CRCGN015_HEPG2_48H:A08 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description potassium 1h-indol-3-yl sulfate 34.76 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

398 genes differentially expressed following the CRCGN015_HEPG2_48H:A08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
VAT1 vesicle amine transport 1 5.51941
SQOR sulfide quinone oxidoreductase 4.67967
CEMIP2 cell migration inducing hyaluronidase 2 4.39556
INPP1 inositol polyphosphate-1-phosphatase 4.24862
PPARG peroxisome proliferator-activated receptor gamma 4.14668
ZFP36 ZFP36 ring finger protein 4.14086
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 3.97997
RAP1GAP RAP1 GTPase activating protein 3.92291
FHL2 four and a half LIM domains 2 3.8597
HMOX1 heme oxygenase 1 3.79654
CDPF1 cysteine-rich, DPF motif domain containing 1 3.68449
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 3.61782
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 3.55648
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 3.50135
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 3.48366
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 3.42354
ALAS1 5'-aminolevulinate synthase 1 3.40094
CYTH1 cytohesin 1 3.38054
TXNRD1 thioredoxin reductase 1 3.37458
VWF von Willebrand factor 3.32907
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 3.2097
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 3.16481
SQSTM1 sequestosome 1 3.10892
TP53I3 tumor protein p53 inducible protein 3 3.1065
PDCD6IP programmed cell death 6 interacting protein 3.08584
ARHGAP12 Rho GTPase activating protein 12 3.08391
FABP4 fatty acid binding protein 4, adipocyte 3.03685
ZMIZ1 zinc finger, MIZ-type containing 1 3.03395
GBE1 glucan (1,4-alpha-), branching enzyme 1 3.00284
TCN2 transcobalamin II 2.94443
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 2.94098
MVP major vault protein 2.93637
LOC102724023 ES1 protein homolog, mitochondrial 2.8568
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 2.85213
SH3GLB1 SH3-domain GRB2-like endophilin B1 2.84142
BMP4 bone morphogenetic protein 4 2.82841
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 2.81632
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2.81507
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 2.81365
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10 2.77737
MAST2 microtubule associated serine/threonine kinase 2 2.76771
PNPLA6 patatin-like phospholipase domain containing 6 2.75141
DOCK1 dedicator of cytokinesis 1 2.74933
STAP2 signal transducing adaptor family member 2 2.7234
CDH5 cadherin 5, type 2 (vascular endothelium) 2.68904
CCL14 chemokine (C-C motif) ligand 14 2.67907
RSU1 Ras suppressor protein 1 2.65604
KCTD9 potassium channel tetramerization domain containing 9 2.6317
DHRS7 dehydrogenase/reductase (SDR family) member 7 2.63128
ACVR1 activin A receptor, type I 2.62036
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 2.6135
RALB v-ral simian leukemia viral oncogene homolog B 2.61165
CIB1 calcium and integrin binding 1 (calmyrin) 2.60498
WDR13 WD repeat domain 13 2.60347
MMRN2 multimerin 2 2.59044
USH1C Usher syndrome 1C (autosomal recessive, severe) 2.58148
MGLL monoglyceride lipase 2.56636
WASHC4 WASH complex subunit 4 2.55884
ACOT9 acyl-CoA thioesterase 9 2.55735
DUSP6 dual specificity phosphatase 6 2.50786
TMEM140 transmembrane protein 140 2.50191
PLIN1 perilipin 1 2.50059
SLCO2A1 solute carrier organic anion transporter family, member 2A1 2.49956
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 2.49828
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) 2.49694
LHFPL2 lipoma HMGIC fusion partner-like 2 2.4933
TIMP2 TIMP metallopeptidase inhibitor 2 2.49173
CISD1 CDGSH iron sulfur domain 1 2.47559
RTN4 reticulon 4 2.46966
ETNK1 ethanolamine kinase 1 2.46552
CTSL cathepsin L 2.46531
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 2.43925
UGDH UDP-glucose 6-dehydrogenase 2.42804
GAK cyclin G associated kinase 2.42683
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 2.42358
