CRCGN015_HEPG2_48H:B04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

35 genes differentially expressed following the CRCGN015_HEPG2_48H:B04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SPAG4 sperm associated antigen 4 4.81184
LAGE3 L antigen family, member 3 4.63993
MAP7 microtubule-associated protein 7 3.83757
ANO10 anoctamin 10 3.39814
SNAP25 synaptosomal-associated protein, 25kDa 2.44822
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 2.02988
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 2.02327

decreased expression

Symbol Name Standardized Value
S100P S100 calcium binding protein P -5.75752
NCK1 NCK adaptor protein 1 -4.29796
PCNA proliferating cell nuclear antigen -4.04136
LYPLA1 lysophospholipase I -4.00861
HEATR1 HEAT repeat containing 1 -3.64892
VAT1 vesicle amine transport 1 -2.96647
LYPLA1-TCEA1 LYPLA1-TCEA1 readthrough -2.93139
CORO2A coronin, actin binding protein, 2A -2.92463
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -2.76897
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -2.72698
TM9SF3 transmembrane 9 superfamily member 3 -2.61877
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 -2.52228
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -2.43482
TRIM13 tripartite motif containing 13 -2.41953
RHEB Ras homolog enriched in brain -2.34916
PLAAT4 phospholipase A and acyltransferase 4 -2.31407
TF transferrin -2.31139
TMEM230 transmembrane protein 230 -2.19664
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H -2.18376
LPAR6 lysophosphatidic acid receptor 6 -2.13144
IL17RB interleukin 17 receptor B -2.10241
SNX5 sorting nexin 5 -2.08642
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 -2.06848
ACP5 acid phosphatase 5, tartrate resistant -2.068
ZNF304 zinc finger protein 304 -2.06068
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -2.05496
INPP1 inositol polyphosphate-1-phosphatase -2.04938
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 -2.04447