CRCGN015_HEPG2_48H:A16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description shahrm perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

858 genes differentially expressed following the CRCGN015_HEPG2_48H:A16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TRIB3 tribbles pseudokinase 3 6.27269
FHL2 four and a half LIM domains 2 6.07182
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 5.98508
IL4R interleukin 4 receptor 5.01223
NANOS3 nanos homolog 3 (Drosophila) 4.86356
TRIB1 tribbles pseudokinase 1 4.64463
MAPK13 mitogen-activated protein kinase 13 4.39803
STXBP3 syntaxin binding protein 3 4.37844
INPP1 inositol polyphosphate-1-phosphatase 4.32355
SARS1 seryl-tRNA synthetase 1 4.28281
DDIT4 DNA-damage-inducible transcript 4 4.26938
TOMM34 translocase of outer mitochondrial membrane 34 4.22787
ADGRE5 adhesion G protein-coupled receptor E5 4.14924
ZFP36 ZFP36 ring finger protein 3.99163
YARS1 tyrosyl-tRNA synthetase 1 3.96948
IER3 immediate early response 3 3.94963
ACVR1 activin A receptor, type I 3.87299
YIPF4 Yip1 domain family, member 4 3.85068
PNKP polynucleotide kinase 3'-phosphatase 3.84293
CARS1 cysteinyl-tRNA synthetase 1 3.79796
PLEKHJ1 pleckstrin homology domain containing, family J member 1 3.77675
DSG2 desmoglein 2 3.73958
GRB10 growth factor receptor-bound protein 10 3.71574
RTCA RNA 3'-terminal phosphate cyclase 3.67135
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 3.66069
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 3.65257
CTSL cathepsin L 3.65128
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 3.62858
NARS1 asparaginyl-tRNA synthetase 1 3.60706
SQSTM1 sequestosome 1 3.59829
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 3.59296
ERCC1 excision repair cross-complementation group 1 3.51665
KIFBP kinesin family binding protein 3.50174
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 3.49962
VAT1 vesicle amine transport 1 3.43333
C2CD2 C2 calcium-dependent domain containing 2 3.37632
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 3.37628
ASNS asparagine synthetase (glutamine-hydrolyzing) 3.35139
GBA1 glucosylceramidase beta 1 3.3081
G0S2 G0/G1 switch 2 3.30383
LHFPL2 lipoma HMGIC fusion partner-like 2 3.28361
AARS1 alanyl-tRNA synthetase 1 3.26065
SQOR sulfide quinone oxidoreductase 3.22767
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 3.22
GTPBP2 GTP binding protein 2 3.21701
AVEN apoptosis, caspase activation inhibitor 3.21403
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 3.20934
TP53I3 tumor protein p53 inducible protein 3 3.18073
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 3.1658
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) 3.14822
EREG epiregulin 3.14714
PHC2 polyhomeotic homolog 2 (Drosophila) 3.11714
LZTR1 leucine-zipper-like transcription regulator 1 3.07884
CCDC92 coiled-coil domain containing 92 3.07309
GARS1 glycyl-tRNA synthetase 1 3.06815
STX12 syntaxin 12 3.04901
DDRGK1 DDRGK domain containing 1 3.03893
PROCR protein C receptor, endothelial 2.999
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2.99371
MAP7D1 MAP7 domain containing 1 2.99346
ADGRL4 adhesion G protein-coupled receptor L4 2.97261
RPL39L ribosomal protein L39-like 2.96367
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2.96296
PRSS8 protease, serine, 8 2.95211
TM2D1 TM2 domain containing 1 2.93774
SH2B3 SH2B adaptor protein 3 2.9087
STX1A syntaxin 1A (brain) 2.90202
MMRN2 multimerin 2 2.89132
GPR183 G protein-coupled receptor 183 2.88935
SCG5 secretogranin V 2.88127
LRRC42 leucine rich repeat containing 42 2.87397
SFXN3 sideroflexin 3 2.87387
BECN1 beclin 1, autophagy related 2.8714
ACOT9 acyl-CoA thioesterase 9 2.86
PLK3 polo-like kinase 3 2.85657
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 2.85499
ADGRF5 adhesion G protein-coupled receptor F5 2.85397
KIF5C kinesin family member 5C 2.85189
RRAGD Ras-related GTP binding D 2.84611
MOCS1 molybdenum cofactor synthesis 1 2.83591
CLDN8 claudin 8 2.83528
GREM1 gremlin 1, DAN family BMP antagonist 2.83248
PWP2 PWP2 periodic tryptophan protein homolog (yeast) 2.82912
LIN37 lin-37 DREAM MuvB core complex component 2.82419
RALB v-ral simian leukemia viral oncogene homolog B 2.82132
BLVRA biliverdin reductase A 2.81991
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 2.79553
CSRNP2 cysteine-serine-rich nuclear protein 2 2.78984
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 2.78719
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 2.78573
FRY furry homolog (Drosophila) 2.78412
LRRC8B leucine rich repeat containing 8 family, member B 2.77617
STIMATE STIM activating enhancer 2.75932
IL15RA interleukin 15 receptor, alpha 2.74849
ELOVL1 ELOVL fatty acid elongase 1 2.74506
PFKP phosphofructokinase, platelet 2.74439
KCMF1 potassium channel modulatory factor 1 2.74333
C5AR1 complement component 5a receptor 1 2.73723
NOD2 nucleotide-binding oligomerization domain containing 2 2.73571
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 2.72923
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 2.7244
IFRD1 interferon-related developmental regulator 1 2.7216
SOCS2 suppressor of cytokine signaling 2 2.71046
STX4 syntaxin 4 2.6998
OSGIN2 oxidative stress induced growth inhibitor family member 2 2.67039
NCKAP1 NCK-associated protein 1 2.66327