FSTL3 follistatin-like 3 (secreted glycoprotein) 2.408
SDCBP syndecan binding protein (syntenin) 2.40781
BECN1 beclin 1, autophagy related 2.38931
BLCAP bladder cancer associated protein 2.38855
EMCN endomucin 2.38609
ADM adrenomedullin 2.35079
ANXA4 annexin A4 2.34494
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 2.3425
IQGAP1 IQ motif containing GTPase activating protein 1 2.33468
BCAR3 breast cancer anti-estrogen resistance 3 2.32764
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 2.32684
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G 2.31104
ABLIM3 actin binding LIM protein family, member 3 2.30707
RAB11A RAB11A, member RAS oncogene family 2.30444
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 2.29334
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 2.28954
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 2.28145
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 2.28104
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 2.27988
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 2.26817
UBE2L6 ubiquitin-conjugating enzyme E2L 6 2.26767
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28 2.26032
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 2.25091
SRPX sushi-repeat containing protein, X-linked 2.24456
SOAT1 sterol O-acyltransferase 1 2.24278
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) 2.2278
LPGAT1 lysophosphatidylglycerol acyltransferase 1 2.21544
FAM174B family with sequence similarity 174, member B 2.21359
NANOS3 nanos homolog 3 (Drosophila) 2.2068
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 2.20113
EXOC1 exocyst complex component 1 2.18232
ETFA electron-transfer-flavoprotein, alpha polypeptide 2.18063
EHD4 EH-domain containing 4 2.16586
PECAM1 platelet/endothelial cell adhesion molecule 1 2.16276
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 2.16018
MAPK13 mitogen-activated protein kinase 13 2.16017
PRKCD protein kinase C, delta 2.15528
SCNN1B sodium channel, non voltage gated 1 beta subunit 2.15165
WIPF2 WAS/WASL interacting protein family, member 2 2.1352
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13 2.12956
VEGFC vascular endothelial growth factor C 2.11749
RGS5 regulator of G-protein signaling 5 2.11623
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 2.10566
LZTR1 leucine-zipper-like transcription regulator 1 2.10524
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 2.10426
QSOX1 quiescin Q6 sulfhydryl oxidase 1 2.0933
JCAD junctional cadherin 5 associated 2.09205
SNCG synuclein, gamma (breast cancer-specific protein 1) 2.09042
SORBS3 sorbin and SH3 domain containing 3 2.08197
WIPI1 WD repeat domain, phosphoinositide interacting 1 2.07841
MMRN1 multimerin 1 2.0781
TRIP4 thyroid hormone receptor interactor 4 2.07269
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 2.07018
TM2D3 TM2 domain containing 3 2.05641
STX7 syntaxin 7 2.05338
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 2.05148
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 2.04776
CSRNP2 cysteine-serine-rich nuclear protein 2 2.04648
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.04604
BAMBI BMP and activin membrane-bound inhibitor 2.03927
LAMA5 laminin, alpha 5 2.02242
ABHD4 abhydrolase domain containing 4 2.02137
RIPPLY2-CYB5R4 RIPPLY2-CYB5R4 readthrough 2.01996
GCLM glutamate-cysteine ligase, modifier subunit 2.01646
TM4SF1 transmembrane 4 L six family member 1 2.01492
EPAS1 endothelial PAS domain protein 1 2.00492
IER3 immediate early response 3 2.0039
ASPH aspartate beta-hydroxylase 2.00264

decreased expression

Symbol Name Standardized Value
MCM3 minichromosome maintenance complex component 3 -4.87081
CENPE centromere protein E, 312kDa -4.79509
KIF4A kinesin family member 4A -4.39614
LBR lamin B receptor -4.20651
KIF20A kinesin family member 20A -4.10619
BIRC5 baculoviral IAP repeat containing 5 -3.97142
CCNB2 cyclin B2 -3.87149
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -3.84492
PUF60 poly-U binding splicing factor 60KDa -3.81365
CCNA2 cyclin A2 -3.77222
