CRCGN015_HEPG2_48H:B12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description sulfuric acid compound with 2-methyl-1,4-benzenediamine (1:1) 11.15 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

489 genes differentially expressed following the CRCGN015_HEPG2_48H:B12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
VAT1 vesicle amine transport 1 5.63486
FHL2 four and a half LIM domains 2 5.58989
TRIB3 tribbles pseudokinase 3 5.54104
INPP1 inositol polyphosphate-1-phosphatase 4.44464
SQOR sulfide quinone oxidoreductase 4.4274
TXNRD1 thioredoxin reductase 1 4.37726
CTSL cathepsin L 4.28571
NANOS3 nanos homolog 3 (Drosophila) 4.21788
SQSTM1 sequestosome 1 4.13619
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 4.08504
TRIB1 tribbles pseudokinase 1 3.99639
GARS1 glycyl-tRNA synthetase 1 3.88217
PPARG peroxisome proliferator-activated receptor gamma 3.79216
CEMIP2 cell migration inducing hyaluronidase 2 3.77179
FOSL1 FOS-like antigen 1 3.74313
ZFP36 ZFP36 ring finger protein 3.71385
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 3.65142
CDPF1 cysteine-rich, DPF motif domain containing 1 3.64274
RAP1GAP RAP1 GTPase activating protein 3.60631
IER3 immediate early response 3 3.56338
MAPK13 mitogen-activated protein kinase 13 3.53001
UBQLN2 ubiquilin 2 3.48866
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 3.4446
RTCA RNA 3'-terminal phosphate cyclase 3.43479
PHC2 polyhomeotic homolog 2 (Drosophila) 3.38962
ARHGAP12 Rho GTPase activating protein 12 3.38574
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 3.29916
EGR1 early growth response 1 3.29891
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 3.29307
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 3.27693
KIFBP kinesin family binding protein 3.17776
ASNS asparagine synthetase (glutamine-hydrolyzing) 3.15956
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 3.13653
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 3.08803
SARS1 seryl-tRNA synthetase 1 3.08234
TRIP4 thyroid hormone receptor interactor 4 3.01554
RALB v-ral simian leukemia viral oncogene homolog B 3.00808
EXOC1 exocyst complex component 1 2.98727
SNX16 sorting nexin 16 2.98284
CHIC2 cysteine-rich hydrophobic domain 2 2.95997
CLIP1 CAP-GLY domain containing linker protein 1 2.9385
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2.91515
UBE2A ubiquitin-conjugating enzyme E2A 2.91389
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 2.91257
MTCL1 microtubule crosslinking factor 1 2.8971
STXBP3 syntaxin binding protein 3 2.89276
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2.88667
IL4R interleukin 4 receptor 2.85635
REXO2 RNA exonuclease 2 2.84317
MOSPD1 motile sperm domain containing 1 2.83002
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.82387
PDCD6IP programmed cell death 6 interacting protein 2.81397
GTPBP2 GTP binding protein 2 2.81277
LOC128125814 uncharacterized LOC128125814 2.80511
AARS1 alanyl-tRNA synthetase 1 2.80283
RRAGC Ras-related GTP binding C 2.79368
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 2.74297
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 2.73191
STX12 syntaxin 12 2.72532
GRB10 growth factor receptor-bound protein 10 2.71731
NUP58 nucleoporin 58 2.70884
WDR44 WD repeat domain 44 2.70067
LOC127933115 uncharacterized LOC127933115 2.69429
ELOVL1 ELOVL fatty acid elongase 1 2.68423
COQ10B coenzyme Q10 homolog B (S. cerevisiae) 2.67114
PPP1R15A protein phosphatase 1, regulatory subunit 15A 2.65899