USP6NL USP6 N-terminal like 2.65979
PLPP2 phospholipid phosphatase 2 2.65257
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 2.6505
SH3GLB1 SH3-domain GRB2-like endophilin B1 2.64047
NOTCH4 notch 4 2.63755
NT5E 5'-nucleotidase, ecto (CD73) 2.63158
PYGB phosphorylase, glycogen; brain 2.6306
EHD4 EH-domain containing 4 2.62726
DHRS7 dehydrogenase/reductase (SDR family) member 7 2.62467
HAX1 HCLS1 associated protein X-1 2.60695
ZEB2 zinc finger E-box binding homeobox 2 2.5936
LARP6 La ribonucleoprotein domain family, member 6 2.59174
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 2.59001
REM1 RAS (RAD and GEM)-like GTP-binding 1 2.58975
KYAT3 kynurenine aminotransferase 3 2.58969
PCDHGA5 protocadherin gamma subfamily A, 5 2.58547
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 2.58398
WSB2 WD repeat and SOCS box containing 2 2.57886
PLAUR plasminogen activator, urokinase receptor 2.57672
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 2.57609
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 2.57423
TRPV2 transient receptor potential cation channel, subfamily V, member 2 2.57113
RUFY1 RUN and FYVE domain containing 1 2.56776
LRRC8D leucine rich repeat containing 8 family, member D 2.56704
PRSS2 protease, serine, 2 (trypsin 2) 2.56283
WDR13 WD repeat domain 13 2.55784
TMEM53 transmembrane protein 53 2.55572
TMEM147 transmembrane protein 147 2.54572
FES FES proto-oncogene, tyrosine kinase 2.53684
KATNBL1 katanin p80 subunit B-like 1 2.53227
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2.52957
TSG101 tumor susceptibility 101 2.52462
PCDH17 protocadherin 17 2.52412
IPO13 importin 13 2.51743
PRSS3 protease, serine, 3 2.51566
KIF3C kinesin family member 3C 2.51218
RAB4B RAB4B, member RAS oncogene family 2.51087
PTPRE protein tyrosine phosphatase, receptor type, E 2.50842
RSU1 Ras suppressor protein 1 2.50547
NCLN nicalin 2.5053
TRIP4 thyroid hormone receptor interactor 4 2.50457
ARMCX1 armadillo repeat containing, X-linked 1 2.50399
XPOT exportin, tRNA 2.49996
GATA6 GATA binding protein 6 2.4914
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1 2.49103
MFSD6 major facilitator superfamily domain containing 6 2.48961
DUSP28 dual specificity phosphatase 28 2.48323
TUBB6 tubulin, beta 6 class V 2.48112
HLX H2.0-like homeobox 2.4782
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) 2.47708
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 2.4754
BSPRY B-box and SPRY domain containing 2.47422
GBE1 glucan (1,4-alpha-), branching enzyme 1 2.4706
PLAAT3 phospholipase A and acyltransferase 3 2.46945
VTCN1 V-set domain containing T cell activation inhibitor 1 2.46488
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 2.45773
STN1 STN1 subunit of CST complex 2.45045
FAM50A family with sequence similarity 50, member A 2.44669
RMC1 regulator of MON1-CCZ1 2.44371
GPKOW G patch domain and KOW motifs 2.44235
PTK6 protein tyrosine kinase 6 2.4401
S100A11 S100 calcium binding protein A11 2.43756
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 2.43487
UBE2L6 ubiquitin-conjugating enzyme E2L 6 2.43344
MST1R macrophage stimulating 1 receptor 2.42771
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) 2.42724
MT1M metallothionein 1M 2.426
AK5 adenylate kinase 5 2.42111
CLIP3 CAP-GLY domain containing linker protein 3 2.42068
ZPR1 ZPR1 zinc finger 2.41838
KLK5 kallikrein-related peptidase 5 2.41272
NGRN neugrin, neurite outgrowth associated 2.40945
TSPO translocator protein (18kDa) 2.40846
PFDN2 prefoldin subunit 2 2.40716
GFPT1 glutamine--fructose-6-phosphate transaminase 1 2.40514
SCGB2A2 secretoglobin, family 2A, member 2 2.40363
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 2.40295
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 2.40126
MAPK12 mitogen-activated protein kinase 12 2.40013
PRR13 proline rich 13 2.3923
OLAH oleoyl-ACP hydrolase 2.39146
CEP170 centrosomal protein 170kDa 2.39059
TERF2IP telomeric repeat binding factor 2, interacting protein 2.38994
SCAMP4 secretory carrier membrane protein 4 2.38129
NPTX2 neuronal pentraxin II 2.36928
ANGPTL4 angiopoietin-like 4 2.36773
TRIM13 tripartite motif containing 13 2.36451
RHOC ras homolog family member C 2.36013
CAMK1D calcium/calmodulin-dependent protein kinase ID 2.3577
KLK6 kallikrein-related peptidase 6 2.35017
GRAMD1C GRAM domain containing 1C 2.34702
KANK3 KN motif and ankyrin repeat domains 3 2.3469
KCNIP1 Kv channel interacting protein 1 2.33963
SCPEP1 serine carboxypeptidase 1 2.33631
WASHC5 WASH complex subunit 5 2.33516
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 2.33289
PRKCD protein kinase C, delta 2.3325
MRPS18A mitochondrial ribosomal protein S18A 2.33141
SNRNP27 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) 2.32302
SLC31A2 solute carrier family 31 (copper transporter), member 2 2.32113
PRR16 proline rich 16 2.31905
SCGB1D2 secretoglobin, family 1D, member 2 2.31789
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 2.31755
PRELID3B PRELI domain containing 3B 2.31752
TREX2 three prime repair exonuclease 2 2.31522
CDCP1 CUB domain containing protein 1 2.3151
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 2.31314
CYB5R1 cytochrome b5 reductase 1 2.3102
VASH1 vasohibin 1 2.30991
SYBU syntabulin (syntaxin-interacting) 2.30798
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 2.30764
