CRCGN015_HEPG2_48H:A23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description (4-chloro-2-methylphenoxy)acetic acid 35.53 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

15 genes differentially expressed following the CRCGN015_HEPG2_48H:A23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PLSCR3 phospholipid scramblase 3 3.1871
HOXA10-HOXA9 HOXA10-HOXA9 readthrough 2.60666
HOXA10 homeobox A10 2.52465
RAB31 RAB31, member RAS oncogene family 2.3121
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.17922
METRN meteorin, glial cell differentiation regulator 2.08422
PMM2 phosphomannomutase 2 2.05614

decreased expression

Symbol Name Standardized Value
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -3.64536
TM9SF3 transmembrane 9 superfamily member 3 -2.60316
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -2.41626
MT1X metallothionein 1X -2.32845
RNMT RNA (guanine-7-) methyltransferase -2.25475
CD2AP CD2-associated protein -2.20598
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 -2.0744
MACF1 microtubule-actin crosslinking factor 1 -2.02489