CRCGN015_HEPG2_48H:B03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

33 genes differentially expressed following the CRCGN015_HEPG2_48H:B03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CHN1 chimerin 1 4.39258
METRN meteorin, glial cell differentiation regulator 3.59303
ATP11B ATPase, class VI, type 11B 3.31179
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.23284
FPGS folylpolyglutamate synthase 3.14197
EPN2 epsin 2 2.9496
SCRN1 secernin 1 2.87007
ABHD6 abhydrolase domain containing 6 2.7232
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 2.62577
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.56965
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.56476
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 2.48859
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 2.4406
RNPS1 RNA binding protein S1, serine-rich domain 2.22795
MELK maternal embryonic leucine zipper kinase 2.18383
SUSD5 sushi domain containing 5 2.13115
FSD1 fibronectin type III and SPRY domain containing 1 2.10011

decreased expression

Symbol Name Standardized Value
TM9SF3 transmembrane 9 superfamily member 3 -3.97868
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -3.80864
PRPF4 pre-mRNA processing factor 4 -3.50802
HSPA8 heat shock 70kDa protein 8 -3.44889
LYPLA1 lysophospholipase I -3.27592
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -2.72241
EPCAM epithelial cell adhesion molecule -2.65506
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.43705
JMJD6 jumonji domain containing 6 -2.36848
TEX10 testis expressed 10 -2.29568
NCALD neurocalcin delta -2.20544
PROM1 prominin 1 -2.19152
EIF3L eukaryotic translation initiation factor 3, subunit L -2.08569
PRH1 proline-rich protein HaeIII subfamily 1 -2.07344
TBC1D31 TBC1 domain family, member 31 -2.02326
ATG4A autophagy related 4A, cysteine peptidase -2.00845