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 2.30184
TPH1 tryptophan hydroxylase 1 2.30129
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 2.29536
PHF11 PHD finger protein 11 2.29513
TTC4 tetratricopeptide repeat domain 4 2.29511
ANKRD6 ankyrin repeat domain 6 2.29233
RCN1 reticulocalbin 1, EF-hand calcium binding domain 2.28638
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 2.28112
STEAP1B STEAP family member 1B 2.28056
ZNF250 zinc finger protein 250 2.27872
ARHGAP22 Rho GTPase activating protein 22 2.27787
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta 2.2757
ACTR10 actin-related protein 10 homolog (S. cerevisiae) 2.27471
ANO1 anoctamin 1, calcium activated chloride channel 2.27242
HTRA2 HtrA serine peptidase 2 2.27032
INHBE inhibin, beta E 2.26873
TIMP1 TIMP metallopeptidase inhibitor 1 2.26871
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13 2.26811
EDN3 endothelin 3 2.26782
KLF2 Kruppel-like factor 2 2.26666
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 2.2656
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein 2.265
RASL11B RAS-like, family 11, member B 2.26097
ATF4 activating transcription factor 4 2.26088
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2 2.25601
ZNF410 zinc finger protein 410 2.25542
E2F2 E2F transcription factor 2 2.24811
FLII flightless I homolog (Drosophila) 2.24556
ADAP1 ArfGAP with dual PH domains 1 2.24446
TAGLN3 transgelin 3 2.24432
RUSC2 RUN and SH3 domain containing 2 2.24369
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) 2.23983
PDE1A phosphodiesterase 1A, calmodulin-dependent 2.23649
FXYD5 FXYD domain containing ion transport regulator 5 2.23515
PSAT1 phosphoserine aminotransferase 1 2.23219
ADAM9 ADAM metallopeptidase domain 9 2.23039
BCAN brevican 2.2294
CIB1 calcium and integrin binding 1 (calmyrin) 2.22613
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 2.22231
TH tyrosine hydroxylase 2.22207
PCDHB11 protocadherin beta 11 2.21904
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) 2.2181
MSANTD3-TMEFF1 MSANTD3-TMEFF1 readthrough 2.21746
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 2.21739
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 2.21602
KLK8 kallikrein-related peptidase 8 2.21297
NSFL1C NSFL1 (p97) cofactor (p47) 2.21259
GADD45A growth arrest and DNA-damage-inducible, alpha 2.21242
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 2.21135
SEC23B Sec23 homolog B (S. cerevisiae) 2.20669
JCAD junctional cadherin 5 associated 2.20649
THBS3 thrombospondin 3 2.20285
TMPRSS3 transmembrane protease, serine 3 2.1991
PLD3 phospholipase D family, member 3 2.19801
LOC100652777 group 10 secretory phospholipase A2-like 2.19729
PIGK phosphatidylinositol glycan anchor biosynthesis, class K 2.19656
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 2.19448
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 2.19349
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 2.19323
CLIC5 chloride intracellular channel 5 2.18886
EMC7 ER membrane protein complex subunit 7 2.18881
RHBDF1 rhomboid 5 homolog 1 (Drosophila) 2.18365
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.18329
CEP15 centrosomal protein 15 2.18236
DUSP12 dual specificity phosphatase 12 2.17734
SOX4 SRY (sex determining region Y)-box 4 2.1695
TPPP3 tubulin polymerization-promoting protein family member 3 2.16898
BCL10 B-cell CLL/lymphoma 10 2.16711
BYSL bystin-like 2.1646
POLL polymerase (DNA directed), lambda 2.16426
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 2.16288
LTC4S leukotriene C4 synthase 2.16188
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 2.16177
TICAM1 toll-like receptor adaptor molecule 1 2.1609
DSE dermatan sulfate epimerase 2.15969
ASIC4 acid sensing (proton gated) ion channel family member 4 2.15712
HOMER3 homer scaffolding protein 3 2.15663
NDRG4 NDRG family member 4 2.15539
ATF3 activating transcription factor 3 2.15491
ICAM5 intercellular adhesion molecule 5, telencephalin 2.15441
SLC35G2 solute carrier family 35, member G2 2.15358
TMED5 transmembrane emp24 protein transport domain containing 5 2.15168
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa 2.15163
TGFB1I1 transforming growth factor beta 1 induced transcript 1 2.14933
THBD thrombomodulin 2.14897
CALHM2 calcium homeostasis modulator 2 2.14477
CYTH2 cytohesin 2 2.14472
PLAAT2 phospholipase A and acyltransferase 2 2.14262
LRRN2 leucine rich repeat neuronal 2 2.14122
ASL argininosuccinate lyase 2.14047
PDCD6IP programmed cell death 6 interacting protein 2.13759
DTD1 D-tyrosyl-tRNA deacylase 1 2.13534
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative) 2.13465
SYT17 synaptotagmin XVII 2.13414
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 2.13405
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 2.13322
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 2.13258
AUP1 ancient ubiquitous protein 1 2.1295
CALB2 calbindin 2 2.12701
PLAAT1 phospholipase A and acyltransferase 1 2.12596
CSN1S1 casein alpha s1 2.12387
RHOQ ras homolog family member Q 2.12311
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 2.12198
GLRX2 glutaredoxin 2 2.12198
VAMP5 vesicle-associated membrane protein 5 2.12059
ELF5 E74-like factor 5 (ets domain transcription factor) 2.11969
