CRCGN014_HEPG2_3H:P09 Gene Set
Genes
49 genes differentially expressed following the CRCGN014_HEPG2_3H:P09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
7.66409
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
4.55935
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
4.31737
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.14334
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.9595
|
|
KIF14
|
kinesin family member 14
|
3.80137
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.3644
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
3.36099
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.31877
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.21436
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.15615
|
|
NOTCH1
|
notch 1
|
3.05551
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.72042
|
|
CHN1
|
chimerin 1
|
2.68712
|
|
NUP133
|
nucleoporin 133kDa
|
2.43534
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
2.39039
|
|
CEP57
|
centrosomal protein 57kDa
|
2.34915
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.32897
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.30082
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
2.23548
|
|
JADE2
|
jade family PHD finger 2
|
2.21201
|
|
MAP7
|
microtubule-associated protein 7
|
2.19307
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.04725
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-7.42233
|
|
DNM1L
|
dynamin 1-like
|
-6.65521
|
|
TLCD3A
|
TLC domain containing 3A
|
-6.00228
|
|
LDHD
|
lactate dehydrogenase D
|
-5.58909
|
|
DNAJC15
|
DnaJ (Hsp40) homolog, subfamily C, member 15
|
-4.24272
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.99276
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.86508
|
|
TLR4
|
toll-like receptor 4
|
-3.77946
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.70137
|
|
CCNB1
|
cyclin B1
|
-2.99985
|
|
WDR7
|
WD repeat domain 7
|
-2.81695
|
|
GNAS
|
GNAS complex locus
|
-2.73668
|
|
SNX11
|
sorting nexin 11
|
-2.45876
|
|
DCK
|
deoxycytidine kinase
|
-2.41918
|
|
HMOX1
|
heme oxygenase 1
|
-2.41877
|
|
ZNF586
|
zinc finger protein 586
|
-2.36848
|
|
NVL
|
nuclear VCP-like
|
-2.22166
|
|
GUK1
|
guanylate kinase 1
|
-2.20335
|
|
MTA1
|
metastasis associated 1
|
-2.18227
|
|
UPK3B
|
uroplakin 3B
|
-2.15235
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-2.10142
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.09967
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.08916
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.07397
|
|
AVEN
|
apoptosis, caspase activation inhibitor
|
-2.05921
|
|
AHNAK2
|
AHNAK nucleoprotein 2
|
-2.02367
|