CDC45 cell division cycle 45 -3.76141
NUSAP1 nucleolar and spindle associated protein 1 -3.71809
CCNB1 cyclin B1 -3.70571
HMGN2 high mobility group nucleosomal binding domain 2 -3.66336
STMN1 stathmin 1 -3.63236
NDC80 NDC80 kinetochore complex component -3.63211
CDK1 cyclin-dependent kinase 1 -3.62151
ASF1B anti-silencing function 1B histone chaperone -3.61989
CXADR coxsackie virus and adenovirus receptor -3.60542
CDC20 cell division cycle 20 -3.60129
TRMT5 tRNA methyltransferase 5 -3.59473
TMEM97 transmembrane protein 97 -3.40619
NCAPG2 non-SMC condensin II complex, subunit G2 -3.40559
FANCC Fanconi anemia, complementation group C -3.38712
TPX2 TPX2, microtubule-associated -3.3682
TOP2A topoisomerase (DNA) II alpha 170kDa -3.35914
AURKB aurora kinase B -3.3518
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 -3.28654
PTTG1 pituitary tumor-transforming 1 -3.27086
RFC3 replication factor C (activator 1) 3, 38kDa -3.26613
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -3.26589
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -3.24895
KIF15 kinesin family member 15 -3.23795
MCM10 minichromosome maintenance complex component 10 -3.18706
DHFR dihydrofolate reductase -3.17401
AUNIP aurora kinase A and ninein interacting protein -3.16481
B4GAT1 beta-1,4-glucuronyltransferase 1 -3.15429
VRK1 vaccinia related kinase 1 -3.11978
CHAF1B chromatin assembly factor 1, subunit B (p60) -3.08134
CDT1 chromatin licensing and DNA replication factor 1 -3.07446
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -3.061
GINS2 GINS complex subunit 2 (Psf2 homolog) -3.05873
PIMREG PICALM interacting mitotic regulator -3.01787
UBE2C ubiquitin-conjugating enzyme E2C -3.00367
MCM7 minichromosome maintenance complex component 7 -2.98919
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.97917
ERCC6L excision repair cross-complementation group 6-like -2.97697
TRIP13 thyroid hormone receptor interactor 13 -2.97584
RACGAP1 Rac GTPase activating protein 1 -2.9359
HMMR hyaluronan-mediated motility receptor (RHAMM) -2.93379
CDC25C cell division cycle 25C -2.92228
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -2.9142
BRCA1 breast cancer 1, early onset -2.89005
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.88586
MKI67 marker of proliferation Ki-67 -2.87612
PSIP1 PC4 and SFRS1 interacting protein 1 -2.86153
KIFC1 kinesin family member C1 -2.84976
PECR peroxisomal trans-2-enoyl-CoA reductase -2.8435
SESN1 sestrin 1 -2.83433
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.80507
VAV3 vav 3 guanine nucleotide exchange factor -2.79205
SCARA3 scavenger receptor class A, member 3 -2.774
CKAP2 cytoskeleton associated protein 2 -2.76977
NUP155 nucleoporin 155kDa -2.76912
NUP85 nucleoporin 85kDa -2.75484
NEK2 NIMA-related kinase 2 -2.75133
CSE1L CSE1 chromosome segregation 1-like (yeast) -2.73746
KLHL26 kelch-like family member 26 -2.73062
S100P S100 calcium binding protein P -2.7262
FRAT2 frequently rearranged in advanced T-cell lymphomas 2 -2.72416
RBMX RNA binding motif protein, X-linked -2.71618
SPOUT1 SPOUT domain containing methyltransferase 1 -2.7134
ZNF510 zinc finger protein 510 -2.70443
OIP5 Opa interacting protein 5 -2.6959
GMEB1 glucocorticoid modulatory element binding protein 1 -2.69424
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -2.68797
FBXO21 F-box protein 21 -2.68069
SPAG5 sperm associated antigen 5 -2.669
SETD6 SET domain containing 6 -2.66898
FEN1 flap structure-specific endonuclease 1 -2.66047
FZD7 frizzled class receptor 7 -2.65582
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein -2.64908
MCM6 minichromosome maintenance complex component 6 -2.6458
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 -2.64559
CDCA8 cell division cycle associated 8 -2.64488
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -2.63517
SPC25 SPC25, NDC80 kinetochore complex component -2.62884
KIF22 kinesin family member 22 -2.62699
FBL fibrillarin -2.62599
CENPU centromere protein U -2.62138
PSRC1 proline/serine-rich coiled-coil 1 -2.6154