CCRL2 chemokine (C-C motif) receptor-like 2 2.11761
GPX4 glutathione peroxidase 4 2.1175
TMEM184B transmembrane protein 184B 2.11732
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 2.11154
GNG5 guanine nucleotide binding protein (G protein), gamma 5 2.11089
GPR137B G protein-coupled receptor 137B 2.1089
DCX doublecortin 2.10592
PANK2 pantothenate kinase 2 2.10494
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.10138
CLIP4 CAP-GLY domain containing linker protein family, member 4 2.09833
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 2.09578
SLC35F6 solute carrier family 35, member F6 2.09499
GJA4 gap junction protein, alpha 4, 37kDa 2.09247
TMEM204 transmembrane protein 204 2.08894
RAB11FIP5 RAB11 family interacting protein 5 (class I) 2.08415
RTN4 reticulon 4 2.08412
ATG7 autophagy related 7 2.08404
TCN2 transcobalamin II 2.08316
TMBIM1 transmembrane BAX inhibitor motif containing 1 2.08192
SV2A synaptic vesicle glycoprotein 2A 2.08192
SEPTIN5 septin 5 2.08053
SPINT1 serine peptidase inhibitor, Kunitz type 1 2.07843
TIMP2 TIMP metallopeptidase inhibitor 2 2.07741
MAN2B2 mannosidase, alpha, class 2B, member 2 2.07427
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 2.07044
TRAPPC11 trafficking protein particle complex 11 2.07042
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 2.07017
OR10H1 olfactory receptor, family 10, subfamily H, member 1 2.06636
MGLL monoglyceride lipase 2.06583
ELANE elastase, neutrophil expressed 2.06278
AHCYL1 adenosylhomocysteinase-like 1 2.06031
LRRC49 leucine rich repeat containing 49 2.06005
KLHL2 kelch-like family member 2 2.05601
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 2.05527
GSTT2B glutathione S-transferase theta 2B (gene/pseudogene) 2.05522
SH3YL1 SH3 and SYLF domain containing 1 2.05519
ADIRF adipogenesis regulatory factor 2.05388
YES1 YES proto-oncogene 1, Src family tyrosine kinase 2.05115
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 2.04985
HAPLN1 hyaluronan and proteoglycan link protein 1 2.04749
TREM1 triggering receptor expressed on myeloid cells 1 2.04734
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.04692
NPDC1 neural proliferation, differentiation and control, 1 2.04394
BIK BCL2-interacting killer (apoptosis-inducing) 2.04352
PTPRN protein tyrosine phosphatase, receptor type, N 2.04077
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 2.03982
MPDU1 mannose-P-dolichol utilization defect 1 2.03702
NAGLU N-acetylglucosaminidase, alpha 2.03698
SLC67A1 solute carrier family 67 member 1 2.03615
IARS1 isoleucyl-tRNA synthetase 1 2.0358
DDAH1 dimethylarginine dimethylaminohydrolase 1 2.03518
CD300C CD300c molecule 2.03361
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) 2.03297
GGT5 gamma-glutamyltransferase 5 2.03276
TRIM36 tripartite motif containing 36 2.03122
VRK2 vaccinia related kinase 2 2.02922
GRIA4 glutamate receptor, ionotropic, AMPA 4 2.02666
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 2.02612
RSBN1 round spermatid basic protein 1 2.02287
FOXI1 forkhead box I1 2.0217
SYNGR3 synaptogyrin 3 2.02143
CDC42SE1 CDC42 small effector 1 2.0205
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) 2.01905
PHLDA2 pleckstrin homology-like domain, family A, member 2 2.01812
RPF1 ribosome production factor 1 homolog (S. cerevisiae) 2.01643
QTMAN queuosine-tRNA mannosyltransferase 2.01582
FOXD1 forkhead box D1 2.01485
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 2.01439
NCF2 neutrophil cytosolic factor 2 2.00887
WARS1 tryptophanyl-tRNA synthetase 1 2.00825
LIF leukemia inhibitory factor 2.00683
TALDO1 transaldolase 1 2.00411
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 2.00343
KCTD14 potassium channel tetramerization domain containing 14 2.00302
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 2.00007

decreased expression

Symbol Name Standardized Value
RPS4Y1 ribosomal protein S4, Y-linked 1 -7.21207
CENPE centromere protein E, 312kDa -6.73408
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -6.72412
MCM3 minichromosome maintenance complex component 3 -5.50137
C2CD5 C2 calcium-dependent domain containing 5 -5.49238
KIF20A kinesin family member 20A -5.20681
PECR peroxisomal trans-2-enoyl-CoA reductase -5.1488
APOA2 apolipoprotein A-II -5.10556
TOP2A topoisomerase (DNA) II alpha 170kDa -5.05525
BIRC5 baculoviral IAP repeat containing 5 -4.97534
CCNB2 cyclin B2 -4.8808
STMN1 stathmin 1 -4.85222
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -4.79126
CCNA2 cyclin A2 -4.69988
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -4.51734
LBR lamin B receptor -4.50536
MYCBP MYC binding protein -4.45481
NUSAP1 nucleolar and spindle associated protein 1 -4.44005
KIF4A kinesin family member 4A -4.41227
CDC20 cell division cycle 20 -4.29088
PYGL phosphorylase, glycogen, liver -4.26273
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -4.22386
PDLIM1 PDZ and LIM domain 1 -4.19901
CCNB1 cyclin B1 -4.17047
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -4.15204
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -4.06336
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -4.05351
ASF1B anti-silencing function 1B histone chaperone -4.00067
B4GAT1 beta-1,4-glucuronyltransferase 1 -3.98818
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -3.97428
