinase II beta 2.2021
TNMD tenomodulin 2.2013
IL9R interleukin 9 receptor 2.20085
PRDM5 PR domain containing 5 2.2
FGF16 fibroblast growth factor 16 2.19965
H1-3 H1.3 linker histone, cluster member 2.19955
ZNF282 zinc finger protein 282 2.19935
NYNRIN NYN domain and retroviral integrase containing 2.1988
CCDC177 coiled-coil domain containing 177 2.19785
GPR31 G protein-coupled receptor 31 2.19745
LINC02210-CRHR1 LINC02210-CRHR1 readthrough 2.19615
NECAB2 N-terminal EF-hand calcium binding protein 2 2.1945
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) 2.1921
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3 2.192
PTTG2 pituitary tumor-transforming 2 2.19145
C5AR2 complement component 5a receptor 2 2.1908
RGS19 regulator of G-protein signaling 19 2.19015
ZNF671 zinc finger protein 671 2.18985
CNOT3 CCR4-NOT transcription complex, subunit 3 2.18937
ADAM18 ADAM metallopeptidase domain 18 2.18625
SPAG7 sperm associated antigen 7 2.1856
CIBAR1 CBY1 interacting BAR domain containing 1 2.18353
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) 2.18255
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 2.18205
CCS copper chaperone for superoxide dismutase 2.1813
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 2.1787
TBX4 T-box 4 2.1764
MC2R melanocortin 2 receptor (adrenocorticotropic hormone) 2.17473
KLK13 kallikrein-related peptidase 13 2.17435
NHERF4 NHERF family PDZ scaffold protein 4 2.17255
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2 2.17045
TMEM223 transmembrane protein 223 2.1692
SNTG2 syntrophin, gamma 2 2.1682
GHSR growth hormone secretagogue receptor 2.16735
PTGDR prostaglandin D2 receptor (DP) 2.1646
CELF3 CUGBP, Elav-like family member 3 2.16447
FKBP6 FK506 binding protein 6, 36kDa 2.16325
CNGB1 cyclic nucleotide gated channel beta 1 2.16267
IFNW1 interferon, omega 1 2.16255
HRK harakiri, BCL2 interacting protein 2.16245
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit 2.15922
STRADA STE20-related kinase adaptor alpha 2.15692
FGF6 fibroblast growth factor 6 2.1563
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2 2.1542
KLF8 Kruppel-like factor 8 2.15295
IL22 interleukin 22 2.1527
OSBP2 oxysterol binding protein 2 2.1522
GUCY2F guanylate cyclase 2F, retinal 2.15135
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 2.1492
PTGDR2 prostaglandin D2 receptor 2 2.14582
PCDHGB5 protocadherin gamma subfamily B, 5 2.1457
RFX1 regulatory factor X, 1 (influences HLA class II expression) 2.1441
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 2.14335
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 2.14275
DAZL deleted in azoospermia-like 2.14255
RPRM reprimo, TP53 dependent G2 arrest mediator candidate 2.1425
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa 2.1404
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 2.13865
LMTK2 lemur tyrosine kinase 2 2.13785
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit 2.1371
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 2.13395
ANKRD36C ankyrin repeat domain 36C 2.1332
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 2.13038
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta 2.1287
ZNRF4 zinc and ring finger 4 2.12785
MDM4 MDM4, p53 regulator 2.12785
COL6A1 collagen, type VI, alpha 1 2.12712
NEU3 sialidase 3 (membrane sialidase) 2.12698
RAB6B RAB6B, member RAS oncogene family 2.12392
PRX periaxin 2.12305
HSPB3 heat shock 27kDa protein 3 2.12215
INPPL1 inositol polyphosphate phosphatase-like 1 2.12185
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 2.12125
UBXN2B UBX domain protein 2B 2.1184
LOC102724023 ES1 protein homolog, mitochondrial 2.11837
BTG2 BTG family, member 2 2.11812
