| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tolazamide 40.0 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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61 genes differentially expressed following the CRCGN014_HEPG2_3H:P22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CCDC92 | coiled-coil domain containing 92 | 5.69194 |
| CYCS | cytochrome c, somatic | 5.53254 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.07334 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.89714 |
| NOTCH1 | notch 1 | 4.86981 |
| SFTPB | surfactant protein B | 4.57014 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 3.46259 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.27587 |
| DIPK1A | divergent protein kinase domain 1A | 3.18581 |
| LOC122526780 | uncharacterized LOC122526780 | 3.17561 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 3.07061 |
| SQOR | sulfide quinone oxidoreductase | 3.01151 |
| HYOU1 | hypoxia up-regulated 1 | 2.8426 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.82372 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 2.80956 |
| CHN1 | chimerin 1 | 2.7748 |
| STK10 | serine/threonine kinase 10 | 2.6773 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.65228 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.59596 |
| KLHL9 | kelch-like family member 9 | 2.59452 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | 2.57845 |
| BHMT2 | betaine--homocysteine S-methyltransferase 2 | 2.57014 |
| ADRB2 | adrenoceptor beta 2, surface | 2.50015 |
| UFM1 | ubiquitin-fold modifier 1 | 2.4831 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 2.42374 |
| EGF | epidermal growth factor | 2.42046 |
| TRIM22 | tripartite motif containing 22 | 2.38672 |
| STAP2 | signal transducing adaptor family member 2 | 2.29974 |
| PLSCR1 | phospholipid scramblase 1 | 2.2992 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 2.26506 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 2.11929 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 2.07613 |
| PIGB | phosphatidylinositol glycan anchor biosynthesis, class B | 2.06741 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -7.47727 |
| ZNF586 | zinc finger protein 586 | -7.23291 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -7.20702 |
| CCNB2 | cyclin B2 | -7.18764 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -5.53113 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -4.82263 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -4.30182 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | -3.468 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -3.1958 |
| VDAC1 | voltage-dependent anion channel 1 | -2.92655 |
| NVL | nuclear VCP-like | -2.92041 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -2.87882 |
| PRPF4 | pre-mRNA processing factor 4 | -2.68635 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.61425 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -2.57193 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -2.32684 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -2.30948 |
| LMX1B | LIM homeobox transcription factor 1, beta | -2.21467 |
| SFXN3 | sideroflexin 3 | -2.13684 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | -2.13592 |
| MRPL37 | mitochondrial ribosomal protein L37 | -2.13236 |
| CMC2 | C-x(9)-C motif containing 2 | -2.12952 |
| SLC2A14 | solute carrier family 2 (facilitated glucose transporter), member 14 | -2.12256 |
| UTF1 | undifferentiated embryonic cell transcription factor 1 | -2.09503 |
| JOSD1 | Josephin domain containing 1 | -2.04575 |
| COQ6 | coenzyme Q6 monooxygenase | -2.04238 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -2.01471 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | -2.01172 |