CDK1 cyclin-dependent kinase 1 -3.88195
TTK TTK protein kinase -3.85811
FEN1 flap structure-specific endonuclease 1 -3.84289
KIF11 kinesin family member 11 -3.76931
APOH apolipoprotein H (beta-2-glycoprotein I) -3.75438
C5 complement component 5 -3.7538
NCAPH non-SMC condensin I complex, subunit H -3.73888
HMMR hyaluronan-mediated motility receptor (RHAMM) -3.7223
ZBTB35 zinc finger and BTB domain containing 35 -3.68742
SPAG5 sperm associated antigen 5 -3.68534
MCM5 minichromosome maintenance complex component 5 -3.65922
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -3.62706
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.61707
TPX2 TPX2, microtubule-associated -3.60267
POLR1A polymerase (RNA) I polypeptide A, 194kDa -3.59083
OIP5 Opa interacting protein 5 -3.58662
RHOB ras homolog family member B -3.58314
DHFR dihydrofolate reductase -3.5614
SESN1 sestrin 1 -3.55299
HELZ helicase with zinc finger -3.53912
GINS2 GINS complex subunit 2 (Psf2 homolog) -3.51704
KIF15 kinesin family member 15 -3.5105
PTTG1 pituitary tumor-transforming 1 -3.50947
MCM10 minichromosome maintenance complex component 10 -3.46286
TRMT5 tRNA methyltransferase 5 -3.45622
HJURP Holliday junction recognition protein -3.41793
MKI67 marker of proliferation Ki-67 -3.35195
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.35115
HMGB2 high mobility group box 2 -3.32339
TMEM97 transmembrane protein 97 -3.30694
ATP5MF ATP synthase membrane subunit f -3.29689
SPDL1 spindle apparatus coiled-coil protein 1 -3.27019
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -3.26625
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 -3.26158
ZWILCH zwilch kinetochore protein -3.24436
KIF23 kinesin family member 23 -3.22652
ERCC6L excision repair cross-complementation group 6-like -3.22034
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -3.20489
CTSC cathepsin C -3.20447
NCAPD2 non-SMC condensin I complex, subunit D2 -3.18537
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa -3.17536
SPC25 SPC25, NDC80 kinetochore complex component -3.15257
YTHDC1 YTH domain containing 1 -3.14833
HMGN2 high mobility group nucleosomal binding domain 2 -3.14719
CDC25C cell division cycle 25C -3.1035
CDCA3 cell division cycle associated 3 -3.08537
CENPA centromere protein A -3.08526
BRCA1 breast cancer 1, early onset -3.07466
TROAP trophinin associated protein -3.07035
PLK1 polo-like kinase 1 -3.06991
CCL16 chemokine (C-C motif) ligand 16 -3.06358
ZNF10 zinc finger protein 10 -3.04715
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 -3.01439
PBK PDZ binding kinase -3.008
SOAT2 sterol O-acyltransferase 2 -3.00766
CDK6 cyclin-dependent kinase 6 -3.00738
PRC1 protein regulator of cytokinesis 1 -3.00623
PM20D1 peptidase M20 domain containing 1 -3.00257
CDKN3 cyclin-dependent kinase inhibitor 3 -2.98939
XPO7 exportin 7 -2.98662
UXT ubiquitously-expressed, prefoldin-like chaperone -2.98535
NASP nuclear autoantigenic sperm protein (histone-binding) -2.98258
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -2.96561
LMNB1 lamin B1 -2.95911
BANF1 barrier to autointegration factor 1 -2.94972
CDCA8 cell division cycle associated 8 -2.94882
ANKRD49 ankyrin repeat domain 49 -2.94394
ZNF266 zinc finger protein 266 -2.93614
MBNL3 muscleblind-like splicing regulator 3 -2.92511
SCARA3 scavenger receptor class A, member 3 -2.91756
AURKA aurora kinase A -2.90959
POU2F1 POU class 2 homeobox 1 -2.90091
ZMYM1 zinc finger, MYM-type 1 -2.85276
PPT2 palmitoyl-protein thioesterase 2 -2.85151
ERC1 ELKS/RAB6-interacting/CAST family member 1 -2.84709
CKAP2 cytoskeleton associated protein 2 -2.84437
CDCA4 cell division cycle associated 4 -2.84409
CENPN centromere protein N -2.82977
PCLAF PCNA clamp associated factor -2.82735
MREG melanoregulin -2.82572
HIRIP3 HIRA interacting protein 3 -2.81887
LAMC1 laminin, gamma 1 (formerly LAMB2) -2.81304
MCM6 minichromosome maintenance complex component 6 -2.80408
HELLS helicase, lymphoid-specific -2.79434
TF transferrin -2.78746
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 -2.783
ALG8 ALG8, alpha-1,3-glucosyltransferase -2.78094
MIS18A MIS18 kinetochore protein A -2.77906
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -2.77824
WDR82 WD repeat domain 82 -2.77709
HTD2 hydroxyacyl-thioester dehydratase type 2 -2.77348
ANAPC2 anaphase promoting complex subunit 2 -2.76712
RFC3 replication factor C (activator 1) 3, 38kDa -2.76442
ADH6 alcohol dehydrogenase 6 (class V) -2.76244
PLK4 polo-like kinase 4 -2.75176
RRM2 ribonucleotide reductase M2 -2.73209
ADRB2 adrenoceptor beta 2, surface -2.72958
MTTP microsomal triglyceride transfer protein -2.72951
TK1 thymidine kinase 1, soluble -2.71567
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -2.71305
LIPC lipase, hepatic -2.70604
CA5A carbonic anhydrase VA, mitochondrial -2.70325
MCM7 minichromosome maintenance complex component 7 -2.69874
ZNF384 zinc finger protein 384 -2.69638
NEK2 NIMA-related kinase 2 -2.69296
RESF1 retroelement silencing factor 1 -2.67951
UBE2C ubiquitin-conjugating enzyme E2C -2.67123
CDC6 cell division cycle 6 -2.6609
PURA purine-rich element binding protein A -2.6578
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -2.65441
TUBGCP5 tubulin, gamma complex associated protein 5 -2.64621
CXADR coxsackie virus and adenovirus receptor -2.64519