PGM1 phosphoglucomutase 1 -2.61301
RFC4 replication factor C (activator 1) 4, 37kDa -2.61011
MATK megakaryocyte-associated tyrosine kinase -2.60984
TTK TTK protein kinase -2.60879
GLO1 glyoxalase I -2.60667
PRC1 protein regulator of cytokinesis 1 -2.60267
CDCA4 cell division cycle associated 4 -2.60214
HAT1 histone acetyltransferase 1 -2.58297
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -2.57753
PLK1 polo-like kinase 1 -2.56982
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -2.56678
SKI SKI proto-oncogene -2.56529
LMNB1 lamin B1 -2.55079
UXT ubiquitously-expressed, prefoldin-like chaperone -2.54592
EXO1 exonuclease 1 -2.53751
H2AX H2A.X variant histone -2.53241
MIS18A MIS18 kinetochore protein A -2.50534
UFM1 ubiquitin-fold modifier 1 -2.50513
MNS1 meiosis-specific nuclear structural 1 -2.49508
DEPDC1 DEP domain containing 1 -2.49046
MMP9 matrix metallopeptidase 9 -2.48295
MGMT O-6-methylguanine-DNA methyltransferase -2.48002
COG7 component of oligomeric golgi complex 7 -2.47752
MCRS1 microspherule protein 1 -2.47562
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.46007
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 -2.45598
RFXAP regulatory factor X-associated protein -2.45497
CENPA centromere protein A -2.45408
IFITM1 interferon induced transmembrane protein 1 -2.44603
KIF11 kinesin family member 11 -2.44503
ZNF26 zinc finger protein 26 -2.44289
BORA bora, aurora kinase A activator -2.43874
FANCG Fanconi anemia, complementation group G -2.43215
DBF4 DBF4 zinc finger -2.41554
ZNF184 zinc finger protein 184 -2.41515
IBSP integrin-binding sialoprotein -2.40244
KIF18B kinesin family member 18B -2.40172
PRKCB protein kinase C, beta -2.38801
HMGB2 high mobility group box 2 -2.38256
CDC23 cell division cycle 23 -2.37999
KDM1A lysine (K)-specific demethylase 1A -2.36947
CDCA3 cell division cycle associated 3 -2.36932
PRMT7 protein arginine methyltransferase 7 -2.36379
PGAP2 post-GPI attachment to proteins 2 -2.35911
CKS1B CDC28 protein kinase regulatory subunit 1B -2.35632
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -2.35564
MSH6 mutS homolog 6 -2.35525
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -2.34829
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 -2.34663
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -2.34394
TDP1 tyrosyl-DNA phosphodiesterase 1 -2.3401
RRM1 ribonucleotide reductase M1 -2.33802
ELOVL6 ELOVL fatty acid elongase 6 -2.33217
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1 -2.33185
COL11A1 collagen, type XI, alpha 1 -2.33045
ZMYM1 zinc finger, MYM-type 1 -2.32482
FBXO5 F-box protein 5 -2.32102
MCM5 minichromosome maintenance complex component 5 -2.31722
NIPBL Nipped-B homolog (Drosophila) -2.31356
IFITM3 interferon induced transmembrane protein 3 -2.30537
HMGB1 high mobility group box 1 -2.30313
RPL36A ribosomal protein L36a -2.30248
PIM2 Pim-2 proto-oncogene, serine/threonine kinase -2.30097
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.28836
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 -2.27951
PUS1 pseudouridylate synthase 1 -2.27643
CENPM centromere protein M -2.27289
CD320 CD320 molecule -2.27272
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -2.27172
RPL35 ribosomal protein L35 -2.2671
POLR1F RNA polymerase I subunit F -2.26394
SUZ12 SUZ12 polycomb repressive complex 2 subunit -2.26036
IPO5 importin 5 -2.25481
RESF1 retroelement silencing factor 1 -2.25417
FRAT1 frequently rearranged in advanced T-cell lymphomas 1 -2.24497
ABT1 activator of basal transcription 1 -2.24319
AKR1D1 aldo-keto reductase family 1, member D1 -2.24221
NEIL3 nei endonuclease VIII-like 3 (E. coli) -2.2409
MMP13 matrix metallopeptidase 13 -2.22676
NELL2 NEL-like 2 (chicken) -2.22354
SDF2L1 stromal cell-derived factor 2-like 1 -2.22348
DHPS deoxyhypusine synthase -2.22051
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa -2.21762
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.21476
ITM2C integral membrane protein 2C -2.21202
C5 complement component 5 -2.20807
