CRCGN015_HEPG2_48H:A11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description (e)-3h-indol-3-ylidenemethanol 33.95 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

16 genes differentially expressed following the CRCGN015_HEPG2_48H:A11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TBXA2R thromboxane A2 receptor 2.84795
HLA-DRA major histocompatibility complex, class II, DR alpha 2.7006
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 2.70024
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 2.64039
LAGE3 L antigen family, member 3 2.38577
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa 2.03804
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 2.00952
TBPL1 TBP-like 1 2.00702

decreased expression

Symbol Name Standardized Value
RPS4Y1 ribosomal protein S4, Y-linked 1 -5.0
DERA deoxyribose-phosphate aldolase (putative) -4.5174
DUSP6 dual specificity phosphatase 6 -4.15942
INPP1 inositol polyphosphate-1-phosphatase -3.34879
BAZ2B bromodomain adjacent to zinc finger domain, 2B -2.3536
ANXA5 annexin A5 -2.29025
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.07386
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -2.05636