STX1A syntaxin 1A (brain) 2.64515
KIAA0319L KIAA0319-like 2.61379
GDI1 GDP dissociation inhibitor 1 2.61099
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 2.6018
MVP major vault protein 2.59937
ACOT9 acyl-CoA thioesterase 9 2.5968
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 2.59567
MIDEAS mitotic deacetylase associated SANT domain protein 2.59087
MINDY3 MINDY lysine 48 deubiquitinase 3 2.58877
RNF111 ring finger protein 111 2.58186
ATF3 activating transcription factor 3 2.57353
EPN2 epsin 2 2.55844
YARS1 tyrosyl-tRNA synthetase 1 2.55367
SH3GLB1 SH3-domain GRB2-like endophilin B1 2.54282
TERF2IP telomeric repeat binding factor 2, interacting protein 2.54197
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 2.5336
PELO pelota homolog (Drosophila) 2.53028
AOX1 aldehyde oxidase 1 2.52471
CCNDBP1 cyclin D-type binding-protein 1 2.51266
BCAR3 breast cancer anti-estrogen resistance 3 2.49863
TALDO1 transaldolase 1 2.48363
DUSP5 dual specificity phosphatase 5 2.4806
MGLL monoglyceride lipase 2.47251
PYGB phosphorylase, glycogen; brain 2.47043
ALAS1 5'-aminolevulinate synthase 1 2.46273
HDAC4 histone deacetylase 4 2.44568
CIB1 calcium and integrin binding 1 (calmyrin) 2.43509
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2.41522
PCDHB11 protocadherin beta 11 2.41479
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.41422
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 2.41343
PRSS3 protease, serine, 3 2.41333
CARS1 cysteinyl-tRNA synthetase 1 2.41208
FNTA farnesyltransferase, CAAX box, alpha 2.40723
EIF6 eukaryotic translation initiation factor 6 2.4052
MACF1 microtubule-actin crosslinking factor 1 2.40518
WDR13 WD repeat domain 13 2.40333
RHOC ras homolog family member C 2.40072
HKDC1 hexokinase domain containing 1 2.40005
ITPKC inositol-trisphosphate 3-kinase C 2.39624
CSRNP2 cysteine-serine-rich nuclear protein 2 2.39295
BECN1 beclin 1, autophagy related 2.38802
IFRD1 interferon-related developmental regulator 1 2.36736
PDE1A phosphodiesterase 1A, calmodulin-dependent 2.36678
FAM50A family with sequence similarity 50, member A 2.36674
ADAM9 ADAM metallopeptidase domain 9 2.36559
GFPT1 glutamine--fructose-6-phosphate transaminase 1 2.35854
EFL1 elongation factor like GTPase 1 2.35825
ETFB electron-transfer-flavoprotein, beta polypeptide 2.35752
KDM6B lysine (K)-specific demethylase 6B 2.35263
DUSP6 dual specificity phosphatase 6 2.34817
FRY furry homolog (Drosophila) 2.33821
WARS1 tryptophanyl-tRNA synthetase 1 2.33377
WSB2 WD repeat and SOCS box containing 2 2.33224
ATOSB atos homolog B 2.33116
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 2.32646
VWF von Willebrand factor 2.32026
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 2.31549
QSOX1 quiescin Q6 sulfhydryl oxidase 1 2.31452
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 2.30958
MAST4 microtubule associated serine/threonine kinase family member 4 2.30123
ZMYM2 zinc finger, MYM-type 2 2.29851
TM4SF1 transmembrane 4 L six family member 1 2.29405
BAZ1A bromodomain adjacent to zinc finger domain, 1A 2.29399
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 2.29272
ATXN2 ataxin 2 2.29115
YIPF4 Yip1 domain family, member 4 2.29059
GBE1 glucan (1,4-alpha-), branching enzyme 1 2.28462
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2.27778
GCLM glutamate-cysteine ligase, modifier subunit 2.27201
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 2.25998
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 2.25295