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.64278
PDIA4 protein disulfide isomerase family A, member 4 -2.6379
CFI complement factor I -2.63318
GTSE1 G-2 and S-phase expressed 1 -2.62606
PROS1 protein S (alpha) -2.6239
NUP85 nucleoporin 85kDa -2.62263
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -2.61985
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1 -2.61713
CNOT1 CCR4-NOT transcription complex, subunit 1 -2.61219
WBP11 WW domain binding protein 11 -2.61054
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -2.60944
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) -2.59646
TSPAN6 tetraspanin 6 -2.59553
VRK1 vaccinia related kinase 1 -2.5937
MLEC malectin -2.59119
GTF2I general transcription factor IIi -2.59078
DCAF6 DDB1 and CUL4 associated factor 6 -2.5836
RFC2 replication factor C (activator 1) 2, 40kDa -2.5813
RACGAP1 Rac GTPase activating protein 1 -2.5784
PLEKHA5 pleckstrin homology domain containing, family A member 5 -2.57656
MVD mevalonate (diphospho) decarboxylase -2.57647
SH3D19 SH3 domain containing 19 -2.56733
KLF13 Kruppel-like factor 13 -2.56565
TUBD1 tubulin, delta 1 -2.56324
HPR haptoglobin-related protein -2.56079
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 -2.5602
HADH hydroxyacyl-CoA dehydrogenase -2.5589
PAGR1 PAXIP1 associated glutamate-rich protein 1 -2.55547
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit -2.55189
IL17RB interleukin 17 receptor B -2.54409
KIFC1 kinesin family member C1 -2.53139
MPC2 mitochondrial pyruvate carrier 2 -2.53027
BCAS3 breast carcinoma amplified sequence 3 -2.51977
VAV3 vav 3 guanine nucleotide exchange factor -2.51712
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D -2.51641
SASH3 SAM and SH3 domain containing 3 -2.51156
NUCB1 nucleobindin 1 -2.5075
NUP160 nucleoporin 160kDa -2.49756
CETN2 centrin, EF-hand protein, 2 -2.49641
A1CF APOBEC1 complementation factor -2.49238
BARD1 BRCA1 associated RING domain 1 -2.48813
PRCP prolylcarboxypeptidase (angiotensinase C) -2.48067
C1S complement component 1, s subcomponent -2.47956
NPR2 natriuretic peptide receptor 2 -2.47585
IFNA13 interferon, alpha 13 -2.47437
IDI1 isopentenyl-diphosphate delta isomerase 1 -2.47315
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae) -2.46792
KIF18A kinesin family member 18A -2.46622
FANCC Fanconi anemia, complementation group C -2.46503
LRP5 low density lipoprotein receptor-related protein 5 -2.46454
NCAPG2 non-SMC condensin II complex, subunit G2 -2.45764
CD99 CD99 molecule -2.45663
AMACR alpha-methylacyl-CoA racemase -2.45586
DUT deoxyuridine triphosphatase -2.45559
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 -2.45334
PDE3B phosphodiesterase 3B, cGMP-inhibited -2.45062
KIF18B kinesin family member 18B -2.44728
FRS2 fibroblast growth factor receptor substrate 2 -2.44567
MUC5B mucin 5B, oligomeric mucus/gel-forming -2.44422
SHMT1 serine hydroxymethyltransferase 1 (soluble) -2.4347
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -2.43152
SHCBP1 SHC SH2-domain binding protein 1 -2.43145
ODAM odontogenic, ameloblast asssociated -2.42889
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -2.42574
RFX7 regulatory factor X, 7 -2.42544
ZXDC ZXD family zinc finger C -2.42298
CNTLN centlein, centrosomal protein -2.42185
MNS1 meiosis-specific nuclear structural 1 -2.42138
CDK19 cyclin-dependent kinase 19 -2.41833
CDC45 cell division cycle 45 -2.4166
S100B S100 calcium binding protein B -2.41056
GOLIM4 golgi integral membrane protein 4 -2.40878
PDIA3 protein disulfide isomerase family A, member 3 -2.40763
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 -2.40751
BMP4 bone morphogenetic protein 4 -2.40712
CHPF chondroitin polymerizing factor -2.40615
DCAF16 DDB1 and CUL4 associated factor 16 -2.40554
COPB2 coatomer protein complex, subunit beta 2 (beta prime) -2.40337
DONSON downstream neighbor of SON -2.4023
HMGB1 high mobility group box 1 -2.40195
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -2.4012
FBXO5 F-box protein 5 -2.40073
NXT2 nuclear transport factor 2-like export factor 2 -2.40018
ZBTB44 zinc finger and BTB domain containing 44 -2.39283
SLC30A10 solute carrier family 30, member 10 -2.39021
RNASE7 ribonuclease, RNase A family, 7 -2.38894
ORC6 origin recognition complex, subunit 6 -2.38753
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -2.38624
LOC112694756 uncharaterized LOC112694756 -2.38384
RBM4 RNA binding motif protein 4 -2.38119
LUC7L3 LUC7-like 3 (S. cerevisiae) -2.37424
RBBP6 retinoblastoma binding protein 6 -2.37253
DENND1C DENN/MADD domain containing 1C -2.37217
CD96 CD96 molecule -2.3715
ANAPC15 anaphase promoting complex subunit 15 -2.37109
TTC38 tetratricopeptide repeat domain 38 -2.37051
ASB9 ankyrin repeat and SOCS box containing 9 -2.37029
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -2.36941
NDC80 NDC80 kinetochore complex component -2.36677
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 -2.36481
CCDC15 coiled-coil domain containing 15 -2.36401
PDK2 pyruvate dehydrogenase kinase, isozyme 2 -2.361
CKS2 CDC28 protein kinase regulatory subunit 2 -2.35808
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 -2.35393
ISOC2 isochorismatase domain containing 2 -2.34965
DBF4 DBF4 zinc finger -2.34936
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 -2.34806