CRYBG2 crystallin beta-gamma domain containing 2 2.11797
GCGR glucagon receptor 2.11795
PGLYRP4 peptidoglycan recognition protein 4 2.117
WNT5B wingless-type MMTV integration site family, member 5B 2.11635
NXPE4 neurexophilin and PC-esterase domain family, member 4 2.11555
ZBTB7B zinc finger and BTB domain containing 7B 2.1145
SCARB1 scavenger receptor class B, member 1 2.11363
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 2.11165
TRPM6 transient receptor potential cation channel, subfamily M, member 6 2.11125
H2AP H2A.P histone 2.11095
ARMCX2 armadillo repeat containing, X-linked 2 2.11055
OR3A1 olfactory receptor, family 3, subfamily A, member 1 2.11025
DCHS2 dachsous cadherin-related 2 2.10895
AMZ2 archaelysin family metallopeptidase 2 2.1085
HMHB1 histocompatibility (minor) HB-1 2.10825
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2 2.1078
CRX cone-rod homeobox 2.10745
CSNK1E casein kinase 1, epsilon 2.10722
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) 2.10718
HEATR6 HEAT repeat containing 6 2.1067
EYA3 EYA transcriptional coactivator and phosphatase 3 2.1062
H3-4 H3.4 histone, cluster member 2.1042
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 2.1036
GRK1 G protein-coupled receptor kinase 1 2.101
PMM2 phosphomannomutase 2 2.1009
CBX2 chromobox homolog 2 2.1007
NUCB1 nucleobindin 1 2.09997
TREM2 triggering receptor expressed on myeloid cells 2 2.0968
PRDM12 PR domain containing 12 2.09525
STAP2 signal transducing adaptor family member 2 2.09465
PRKCG protein kinase C, gamma 2.0941
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 2.09378
GET3 guided entry of tail-anchored proteins factor 3, ATPase 2.0936
EXTL1 exostosin-like glycosyltransferase 1 2.0931
OR10H3 olfactory receptor, family 10, subfamily H, member 3 2.09305
GFRA3 GDNF family receptor alpha 3 2.0926
DROSHA drosha, ribonuclease type III 2.09235
AP3M2 adaptor-related protein complex 3, mu 2 subunit 2.09125
ATXN3L ataxin 3-like 2.09085
PPP2R5B protein phosphatase 2, regulatory subunit B', beta 2.08993
NPAP1 nuclear pore associated protein 1 2.0897
LBX1 ladybird homeobox 1 2.08965
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 2.08795
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 2.08775
HSF4 heat shock transcription factor 4 2.08735
CLDN9 claudin 9 2.0836
SIGLEC8 sialic acid binding Ig-like lectin 8 2.08282
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 2.0823
TRABD TraB domain containing 2.08065
RIC8A RIC8 guanine nucleotide exchange factor A 2.08
ZFP36L2 ZFP36 ring finger protein-like 2 2.07753
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 2.07748
LRRK1 leucine-rich repeat kinase 1 2.07745
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 2.07705
IL36RN interleukin 36 receptor antagonist 2.0752
BCL2L14 BCL2-like 14 (apoptosis facilitator) 2.07305
CRYBB1 crystallin, beta B1 2.07275
PLSCR2 phospholipid scramblase 2 2.0701
IL12B interleukin 12B 2.06895
ACKR5 atypical chemokine receptor 5 2.0668
MAPKBP1 mitogen-activated protein kinase binding protein 1 2.06605
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 2.06585
KCTD7 potassium channel tetramerization domain containing 7 2.0658
MTSS2 MTSS I-BAR domain containing 2 2.06575
AKAP1 A kinase (PRKA) anchor protein 1 2.06444
TRIM10 tripartite motif containing 10 2.06257
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 2.06189
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae) 2.06185
VWA7 von Willebrand factor A domain containing 7 2.0615
CER1 cerberus 1, DAN family BMP antagonist 2.05945
PRKCE protein kinase C, epsilon 2.05925
MTNAP1 mitochondrial nucleoid associated protein 1 2.05885
TLR6 toll-like receptor 6 2.0586
NEUROG1 neurogenin 1 2.05815
