CRCGN015_HEPG2_48H:B06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

18 genes differentially expressed following the CRCGN015_HEPG2_48H:B06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
STAP2 signal transducing adaptor family member 2 3.25021
PNKP polynucleotide kinase 3'-phosphatase 2.84713
SSBP2 single-stranded DNA binding protein 2 2.68169
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.37317
ZNF274 zinc finger protein 274 2.27925
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 2.23078
EPHB2 EPH receptor B2 2.07698
SQOR sulfide quinone oxidoreductase 2.06393

decreased expression

Symbol Name Standardized Value
CRK v-crk avian sarcoma virus CT10 oncogene homolog -3.2364
S100P S100 calcium binding protein P -2.94167
DIPK1A divergent protein kinase domain 1A -2.56285
RHOB ras homolog family member B -2.46041
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -2.40684
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.38241
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -2.37105
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 -2.2781
CXADR coxsackie virus and adenovirus receptor -2.22842
PSD3 pleckstrin and Sec7 domain containing 3 -2.20726