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 2.25287
PCNX1 pecanex 1 2.25201
TACC2 transforming, acidic coiled-coil containing protein 2 2.24132
RAB3B RAB3B, member RAS oncogene family 2.2365
ITGAV integrin, alpha V 2.23181
UBAP1 ubiquitin associated protein 1 2.22188
MYC v-myc avian myelocytomatosis viral oncogene homolog 2.2186
RPH3AL rabphilin 3A-like (without C2 domains) 2.20801
ETNK1 ethanolamine kinase 1 2.19627
VLDLR very low density lipoprotein receptor 2.18697
KCMF1 potassium channel modulatory factor 1 2.18318
MYH9 myosin, heavy chain 9, non-muscle 2.17793
SYNRG synergin, gamma 2.17698
PTK6 protein tyrosine kinase 6 2.17675
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 2.17467
ACVR1 activin A receptor, type I 2.17258
ACADVL acyl-CoA dehydrogenase, very long chain 2.17192
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) 2.17095
DENND4A DENN/MADD domain containing 4A 2.16944
S100A11 S100 calcium binding protein A11 2.16564
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 2.1633
LRRC41 leucine rich repeat containing 41 2.15925
TUT7 terminal uridylyl transferase 7 2.15461
GAK cyclin G associated kinase 2.15441
STBD1 starch binding domain 1 2.14505
ACTR10 actin-related protein 10 homolog (S. cerevisiae) 2.13947
AKR1C3 aldo-keto reductase family 1, member C3 2.13493
WDR47 WD repeat domain 47 2.11776
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 2.11763
JUN jun proto-oncogene 2.11739
AOC3 amine oxidase, copper containing 3 2.11115
MTX2 metaxin 2 2.11109
MARS1 methionyl-tRNA synthetase 1 2.10427
SKIC2 SKI2 subunit of superkiller complex 2.1034
CTC1 CTS telomere maintenance complex component 1 2.10324
NQO1 NAD(P)H dehydrogenase, quinone 1 2.10224
GPX2 glutathione peroxidase 2 2.09582
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 2.09556
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) 2.0941
MAP7D1 MAP7 domain containing 1 2.09391
MYOF myoferlin 2.09106
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 2.07585
RAB9A RAB9A, member RAS oncogene family 2.07489
ZNF750 zinc finger protein 750 2.05534
ANKRD12 ankyrin repeat domain 12 2.05033
ABHD18 abhydrolase domain containing 18 2.04731
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2.04312
YIPF1 Yip1 domain family, member 1 2.04204
SPRY4 sprouty homolog 4 (Drosophila) 2.036
ZEB2 zinc finger E-box binding homeobox 2 2.0359
BCL10 B-cell CLL/lymphoma 10 2.03335
TRIM8 tripartite motif containing 8 2.02871
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 2.02435
LAMB1 laminin, beta 1 2.02322
PPP1R12A protein phosphatase 1, regulatory subunit 12A 2.01879
CNKSR3 CNKSR family member 3 2.0169
NPC1 Niemann-Pick disease, type C1 2.0149
ZFAND5 zinc finger, AN1-type domain 5 2.00786
CTSA cathepsin A 2.00429
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 2.00203

decreased expression

Symbol Name Standardized Value
BIRC5 baculoviral IAP repeat containing 5 -5.50298
OIP5 Opa interacting protein 5 -4.84026
THAP11 THAP domain containing 11 -4.66868
CCNB1 cyclin B1 -4.62572
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -4.50715
TK1 thymidine kinase 1, soluble -4.49638
CDK1 cyclin-dependent kinase 1 -4.4588
MCM3 minichromosome maintenance complex component 3 -4.40591
CDC45 cell division cycle 45 -4.36361
CCNA2 cyclin A2 -4.34317
LBR lamin B receptor -4.31412
TOP2A topoisomerase (DNA) II alpha 170kDa -4.31256
CENPE centromere protein E, 312kDa -4.24391
KIF4A kinesin family member 4A -4.19275
KIF15 kinesin family member 15 -4.1398