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2 2.05745
SGSM3 small G protein signaling modulator 3 2.05613
GRIK3 glutamate receptor, ionotropic, kainate 3 2.0559
APOL1 apolipoprotein L, 1 2.05545
OCM2 oncomodulin 2 2.05485
CCNB1 cyclin B1 2.05425
ERCC4 excision repair cross-complementation group 4 2.0542
GNG13 guanine nucleotide binding protein (G protein), gamma 13 2.05265
AKT2 v-akt murine thymoma viral oncogene homolog 2 2.05218
OSGIN1 oxidative stress induced growth inhibitor 1 2.05195
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like 2.05115
SYNGAP1 synaptic Ras GTPase activating protein 1 2.04932
BEND5 BEN domain containing 5 2.04905
GPR162 G protein-coupled receptor 162 2.0489
MAP3K3 mitogen-activated protein kinase kinase kinase 3 2.0486
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5 2.0475
CLPTM1 cleft lip and palate associated transmembrane protein 1 2.04722
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2.047
PCDHB1 protocadherin beta 1 2.04665
MRPL4 mitochondrial ribosomal protein L4 2.04655
NTN1 netrin 1 2.046
GPC1 glypican 1 2.04375
VEGFD vascular endothelial growth factor D 2.04305
SAMD4B sterile alpha motif domain containing 4B 2.04305
NPFF neuropeptide FF-amide peptide precursor 2.04285
GRID2 glutamate receptor, ionotropic, delta 2 2.04218
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 2.0407
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 2.0403
KLF15 Kruppel-like factor 15 2.04
CIITA class II, major histocompatibility complex, transactivator 2.03977
KRT38 keratin 38, type I 2.03935
LZTS1 leucine zipper, putative tumor suppressor 1 2.03933
CALCR calcitonin receptor 2.0387
PPP1R2C PPP1R2C family member C 2.03835
ITGB1BP2 integrin beta 1 binding protein (melusin) 2 2.03665
H4C7 H4 clustered histone 7 2.0359
LOC128966601 pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial-like 2.03555
ALX3 ALX homeobox 3 2.0336
ASIC4 acid sensing (proton gated) ion channel family member 4 2.0334
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 2.0325
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14 2.03245
AFTPH aftiphilin 2.0321
CDK5RAP2 CDK5 regulatory subunit associated protein 2 2.03195
SRY sex determining region Y 2.031
LMOD1 leiomodin 1 (smooth muscle) 2.03048
OR2S2 olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene) 2.02975
HOXD9 homeobox D9 2.02945
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 2.02935
MBTPS2 membrane-bound transcription factor peptidase, site 2 2.02892
VRK3 vaccinia related kinase 3 2.0288
MAP2K7 mitogen-activated protein kinase kinase 7 2.02835
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 2.02825
HAGH hydroxyacylglutathione hydrolase 2.02775
TMEM109 transmembrane protein 109 2.02715
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 2.0262
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 2.0254
COL19A1 collagen, type XIX, alpha 1 2.02425
TSHZ2 teashirt zinc finger homeobox 2 2.02345
RIOX1 ribosomal oxygenase 1 2.0232
IVL involucrin 2.02215
ARMCX4 armadillo repeat containing, X-linked 4 2.02175
CA4 carbonic anhydrase IV 2.0212
NCR1 natural cytotoxicity triggering receptor 1 2.01965
TNK1 tyrosine kinase, non-receptor, 1 2.0195
KSR1 kinase suppressor of ras 1 2.01945
KMT2D lysine (K)-specific methyltransferase 2D 2.0193
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 2.019
MROH7 maestro heat-like repeat family member 7 2.0182
AANAT aralkylamine N-acetyltransferase 2.018
LDOC1 leucine zipper, down-regulated in cancer 1 2.01715
NEUROD4 neuronal differentiation 4 2.01705
POLR2J3 polymerase (RNA) II (DNA directed) polypeptide J3 2.01695
ZIC3 Zic family member 3 2.01635
TTC23 tetratricopeptide repeat domain 23 2.0147
