CRCGN014_HEPG2_3H:P20 Gene Set
Genes
49 genes differentially expressed following the CRCGN014_HEPG2_3H:P20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
4.79142
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
3.55039
|
|
SYNGAP1
|
synaptic Ras GTPase activating protein 1
|
3.04197
|
|
SFTPB
|
surfactant protein B
|
2.97885
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.93297
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.8803
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.70598
|
|
MAPKAPK2
|
mitogen-activated protein kinase-activated protein kinase 2
|
2.64862
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.46591
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
2.46225
|
|
EGF
|
epidermal growth factor
|
2.35876
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.35694
|
|
CADPS2
|
Ca++-dependent secretion activator 2
|
2.30497
|
|
ACADVL
|
acyl-CoA dehydrogenase, very long chain
|
2.26453
|
|
NUP133
|
nucleoporin 133kDa
|
2.24056
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.09049
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
2.05637
|
|
RAB38
|
RAB38, member RAS oncogene family
|
2.04433
|
|
RALGDS
|
ral guanine nucleotide dissociation stimulator
|
2.042
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
VAT1
|
vesicle amine transport 1
|
-5.64618
|
|
PLK1
|
polo-like kinase 1
|
-5.3468
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
-5.26674
|
|
TLR4
|
toll-like receptor 4
|
-4.37305
|
|
GNAS
|
GNAS complex locus
|
-3.88178
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-3.64459
|
|
SNX11
|
sorting nexin 11
|
-3.58396
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.87691
|
|
ETFB
|
electron-transfer-flavoprotein, beta polypeptide
|
-2.86864
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-2.78866
|
|
CSK
|
c-src tyrosine kinase
|
-2.58195
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.50549
|
|
GAP43
|
growth associated protein 43
|
-2.37663
|
|
DDX50
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
|
-2.32645
|
|
TP53BP2
|
tumor protein p53 binding protein 2
|
-2.30649
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.22777
|
|
LDHD
|
lactate dehydrogenase D
|
-2.21196
|
|
MTCH1
|
mitochondrial carrier 1
|
-2.20184
|
|
SCRG1
|
stimulator of chondrogenesis 1
|
-2.19655
|
|
NNAT
|
neuronatin
|
-2.16442
|
|
AXIN1
|
axin 1
|
-2.15562
|
|
KIFC1
|
kinesin family member C1
|
-2.13351
|
|
RND2
|
Rho family GTPase 2
|
-2.12317
|
|
TIMM10
|
translocase of inner mitochondrial membrane 10 homolog (yeast)
|
-2.12303
|
|
EN1
|
engrailed homeobox 1
|
-2.11212
|
|
ASCC1
|
activating signal cointegrator 1 complex subunit 1
|
-2.07422
|
|
GPM6A
|
glycoprotein M6A
|
-2.0397
|
|
WNT6
|
wingless-type MMTV integration site family, member 6
|
-2.01853
|
|
RPP40
|
ribonuclease P/MRP 40kDa subunit
|
-2.00447
|
|
KCNIP1
|
Kv channel interacting protein 1
|
-2.00304
|
