CRCGN015_HEPG2_48H:A18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description shahrm perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

19 genes differentially expressed following the CRCGN015_HEPG2_48H:A18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GSTM2 glutathione S-transferase mu 2 (muscle) 2.63136
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.51862
SCRN1 secernin 1 2.47361
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 2.34365
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 2.32343
TBPL1 TBP-like 1 2.24935

decreased expression

Symbol Name Standardized Value
DHRS7 dehydrogenase/reductase (SDR family) member 7 -4.27543
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -3.92589
JPT1 Jupiter microtubule associated homolog 1 -2.96079
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.86652
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -2.3714
RPS4Y1 ribosomal protein S4, Y-linked 1 -2.25343
MRPL58 mitochondrial ribosomal protein L58 -2.23936
ACOX1 acyl-CoA oxidase 1, palmitoyl -2.15542
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 -2.15009
MRPS7 mitochondrial ribosomal protein S7 -2.14606
NUP85 nucleoporin 85kDa -2.13603
MT1X metallothionein 1X -2.0867
LLGL2 lethal giant larvae homolog 2 (Drosophila) -2.03642