CRCGN014_HEPG2_3H:P15 Gene Set
Genes
41 genes differentially expressed following the CRCGN014_HEPG2_3H:P15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHMP6
|
charged multivesicular body protein 6
|
4.8694
|
|
MAP7
|
microtubule-associated protein 7
|
4.80928
|
|
HOXA10
|
homeobox A10
|
3.90965
|
|
JADE2
|
jade family PHD finger 2
|
3.6617
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.60901
|
|
CHEK2
|
checkpoint kinase 2
|
3.29315
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
3.19246
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.16419
|
|
KIFBP
|
kinesin family binding protein
|
3.13451
|
|
SFTPB
|
surfactant protein B
|
2.94865
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.62539
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
2.61158
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
2.57812
|
|
UFM1
|
ubiquitin-fold modifier 1
|
2.38288
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
2.37038
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
2.30201
|
|
PIH1D1
|
PIH1 domain containing 1
|
2.28041
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.2703
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.2513
|
|
HOXA10-HOXA9
|
HOXA10-HOXA9 readthrough
|
2.24544
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.11982
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.06146
|
|
CDC45
|
cell division cycle 45
|
2.01955
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.00872
|
|
GATA2
|
GATA binding protein 2
|
2.00271
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ADI1
|
acireductone dioxygenase 1
|
-7.62172
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-5.55545
|
|
VAT1
|
vesicle amine transport 1
|
-5.31351
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.82129
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-4.62377
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.93626
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-3.87827
|
|
DCK
|
deoxycytidine kinase
|
-3.62044
|
|
TES
|
testin LIM domain protein
|
-3.22726
|
|
COG7
|
component of oligomeric golgi complex 7
|
-2.71703
|
|
EGF
|
epidermal growth factor
|
-2.63299
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-2.38608
|
|
LDHD
|
lactate dehydrogenase D
|
-2.36497
|
|
CCNB2
|
cyclin B2
|
-2.21148
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.0789
|
|
ANKRD6
|
ankyrin repeat domain 6
|
-2.00104
|
