CRCGN015_HEPG2_48H:A17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description shahrm perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

37 genes differentially expressed following the CRCGN015_HEPG2_48H:A17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PRKCQ protein kinase C, theta 2.79182
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 2.65699
USP6NL USP6 N-terminal like 2.59287
PMM2 phosphomannomutase 2 2.55479
PWP2 PWP2 periodic tryptophan protein homolog (yeast) 2.48569
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 2.43847
PFKL phosphofructokinase, liver 2.37798
NIT1 nitrilase 1 2.23666
FGB fibrinogen beta chain 2.22977
MTG1 mitochondrial ribosome-associated GTPase 1 2.2095
IL4R interleukin 4 receptor 2.16095
RPL39L ribosomal protein L39-like 2.1023
GDF10 growth differentiation factor 10 2.08946
MSL1 male-specific lethal 1 homolog (Drosophila) 2.08838
TEDC2 tubulin epsilon and delta complex 2 2.06832
VGLL4 vestigial-like family member 4 2.0589
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) 2.04382
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 2.02469
IRF2BP1 interferon regulatory factor 2 binding protein 1 2.0125
ZNF219 zinc finger protein 219 2.00059

decreased expression

Symbol Name Standardized Value
STAT1 signal transducer and activator of transcription 1, 91kDa -3.82397
RNF167 ring finger protein 167 -3.57187
DERA deoxyribose-phosphate aldolase (putative) -3.43696
PRPF4 pre-mRNA processing factor 4 -3.40649
ERCC5 excision repair cross-complementation group 5 -2.58861
PECR peroxisomal trans-2-enoyl-CoA reductase -2.52209
CHMP1B charged multivesicular body protein 1B -2.33655
COTL1 coactosin-like F-actin binding protein 1 -2.21189
BIRC2 baculoviral IAP repeat containing 2 -2.19428
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 -2.18885
SCYL2 SCY1-like 2 (S. cerevisiae) -2.13074
PALLD palladin, cytoskeletal associated protein -2.09619
SNX19 sorting nexin 19 -2.08979
BCL10 B-cell CLL/lymphoma 10 -2.07227
PDLIM1 PDZ and LIM domain 1 -2.04093
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -2.00599
CALU calumenin -2.00149