CRCGN015_HEPG2_48H:A20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-[4-(5-nitro-2-furyl)-2-thiazo?lyl]formamide 32.78 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

20 genes differentially expressed following the CRCGN015_HEPG2_48H:A20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
FPGS folylpolyglutamate synthase 3.33892
BAD BCL2-associated agonist of cell death 2.68487
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) 2.52069
ADRB2 adrenoceptor beta 2, surface 2.44816
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.23878
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.22002
PLSCR3 phospholipid scramblase 3 2.15914
CPOX coproporphyrinogen oxidase 2.10449
HYOU1 hypoxia up-regulated 1 2.06791

decreased expression

Symbol Name Standardized Value
TM9SF3 transmembrane 9 superfamily member 3 -4.50312
COG7 component of oligomeric golgi complex 7 -3.85762
S100P S100 calcium binding protein P -3.04966
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.67867
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae) -2.17481
CXADR coxsackie virus and adenovirus receptor -2.13888
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) -2.07722
NBR1 neighbor of BRCA1 gene 1 -2.02118
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -2.01526
CD2AP CD2-associated protein -2.00665
ANKZF1 ankyrin repeat and zinc finger domain containing 1 -2.00296