CRCGN015_HEPG2_48H:A12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description (e)-3h-indol-3-ylidenemethanol 11.32 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

16 genes differentially expressed following the CRCGN015_HEPG2_48H:A12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SMIM40 small integral membrane protein 40 6.28813
GATA3 GATA binding protein 3 3.76957
BAD BCL2-associated agonist of cell death 3.31646
WDR46 WD repeat domain 46 3.00695
RNPS1 RNA binding protein S1, serine-rich domain 2.36481
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 2.33744
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) 2.26908
CRELD2 cysteine-rich with EGF-like domains 2 2.08295
PPP4C protein phosphatase 4, catalytic subunit 2.01605

decreased expression

Symbol Name Standardized Value
SNX7 sorting nexin 7 -4.05807
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.74709
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.35644
MT1X metallothionein 1X -2.31077
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -2.10315
RPS4Y1 ribosomal protein S4, Y-linked 1 -2.07193
EYA2 EYA transcriptional coactivator and phosphatase 2 -2.04886