ATP5PF ATP synthase peripheral stalk subunit F6 -2.34788
FOXM1 forkhead box M1 -2.34553
CENPI centromere protein I -2.34412
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7 -2.34295
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa -2.34137
MAGT1 magnesium transporter 1 -2.3396
APOM apolipoprotein M -2.33518
RCOR3 REST corepressor 3 -2.33156
ALAD aminolevulinate dehydratase -2.32996
CENPS-CORT CENPS-CORT readthrough -2.32899
MOCS2 molybdenum cofactor synthesis 2 -2.32511
PNPLA3 patatin-like phospholipase domain containing 3 -2.32495
AP2M1 adaptor-related protein complex 2, mu 1 subunit -2.32204
PPIH peptidylprolyl isomerase H (cyclophilin H) -2.3202
NOL11 nucleolar protein 11 -2.31927
NUP93 nucleoporin 93kDa -2.31846
PCF11 PCF11 cleavage and polyadenylation factor subunit -2.31706
PRB4 proline-rich protein BstNI subfamily 4 -2.31246
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -2.31199
STX17 syntaxin 17 -2.31101
BRIX1 BRX1, biogenesis of ribosomes -2.31035
CHURC1-FNTB CHURC1-FNTB readthrough -2.31
DDB1 damage-specific DNA binding protein 1, 127kDa -2.30898
MORF4L2 mortality factor 4 like 2 -2.30093
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.29947
ZNF443 zinc finger protein 443 -2.2964
TFAM transcription factor A, mitochondrial -2.29397
PCYOX1 prenylcysteine oxidase 1 -2.2927
MSH2 mutS homolog 2 -2.28632
C4BPB complement component 4 binding protein, beta -2.28238
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 -2.2793
HOXA7 homeobox A7 -2.2782
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 -2.27788
SERINC5 serine incorporator 5 -2.27613
EXO1 exonuclease 1 -2.27289
KDM1A lysine (K)-specific demethylase 1A -2.27254
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) -2.27205
POLK polymerase (DNA directed) kappa -2.27155
THOC2 THO complex 2 -2.26791
BBS4 Bardet-Biedl syndrome 4 -2.26121
BORA bora, aurora kinase A activator -2.2586
PRR5 proline rich 5 (renal) -2.2584
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 -2.25546
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -2.25435
MDN1 MDN1, midasin homolog (yeast) -2.25365
ZNF813 zinc finger protein 813 -2.25284
ZWINT ZW10 interacting kinetochore protein -2.25199
TPR translocated promoter region, nuclear basket protein -2.24783
PIPOX pipecolic acid oxidase -2.24697
ZNF428 zinc finger protein 428 -2.24647
POM121C POM121 transmembrane nucleoporin C -2.24579
BCLAF1 BCL2-associated transcription factor 1 -2.24348
GINS3 GINS complex subunit 3 (Psf3 homolog) -2.24241
SLC67A2 solute carrier family 67 member 2 -2.24183
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.24064
PNISR PNN-interacting serine/arginine-rich protein -2.23716
OTC ornithine carbamoyltransferase -2.23583
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 -2.2347
MAPK9 mitogen-activated protein kinase 9 -2.2342
ANG angiogenin, ribonuclease, RNase A family, 5 -2.23264
EML4 echinoderm microtubule associated protein like 4 -2.23196
SLC2A4RG SLC2A4 regulator -2.23174
SRP9 signal recognition particle 9kDa -2.23165
ATF7IP2 activating transcription factor 7 interacting protein 2 -2.22927
RNASE4 ribonuclease, RNase A family, 4 -2.22866
HMGN1 high mobility group nucleosome binding domain 1 -2.22789
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa -2.22383
LIME1 Lck interacting transmembrane adaptor 1 -2.22253
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) -2.22235
ZKSCAN8 zinc finger with KRAB and SCAN domains 8 -2.22129
SLC39A7 solute carrier family 39 (zinc transporter), member 7 -2.21746
SIRPG signal-regulatory protein gamma -2.21614
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -2.21474
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.2132
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 -2.21082
ZMYM3 zinc finger, MYM-type 3 -2.20872
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -2.20829
MTUS1 microtubule associated tumor suppressor 1 -2.20802
AHCTF1 AT hook containing transcription factor 1 -2.20696
ZNF551 zinc finger protein 551 -2.2055
ASGR1 asialoglycoprotein receptor 1 -2.20432
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) -2.20392
MFAP4 microfibrillar-associated protein 4 -2.20136
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -2.20064
AURKB aurora kinase B -2.20056
MIS12 MIS12 kinetochore complex component -2.19916
ZNF587B zinc finger protein 587B -2.19848
PRUNE1 prune exopolyphosphatase 1 -2.19473
ZNF134 zinc finger protein 134 -2.19456
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae) -2.19153
UTRN utrophin -2.18686
UFM1 ubiquitin-fold modifier 1 -2.18631
ATAD5 ATPase family, AAA domain containing 5 -2.18589
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 -2.1839
SMN2 survival of motor neuron 2, centromeric -2.18286
FUS FUS RNA binding protein -2.18259
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -2.18215
ATAD2 ATPase family, AAA domain containing 2 -2.18055
L1TD1 LINE-1 type transposase domain containing 1 -2.17825
BPTF bromodomain PHD finger transcription factor -2.17728
SRSF1 serine/arginine-rich splicing factor 1 -2.17409
PPIG peptidylprolyl isomerase G (cyclophilin G) -2.17334
GLUL glutamate-ammonia ligase -2.16774
CD19 CD19 molecule -2.16335
LPAR6 lysophosphatidic acid receptor 6 -2.1576
PRMT7 protein arginine methyltransferase 7 -2.15729