TP53I3 tumor protein p53 inducible protein 3 2.01465
MIER2 mesoderm induction early response 1, family member 2 2.01372
ZBTB48 zinc finger and BTB domain containing 48 2.01265
ANGPTL2 angiopoietin-like 2 2.01207
GFRA2 GDNF family receptor alpha 2 2.01207
GPRIN1 G protein regulated inducer of neurite outgrowth 1 2.01109
TAS2R4 taste receptor, type 2, member 4 2.01035
DEPDC5 DEP domain containing 5 2.00865
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 2.00865
LIME1 Lck interacting transmembrane adaptor 1 2.0082
SLAMF7 SLAM family member 7 2.00775
CYLC2 cylicin, basic protein of sperm head cytoskeleton 2 2.0075
EHD2 EH-domain containing 2 2.00663
CDK7 cyclin-dependent kinase 7 2.00615
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 2.006
SDC1 syndecan 1 2.00413
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 2.004
PTCD1 pentatricopeptide repeat domain 1 2.0029
FGD1 FYVE, RhoGEF and PH domain containing 1 2.002
TNIP3 TNFAIP3 interacting protein 3 2.0012
TTC22 tetratricopeptide repeat domain 22 2.00035

decreased expression

Symbol Name Standardized Value
PCNA proliferating cell nuclear antigen -10.0
TLCD3A TLC domain containing 3A -7.8567
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -6.8598
SPAG4 sperm associated antigen 4 -6.25085
PRCP prolylcarboxypeptidase (angiotensinase C) -6.1145
TARBP1 TAR (HIV-1) RNA binding protein 1 -5.0975
LBR lamin B receptor -4.9898
TLR4 toll-like receptor 4 -4.98645
SLC35F2 solute carrier family 35, member F2 -4.97145
CIRBP cold inducible RNA binding protein -4.90657
CRYZ crystallin, zeta (quinone reductase) -4.83825
GOLT1B golgi transport 1B -4.8045
CHMP4B charged multivesicular body protein 4B -4.72895
ENOPH1 enolase-phosphatase 1 -4.71175
TSEN2 TSEN2 tRNA splicing endonuclease subunit -4.57085
TM9SF2 transmembrane 9 superfamily member 2 -4.51335
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -4.41507
ADI1 acireductone dioxygenase 1 -4.4032
NGRN neugrin, neurite outgrowth associated -4.33255
ANXA7 annexin A7 -4.2839
EAPP E2F-associated phosphoprotein -4.2257
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -4.16145
COG7 component of oligomeric golgi complex 7 -4.0856
GLOD4 glyoxalase domain containing 4 -3.96685
TXNDC9 thioredoxin domain containing 9 -3.9465
HAT1 histone acetyltransferase 1 -3.8853
SLC25A46 solute carrier family 25, member 46 -3.8106
BLVRA biliverdin reductase A -3.7719
TXLNA taxilin alpha -3.70135
ACOT9 acyl-CoA thioesterase 9 -3.69765
WASHC4 WASH complex subunit 4 -3.69212
CASP7 caspase 7, apoptosis-related cysteine peptidase -3.6046
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -3.59955
NUP93 nucleoporin 93kDa -3.59015
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -3.5589
CASP3 caspase 3, apoptosis-related cysteine peptidase -3.53555
TOMM34 translocase of outer mitochondrial membrane 34 -3.51325
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -3.4877
CAB39 calcium binding protein 39 -3.46655
DSG2 desmoglein 2 -3.46205
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 -3.43162
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -3.425
CD58 CD58 molecule -3.33497
NVL nuclear VCP-like -3.2757
TCEAL4 transcription elongation factor A (SII)-like 4 -3.23535
SKIC2 SKI2 subunit of superkiller complex -3.21185
RGS2 regulator of G-protein signaling 2 -3.1823
USP22 ubiquitin specific peptidase 22 -3.14287
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -3.1317
PIGT phosphatidylinositol glycan anchor biosynthesis, class T -3.0988
ZW10 zw10 kinetochore protein -3.096
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -3.0467
ANXA5 annexin A5 -3.0465
MALT1 MALT1 paracaspase -3.01342
VAT1 vesicle amine transport 1 -2.9459
SEC23A Sec23 homolog A (S. cerevisiae) -2.93245