NUSAP1 nucleolar and spindle associated protein 1 -4.06673
KIF20A kinesin family member 20A -4.03994
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -4.03983
KIFC1 kinesin family member C1 -4.02995
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -4.02724
UBE2C ubiquitin-conjugating enzyme E2C -4.01914
ZWINT ZW10 interacting kinetochore protein -4.0032
SPC25 SPC25, NDC80 kinetochore complex component -3.98509
CCNB2 cyclin B2 -3.97142
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.9313
PECR peroxisomal trans-2-enoyl-CoA reductase -3.92962
TMEM97 transmembrane protein 97 -3.92096
CDC20 cell division cycle 20 -3.88545
ASF1B anti-silencing function 1B histone chaperone -3.85586
ZDHHC6 zinc finger, DHHC-type containing 6 -3.82334
NUP85 nucleoporin 85kDa -3.81452
FEN1 flap structure-specific endonuclease 1 -3.7499
TRIP13 thyroid hormone receptor interactor 13 -3.72296
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -3.67789
SPAG5 sperm associated antigen 5 -3.67629
PSRC1 proline/serine-rich coiled-coil 1 -3.66127
HMMR hyaluronan-mediated motility receptor (RHAMM) -3.6356
PIMREG PICALM interacting mitotic regulator -3.63271
KIF11 kinesin family member 11 -3.62912
HAT1 histone acetyltransferase 1 -3.619
VRK1 vaccinia related kinase 1 -3.60742
AUNIP aurora kinase A and ninein interacting protein -3.573
RFC4 replication factor C (activator 1) 4, 37kDa -3.56585
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -3.52359
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -3.5212
GINS2 GINS complex subunit 2 (Psf2 homolog) -3.51524
GINS1 GINS complex subunit 1 (Psf1 homolog) -3.51461
AURKB aurora kinase B -3.49455
EXO1 exonuclease 1 -3.46214
HMGN2 high mobility group nucleosomal binding domain 2 -3.46207
PLK1 polo-like kinase 1 -3.44069
CDC25C cell division cycle 25C -3.44046
NEK2 NIMA-related kinase 2 -3.43115
HMGB2 high mobility group box 2 -3.4135
TRMT5 tRNA methyltransferase 5 -3.40188
POLR1A polymerase (RNA) I polypeptide A, 194kDa -3.34836
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -3.33708
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 -3.33603
SOAT2 sterol O-acyltransferase 2 -3.33385
TTK TTK protein kinase -3.31604
LMNB1 lamin B1 -3.30905
DHFR dihydrofolate reductase -3.30239
MCM10 minichromosome maintenance complex component 10 -3.28725
PAGR1 PAXIP1 associated glutamate-rich protein 1 -3.26087
NCAPD2 non-SMC condensin I complex, subunit D2 -3.25584
B4GAT1 beta-1,4-glucuronyltransferase 1 -3.23135
MCM5 minichromosome maintenance complex component 5 -3.22114
RPA3 replication protein A3, 14kDa -3.20434
HMGA2 high mobility group AT-hook 2 -3.19814
MNS1 meiosis-specific nuclear structural 1 -3.19642
NCAPH non-SMC condensin I complex, subunit H -3.18842
HACD3 3-hydroxyacyl-CoA dehydratase 3 -3.16375
SPDL1 spindle apparatus coiled-coil protein 1 -3.16172
MIS18A MIS18 kinetochore protein A -3.13497
RFC3 replication factor C (activator 1) 3, 38kDa -3.10754
PTTG1 pituitary tumor-transforming 1 -3.10065
PROM1 prominin 1 -3.06601
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -3.06268
SCARA3 scavenger receptor class A, member 3 -3.05953
CDC6 cell division cycle 6 -3.05781
MATK megakaryocyte-associated tyrosine kinase -3.05437
CDCA3 cell division cycle associated 3 -3.05326
BORA bora, aurora kinase A activator -3.03666
NCAPG2 non-SMC condensin II complex, subunit G2 -3.0346
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -3.01742
FN3KRP fructosamine 3 kinase related protein -3.01412
