CRCGN014_HEPG2_3H:P16 Gene Set
Genes
47 genes differentially expressed following the CRCGN014_HEPG2_3H:P16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
6.55323
|
|
CCNF
|
cyclin F
|
5.53325
|
|
MYLK
|
myosin light chain kinase
|
3.64582
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.55206
|
|
CYCS
|
cytochrome c, somatic
|
3.24349
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
2.97474
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.90468
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.902
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.7432
|
|
MAP7
|
microtubule-associated protein 7
|
2.65388
|
|
EPHB2
|
EPH receptor B2
|
2.63389
|
|
NFKBIE
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
|
2.56255
|
|
GNAI2
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
|
2.52111
|
|
CSK
|
c-src tyrosine kinase
|
2.46014
|
|
HEBP1
|
heme binding protein 1
|
2.41716
|
|
HOXA10
|
homeobox A10
|
2.41267
|
|
ELAC2
|
elaC ribonuclease Z 2
|
2.22612
|
|
GNA15
|
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
|
2.17971
|
|
WDTC1
|
WD and tetratricopeptide repeats 1
|
2.17901
|
|
GATA3
|
GATA binding protein 3
|
2.16056
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.13596
|
|
ABCA3
|
ATP-binding cassette, sub-family A (ABC1), member 3
|
2.12487
|
|
ISG15
|
ISG15 ubiquitin-like modifier
|
2.0994
|
|
MAP3K4
|
mitogen-activated protein kinase kinase kinase 4
|
2.0458
|
|
STXBP2
|
syntaxin binding protein 2
|
2.03586
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
2.01003
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.49577
|
|
CCNB2
|
cyclin B2
|
-5.72307
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-5.42612
|
|
DNM1L
|
dynamin 1-like
|
-4.03707
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.59908
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-3.58958
|
|
CCDC86
|
coiled-coil domain containing 86
|
-3.47444
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.0396
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.99589
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.65857
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.62525
|
|
GET1
|
guided entry of tail-anchored proteins factor 1
|
-2.51901
|
|
TCEAL4
|
transcription elongation factor A (SII)-like 4
|
-2.49549
|
|
SNX11
|
sorting nexin 11
|
-2.42376
|
|
MYO5A
|
myosin VA (heavy chain 12, myoxin)
|
-2.20301
|
|
NUP93
|
nucleoporin 93kDa
|
-2.19938
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-2.16014
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.13835
|
|
CASC3
|
cancer susceptibility candidate 3
|
-2.11445
|
|
ZNF586
|
zinc finger protein 586
|
-2.09739
|
|
GALE
|
UDP-galactose-4-epimerase
|
-2.03834
|