YAF2 YY1 associated factor 2 -2.8816
MNAT1 MNAT CDK-activating kinase assembly factor 1 -2.864
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) -2.8402
WDR11 WD repeat domain 11 -2.83025
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.82575
CCND3 cyclin D3 -2.8243
DEGS1 delta(4)-desaturase, sphingolipid 1 -2.824
KLHL21 kelch-like family member 21 -2.8034
MFSD1 major facilitator superfamily domain containing 1 -2.7732
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.75215
SNRPB2 small nuclear ribonucleoprotein polypeptide B -2.72805
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -2.71765
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.71585
BBS7 Bardet-Biedl syndrome 7 -2.71485
SMC4 structural maintenance of chromosomes 4 -2.7094
PALB2 partner and localizer of BRCA2 -2.708
DDRGK1 DDRGK domain containing 1 -2.707
BPHL biphenyl hydrolase-like (serine hydrolase) -2.705
PANK2 pantothenate kinase 2 -2.70295
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.7021
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa -2.69345
GTF2H5 general transcription factor IIH, polypeptide 5 -2.6784
SNRPG small nuclear ribonucleoprotein polypeptide G -2.6736
RNASE7 ribonuclease, RNase A family, 7 -2.63935
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.63855
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -2.63855
GCFC2 GC-rich sequence DNA-binding factor 2 -2.61578
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.59873
ZMIZ1 zinc finger, MIZ-type containing 1 -2.5899
CGRRF1 cell growth regulator with ring finger domain 1 -2.5445
BLMH bleomycin hydrolase -2.53685
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -2.51765
PEX3 peroxisomal biogenesis factor 3 -2.51723
TM9SF3 transmembrane 9 superfamily member 3 -2.5072
TMEM11 transmembrane protein 11 -2.5059
GINS4 GINS complex subunit 4 (Sld5 homolog) -2.50105
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -2.49182
DDB2 damage-specific DNA binding protein 2, 48kDa -2.4877
RXYLT1 ribitol xylosyltransferase 1 -2.48187
CHUK conserved helix-loop-helix ubiquitous kinase -2.4783
NUP85 nucleoporin 85kDa -2.4663
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -2.4631
POGLUT2 protein O-glucosyltransferase 2 -2.4627
TRAP1 TNF receptor-associated protein 1 -2.45715
DHRS7B dehydrogenase/reductase (SDR family) member 7B -2.45225
MYL9 myosin, light chain 9, regulatory -2.4361
RPN1 ribophorin I -2.42755
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 -2.41285
NKX2-2 NK2 homeobox 2 -2.41035
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) -2.40905
RBBP4 retinoblastoma binding protein 4 -2.40435
GEMIN2 gem (nuclear organelle) associated protein 2 -2.39943
PECR peroxisomal trans-2-enoyl-CoA reductase -2.37775
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -2.3752
CHEK1 checkpoint kinase 1 -2.37278
HEATR3 HEAT repeat containing 3 -2.3627
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 -2.36105
L2HGDH L-2-hydroxyglutarate dehydrogenase -2.35375
KRT10 keratin 10, type I -2.34365
CAPN7 calpain 7 -2.32595
FAM114A2 family with sequence similarity 114, member A2 -2.3255
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 -2.32545
RPP40 ribonuclease P/MRP 40kDa subunit -2.3243
DCXR dicarbonyl/L-xylulose reductase -2.32395
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -2.32335
SQOR sulfide quinone oxidoreductase -2.3176
CTPS1 CTP synthase 1 -2.31345
ETFB electron-transfer-flavoprotein, beta polypeptide -2.3122
ZNF226 zinc finger protein 226 -2.3093
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -2.3087
MSANTD2 Myb/SANT-like DNA-binding domain containing 2 -2.30605
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -2.29382