FANCC Fanconi anemia, complementation group C -3.01249
DTYMK deoxythymidylate kinase (thymidylate kinase) -2.99229
DEPDC1 DEP domain containing 1 -2.98774
H2AX H2A.X variant histone -2.95022
FANCI Fanconi anemia, complementation group I -2.94246
SESN1 sestrin 1 -2.92623
TPX2 TPX2, microtubule-associated -2.92125
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -2.89998
UXT ubiquitously-expressed, prefoldin-like chaperone -2.89546
PSIP1 PC4 and SFRS1 interacting protein 1 -2.89031
MCM7 minichromosome maintenance complex component 7 -2.8676
KIF18B kinesin family member 18B -2.8603
MKI67 marker of proliferation Ki-67 -2.86023
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -2.84716
IDI1 isopentenyl-diphosphate delta isomerase 1 -2.84502
HAUS7 HAUS augmin-like complex, subunit 7 -2.84376
CENPA centromere protein A -2.83507
H2AZ2 H2A.Z variant histone 2 -2.83273
STMN1 stathmin 1 -2.82694
CENPU centromere protein U -2.8169
SNRPA small nuclear ribonucleoprotein polypeptide A -2.81104
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa -2.78973
ELSPBP1 epididymal sperm binding protein 1 -2.7855
SRSF2 serine/arginine-rich splicing factor 2 -2.78536
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.7803
CENPI centromere protein I -2.77361
HJURP Holliday junction recognition protein -2.76073
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) -2.7593
NDC80 NDC80 kinetochore complex component -2.75588
CDCA4 cell division cycle associated 4 -2.71958
CDCA8 cell division cycle associated 8 -2.71575
RACGAP1 Rac GTPase activating protein 1 -2.71316
DSCC1 DNA replication and sister chromatid cohesion 1 -2.70128
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 -2.70001
MCM6 minichromosome maintenance complex component 6 -2.6952
CCNF cyclin F -2.69457
MRM2 mitochondrial rRNA methyltransferase 2 -2.69313
NUP107 nucleoporin 107kDa -2.68355
TEDC2 tubulin epsilon and delta complex 2 -2.68244
ATAD2 ATPase family, AAA domain containing 2 -2.6796
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme -2.6702
FOXM1 forkhead box M1 -2.66686
MSH2 mutS homolog 2 -2.64684
SRP9 signal recognition particle 9kDa -2.6455
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -2.63926
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -2.63674
DBF4 DBF4 zinc finger -2.63237
BRCA1 breast cancer 1, early onset -2.61181
CKS1B CDC28 protein kinase regulatory subunit 1B -2.60338
RFC2 replication factor C (activator 1) 2, 40kDa -2.5978
PRC1 protein regulator of cytokinesis 1 -2.59747
KIF22 kinesin family member 22 -2.58159
RRM1 ribonucleotide reductase M1 -2.57634
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -2.57333
DHCR7 7-dehydrocholesterol reductase -2.56899
KIF18A kinesin family member 18A -2.56327
ALG12 ALG12, alpha-1,6-mannosyltransferase -2.56314
MVD mevalonate (diphospho) decarboxylase -2.54199
CHAF1A chromatin assembly factor 1, subunit A (p150) -2.52097
PARP1 poly (ADP-ribose) polymerase 1 -2.51399
NUP155 nucleoporin 155kDa -2.51117
GINS3 GINS complex subunit 3 (Psf3 homolog) -2.50921
TBC1D31 TBC1 domain family, member 31 -2.50612
ERCC6L excision repair cross-complementation group 6-like -2.50236
JMJD6 jumonji domain containing 6 -2.49107
HADH hydroxyacyl-CoA dehydrogenase -2.48915
KIF23 kinesin family member 23 -2.48792
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) -2.48137
UGT2B10 UDP glucuronosyltransferase 2 family, polypeptide B10 -2.47607
ZWILCH zwilch kinetochore protein -2.46758
HIRIP3 HIRA interacting protein 3 -2.465