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase -2.20783
EXOSC8 exosome component 8 -2.20559
MKS1 Meckel syndrome, type 1 -2.2043
CHL1 cell adhesion molecule L1-like -2.19755
GPHN gephyrin -2.18694
EPHX2 epoxide hydrolase 2, cytoplasmic -2.18609
SET SET nuclear proto-oncogene -2.18586
RRM2 ribonucleotide reductase M2 -2.18478
ZBTB25 zinc finger and BTB domain containing 25 -2.18409
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.17205
NCAPD2 non-SMC condensin I complex, subunit D2 -2.17148
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -2.16824
VCPKMT valosin containing protein lysine (K) methyltransferase -2.16307
DEAF1 DEAF1 transcription factor -2.15835
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -2.15361
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -2.15348
TGIF2 TGFB-induced factor homeobox 2 -2.14005
PAGR1 PAXIP1 associated glutamate-rich protein 1 -2.13773
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 -2.13451
CCNF cyclin F -2.13197
NR2F6 nuclear receptor subfamily 2, group F, member 6 -2.13176
GPAA1 glycosylphosphatidylinositol anchor attachment 1 -2.12997
GGCT gamma-glutamylcyclotransferase -2.1187
TMEM160 transmembrane protein 160 -2.11659
LAX1 lymphocyte transmembrane adaptor 1 -2.11555
GNG7 guanine nucleotide binding protein (G protein), gamma 7 -2.11396
PTGES3 prostaglandin E synthase 3 (cytosolic) -2.11283
HJURP Holliday junction recognition protein -2.11238
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.11227
SLC44A1 solute carrier family 44 (choline transporter), member 1 -2.11226
URI1 URI1, prefoldin-like chaperone -2.11014
TK1 thymidine kinase 1, soluble -2.10994
OARD1 O-acyl-ADP-ribose deacylase 1 -2.10781
MAK16 MAK16 homolog (S. cerevisiae) -2.10504
SLC35H1 solute carrier family 35 member H1 -2.10162
IL11RA interleukin 11 receptor, alpha -2.09049
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 -2.08821
SNRPA small nuclear ribonucleoprotein polypeptide A -2.08601
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 -2.08556
GYG2 glycogenin 2 -2.08078
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 -2.08028
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 -2.07706
CNPY3 canopy FGF signaling regulator 3 -2.07215
WDR70 WD repeat domain 70 -2.07057
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D -2.06277
ARHGAP19 Rho GTPase activating protein 19 -2.05983
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) -2.05666
NRF1 nuclear respiratory factor 1 -2.05652
PURA purine-rich element binding protein A -2.0554
H2AZ2 H2A.Z variant histone 2 -2.04903
ZWINT ZW10 interacting kinetochore protein -2.0462
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -2.04432
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -2.04309
LDLRAP1 low density lipoprotein receptor adaptor protein 1 -2.04255
RFC2 replication factor C (activator 1) 2, 40kDa -2.04071
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -2.03953
EEF2 eukaryotic translation elongation factor 2 -2.03745
IARS1 isoleucyl-tRNA synthetase 1 -2.03706
THEM6 thioesterase superfamily member 6 -2.03062
LRIG3 leucine-rich repeats and immunoglobulin-like domains 3 -2.02683
PROM1 prominin 1 -2.02492
TMEM258 transmembrane protein 258 -2.02403
TMPO thymopoietin -2.0238
PLK4 polo-like kinase 4 -2.02328
SRRM1 serine/arginine repetitive matrix 1 -2.02283
GTPBP4 GTP binding protein 4 -2.02151
FAM168A family with sequence similarity 168, member A -2.02054
BPHL biphenyl hydrolase-like (serine hydrolase) -2.01872
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2 -2.01549
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 -2.01537
BIN2 bridging integrator 2 -2.01274
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa -2.01263
KIF23 kinesin family member 23 -2.0068
PAQR4 progestin and adipoQ receptor family member IV -2.00613
NLRP4 NLR family, pyrin domain containing 4 -2.00536
BARD1 BRCA1 associated RING domain 1 -2.00455
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 -2.00259
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) -2.00058