CRCGN015_HEPG2_48H:B05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

13 genes differentially expressed following the CRCGN015_HEPG2_48H:B05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
KDM5A lysine (K)-specific demethylase 5A 3.54059
TBPL1 TBP-like 1 2.43571
RAD51AP1 RAD51 associated protein 1 2.32638
VEGFD vascular endothelial growth factor D 2.21591
ORC3 origin recognition complex, subunit 3 2.19213
SF3A3 splicing factor 3a, subunit 3, 60kDa 2.18844
FBXO11 F-box protein 11 2.10453
LYRM1 LYR motif containing 1 2.03272

decreased expression

Symbol Name Standardized Value
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -4.4512
RPS4Y1 ribosomal protein S4, Y-linked 1 -3.79868
PCCB propionyl CoA carboxylase, beta polypeptide -2.63086
HPRT1 hypoxanthine phosphoribosyltransferase 1 -2.2149
MAP6D1 MAP6 domain containing 1 -2.01481