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -2.15612
ITM2C integral membrane protein 2C -2.15543
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 -2.15259
POMK protein-O-mannose kinase -2.151
CA14 carbonic anhydrase XIV -2.14948
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -2.14936
MSH3 mutS homolog 3 -2.1481
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.14234
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 -2.13979
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -2.13877
ATRX alpha thalassemia/mental retardation syndrome X-linked -2.13877
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -2.13291
MSMO1 methylsterol monooxygenase 1 -2.13228
BPHL biphenyl hydrolase-like (serine hydrolase) -2.13205
COX7B cytochrome c oxidase subunit VIIb -2.13111
F7 coagulation factor VII (serum prothrombin conversion accelerator) -2.1305
SCAF11 SR-related CTD-associated factor 11 -2.12546
PARPBP PARP1 binding protein -2.12278
CERT1 ceramide transporter 1 -2.12235
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) -2.12228
SELENBP1 selenium binding protein 1 -2.11944
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.11714
AHSG alpha-2-HS-glycoprotein -2.11646
PCNT pericentrin -2.11487
ZNF200 zinc finger protein 200 -2.11286
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -2.11154
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 -2.11079
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -2.10916
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 -2.10888
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) -2.1074
CDK2 cyclin-dependent kinase 2 -2.10224
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 -2.10191
TRAT1 T cell receptor associated transmembrane adaptor 1 -2.10173
CHL1 cell adhesion molecule L1-like -2.10132
IFITM1 interferon induced transmembrane protein 1 -2.10116
TRH thyrotropin-releasing hormone -2.09903
PISD phosphatidylserine decarboxylase -2.09807
DSN1 DSN1, MIS12 kinetochore complex component -2.09718
ZNF12 zinc finger protein 12 -2.09181
KLHDC2 kelch domain containing 2 -2.09142
AUNIP aurora kinase A and ninein interacting protein -2.09058
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) -2.08942
TECR trans-2,3-enoyl-CoA reductase -2.08872
GYG2 glycogenin 2 -2.08738
NUP54 nucleoporin 54kDa -2.0861
LMAN2L lectin, mannose-binding 2-like -2.08558
TRIP13 thyroid hormone receptor interactor 13 -2.0854
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -2.07573
ASTE1 asteroid homolog 1 (Drosophila) -2.07132
MRFAP1L1 Morf4 family associated protein 1-like 1 -2.06687
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme -2.06498
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 -2.06444
CENPU centromere protein U -2.06174
CCS copper chaperone for superoxide dismutase -2.06154
SEC13 SEC13 homolog (S. cerevisiae) -2.06143
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) -2.05814
NONO non-POU domain containing, octamer-binding -2.05736
MTPAP mitochondrial poly(A) polymerase -2.05446
RAB1B RAB1B, member RAS oncogene family -2.05418
GALK1 galactokinase 1 -2.05241
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 -2.04933
COQ3 coenzyme Q3 methyltransferase -2.0483
FKTN fukutin -2.04674
EWSR1 EWS RNA-binding protein 1 -2.04513
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6 -2.04508
ADI1 acireductone dioxygenase 1 -2.04472
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -2.04326
CLCA1 chloride channel accessory 1 -2.04297
FAM8A1 family with sequence similarity 8, member A1 -2.0404
AAAS achalasia, adrenocortical insufficiency, alacrimia -2.03965
MGST2 microsomal glutathione S-transferase 2 -2.03916
GLRX5 glutaredoxin 5 -2.03624
DEPDC1 DEP domain containing 1 -2.036
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 -2.03313
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase -2.03254
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -2.03252
PSRC1 proline/serine-rich coiled-coil 1 -2.03169
METTL16 methyltransferase like 16 -2.0307
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) -2.02983
TARDBP TAR DNA binding protein -2.02885
FAM13B family with sequence similarity 13, member B -2.0268
LAS1L LAS1-like (S. cerevisiae) -2.02511
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -2.02059
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -2.01996
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 -2.01977
SETD2 SET domain containing 2 -2.01961
XPO1 exportin 1 -2.01873
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.01649
PRPF4B pre-mRNA processing factor 4B -2.01554
UBP1 upstream binding protein 1 (LBP-1a) -2.01517
POGLUT2 protein O-glucosyltransferase 2 -2.01338
PDK3 pyruvate dehydrogenase kinase, isozyme 3 -2.01308
JPT2 Jupiter microtubule associated homolog 2 -2.00963
RFXAP regulatory factor X-associated protein -2.00898
KIF22 kinesin family member 22 -2.00847
TACC3 transforming, acidic coiled-coil containing protein 3 -2.00836
URM1 ubiquitin related modifier 1 -2.00769
KRT33A keratin 33A, type I -2.00729
FNBP4 formin binding protein 4 -2.00662
FCGBP Fc fragment of IgG binding protein -2.0063
ZBTB24 zinc finger and BTB domain containing 24 -2.00613
H2AJ H2A.J histone -2.00591
LAMA5 laminin, alpha 5 -2.00297
RAD51AP1 RAD51 associated protein 1 -2.00091
RNF167 ring finger protein 167 -2.00035