TBC1D10C TBC1 domain family, member 10C -2.2915
SETD6 SET domain containing 6 -2.2855
IGFBP7 insulin-like growth factor binding protein 7 -2.26955
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 -2.2635
TMEM47 transmembrane protein 47 -2.25453
DENND5A DENN/MADD domain containing 5A -2.25275
NR2F6 nuclear receptor subfamily 2, group F, member 6 -2.24992
GOLPH3 golgi phosphoprotein 3 (coat-protein) -2.23945
SCAF8 SR-related CTD-associated factor 8 -2.23805
OXA1L oxidase (cytochrome c) assembly 1-like -2.2353
GCC2 GRIP and coiled-coil domain containing 2 -2.2348
GET1 guided entry of tail-anchored proteins factor 1 -2.2304
TCERG1 transcription elongation regulator 1 -2.19895
SHOC2 soc-2 suppressor of clear homolog (C. elegans) -2.1899
LUM lumican -2.1881
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 -2.186
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 -2.1775
IFT52 intraflagellar transport 52 -2.17695
TBC1D16 TBC1 domain family, member 16 -2.17505
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 -2.17275
FGL1 fibrinogen-like 1 -2.16695
DYNLT3 dynein, light chain, Tctex-type 3 -2.1647
TDG thymine-DNA glycosylase -2.16445
EXOSC10 exosome component 10 -2.1644
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -2.1619
IFNGR1 interferon gamma receptor 1 -2.15912
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase -2.15605
WASF3 WAS protein family, member 3 -2.14565
LOC112694756 uncharaterized LOC112694756 -2.14055
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -2.1362
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -2.13425
CYTL1 cytokine-like 1 -2.13325
CRNKL1 crooked neck pre-mRNA splicing factor 1 -2.1305
NNMT nicotinamide N-methyltransferase -2.12873
TFDP1 transcription factor Dp-1 -2.12627
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 -2.12435
PDZD8 PDZ domain containing 8 -2.1195
TMEM231 transmembrane protein 231 -2.1062
CDC37L1 cell division cycle 37-like 1 -2.1062
POLR2G polymerase (RNA) II (DNA directed) polypeptide G -2.1059
IDH3B isocitrate dehydrogenase 3 (NAD+) beta -2.08575
CCNH cyclin H -2.0819
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 -2.0765
SYBU syntabulin (syntaxin-interacting) -2.06795
ARHGAP17 Rho GTPase activating protein 17 -2.0674
NUP153 nucleoporin 153kDa -2.0638
GMDS GDP-mannose 4,6-dehydratase -2.05955
SRP54 signal recognition particle 54kDa -2.05915
SRSF6 serine/arginine-rich splicing factor 6 -2.05515
NOP56 NOP56 ribonucleoprotein -2.05487
PRKDC protein kinase, DNA-activated, catalytic polypeptide -2.04957
BRD1 bromodomain containing 1 -2.04748
PTBP2 polypyrimidine tract binding protein 2 -2.04175
APOE apolipoprotein E -2.0361
TMEM9B TMEM9 domain family, member B -2.03475
MORF4L1 mortality factor 4 like 1 -2.03463
KIFBP kinesin family binding protein -2.0334
TBPL1 TBP-like 1 -2.03235
CST4 cystatin S -2.03215
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -2.0319
PLK1 polo-like kinase 1 -2.0291
TCTN1 tectonic family member 1 -2.0272
PEX10 peroxisomal biogenesis factor 10 -2.02645
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 -2.02605
SRSF2 serine/arginine-rich splicing factor 2 -2.02062
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7 -2.0199
ADGRG2 adhesion G protein-coupled receptor G2 -2.01475
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 -2.01445
NUP54 nucleoporin 54kDa -2.01385
CASP6 caspase 6, apoptosis-related cysteine peptidase -2.01337
SF3A3 splicing factor 3a, subunit 3, 60kDa -2.0124
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -2.00898
GLT8D1 glycosyltransferase 8 domain containing 1 -2.00877
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) -2.00625
DTD1 D-tyrosyl-tRNA deacylase 1 -2.00135