CRCGN014_HEPG2_3H:P21 Gene Set
Genes
34 genes differentially expressed following the CRCGN014_HEPG2_3H:P21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
6.46822
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
3.81978
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.61331
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.54703
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.28482
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.25367
|
|
UBQLN2
|
ubiquilin 2
|
3.09546
|
|
NOTCH1
|
notch 1
|
3.02783
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
2.99862
|
|
HMGCR
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
2.85925
|
|
HOXA10
|
homeobox A10
|
2.80695
|
|
ATP11B
|
ATPase, class VI, type 11B
|
2.69718
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.69594
|
|
STIMATE
|
STIM activating enhancer
|
2.59253
|
|
MKNK1
|
MAP kinase interacting serine/threonine kinase 1
|
2.49506
|
|
SFTPB
|
surfactant protein B
|
2.45417
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
2.41759
|
|
SAA2
|
serum amyloid A2
|
2.25747
|
|
CCNF
|
cyclin F
|
2.12831
|
|
WFS1
|
Wolfram syndrome 1 (wolframin)
|
2.04797
|
|
DENR
|
density-regulated protein
|
2.03266
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-9.01256
|
|
MRPS16
|
mitochondrial ribosomal protein S16
|
-4.13508
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-4.06316
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.98688
|
|
VAT1
|
vesicle amine transport 1
|
-3.43912
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-3.3731
|
|
LDHD
|
lactate dehydrogenase D
|
-3.11867
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.81395
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.76789
|
|
TMEM109
|
transmembrane protein 109
|
-2.58868
|
|
CSK
|
c-src tyrosine kinase
|
-2.51019
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
-2.33887
|
|
CCNH
|
cyclin H
|
-2.29671
|
