CRCGN014_HEPG2_3H:P12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methoxychlor 20.25 um perturbation at 3 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

52 genes differentially expressed following the CRCGN014_HEPG2_3H:P12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 5.79009
DDIT4 DNA-damage-inducible transcript 4 5.61558
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 5.01288
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 4.285
BACE2 beta-site APP-cleaving enzyme 2 3.97175
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.85518
GPER1 G protein-coupled estrogen receptor 1 3.84963
E2F2 E2F transcription factor 2 3.83802
SFTPB surfactant protein B 3.76051
AMDHD2 amidohydrolase domain containing 2 3.71767
GSTZ1 glutathione S-transferase zeta 1 3.62777
STK10 serine/threonine kinase 10 3.18396
CCL2 chemokine (C-C motif) ligand 2 3.10068
HYOU1 hypoxia up-regulated 1 3.06694
MAMLD1 mastermind-like domain containing 1 2.91247
ABHD6 abhydrolase domain containing 6 2.58842
MYLK myosin light chain kinase 2.55015
MNMIP1 manchette microtubule inner protein 1 2.48763
IDE insulin-degrading enzyme 2.43587
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 2.39113
NOTCH1 notch 1 2.38246
DIPK1A divergent protein kinase domain 1A 2.37063
EAPP E2F-associated phosphoprotein 2.31227
RB1 retinoblastoma 1 2.21678
TREM1 triggering receptor expressed on myeloid cells 1 2.19183
RSPH10B2 radial spoke head 10 homolog B2 (Chlamydomonas) 2.13676
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2.11245
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 2.06045
WDTC1 WD and tetratricopeptide repeats 1 2.05602
GPATCH8 G patch domain containing 8 2.04747
RXYLT1 ribitol xylosyltransferase 1 2.02851
KIF20A kinesin family member 20A 2.01345
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 2.00468

decreased expression

Symbol Name Standardized Value
CDC20 cell division cycle 20 -4.04949
CCNB2 cyclin B2 -3.75924
ADI1 acireductone dioxygenase 1 -3.63416
GOLT1B golgi transport 1B -3.61928
DNM1L dynamin 1-like -3.35401
FGFR4 fibroblast growth factor receptor 4 -3.34674
ZMIZ1 zinc finger, MIZ-type containing 1 -2.93579
RHEB Ras homolog enriched in brain -2.85784
BPHL biphenyl hydrolase-like (serine hydrolase) -2.82982
DHRS7 dehydrogenase/reductase (SDR family) member 7 -2.81848
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.5297
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.44351
TCTN1 tectonic family member 1 -2.35997
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.33769
PSRC1 proline/serine-rich coiled-coil 1 -2.3225
CCNB1 cyclin B1 -2.31984
PYROXD1 pyridine nucleotide-disulphide oxidoreductase domain 1 -2.16949
GRWD1 glutamate-rich WD repeat containing 1 -2.05048
THAP11 THAP domain containing 11 -2.00438