DUT deoxyuridine triphosphatase -2.46436
SLC17A2 solute carrier family 17, member 2 -2.46396
NLRP4 NLR family, pyrin domain containing 4 -2.45817
AURKA aurora kinase A -2.45569
TROAP trophinin associated protein -2.45406
PARPBP PARP1 binding protein -2.45002
ADI1 acireductone dioxygenase 1 -2.43898
CDO1 cysteine dioxygenase type 1 -2.42641
HMGN3 high mobility group nucleosomal binding domain 3 -2.4234
THOC1 THO complex 1 -2.41845
PGAM4 phosphoglycerate mutase family member 4 -2.40884
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.40795
TEX30 testis expressed 30 -2.40547
TM7SF2 transmembrane 7 superfamily member 2 -2.40251
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) -2.38857
BLM Bloom syndrome, RecQ helicase-like -2.37992
CSE1L CSE1 chromosome segregation 1-like (yeast) -2.37764
NELFCD negative elongation factor complex member C/D -2.37723
TTC13 tetratricopeptide repeat domain 13 -2.37672
RBMX RNA binding motif protein, X-linked -2.35841
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit -2.35832
CSRP2 cysteine and glycine-rich protein 2 -2.33965
WDR76 WD repeat domain 76 -2.339
CDC23 cell division cycle 23 -2.33266
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.32297
MSMO1 methylsterol monooxygenase 1 -2.32126
CENPM centromere protein M -2.31115
SLC2A4RG SLC2A4 regulator -2.30963
PBK PDZ binding kinase -2.30653
TDP1 tyrosyl-DNA phosphodiesterase 1 -2.29613
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -2.29568
CDK2 cyclin-dependent kinase 2 -2.29504
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -2.28924
PLK4 polo-like kinase 4 -2.28234
COG7 component of oligomeric golgi complex 7 -2.27743
NR2F6 nuclear receptor subfamily 2, group F, member 6 -2.27671
POLE polymerase (DNA directed), epsilon, catalytic subunit -2.27545
CEP131 centrosomal protein 131kDa -2.27173
PDZK1 PDZ domain containing 1 -2.27107
ELOVL6 ELOVL fatty acid elongase 6 -2.2674
CKAP2 cytoskeleton associated protein 2 -2.26619
RAD51AP1 RAD51 associated protein 1 -2.26457
HMGB1 high mobility group box 1 -2.26237
HSPD1 heat shock 60kDa protein 1 (chaperonin) -2.26192
KLHDC2 kelch domain containing 2 -2.25685
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -2.25635
IFITM3 interferon induced transmembrane protein 3 -2.25615
SLCO4C1 solute carrier organic anion transporter family, member 4C1 -2.25228
ACSM5 acyl-CoA synthetase medium-chain family member 5 -2.25054
FBXO5 F-box protein 5 -2.24686
PGM1 phosphoglucomutase 1 -2.24478
DCK deoxycytidine kinase -2.24415
RBBP7 retinoblastoma binding protein 7 -2.24413
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -2.22843
SHMT1 serine hydroxymethyltransferase 1 (soluble) -2.22781
SDF2L1 stromal cell-derived factor 2-like 1 -2.22648
PDK2 pyruvate dehydrogenase kinase, isozyme 2 -2.22599
MSH6 mutS homolog 6 -2.22253
CDT1 chromatin licensing and DNA replication factor 1 -2.22088
TECR trans-2,3-enoyl-CoA reductase -2.21967
FZD7 frizzled class receptor 7 -2.2119
CHAF1B chromatin assembly factor 1, subunit B (p60) -2.20935
PARD6A par-6 family cell polarity regulator alpha -2.2084
PGRMC1 progesterone receptor membrane component 1 -2.20837
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -2.20516
SKA1 spindle and kinetochore associated complex subunit 1 -2.20491
SQLE squalene epoxidase -2.19732
CDKN3 cyclin-dependent kinase inhibitor 3 -2.19395
GPS1 G protein pathway suppressor 1 -2.18745
BGLAP bone gamma-carboxyglutamate (gla) protein -2.18356
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -2.18162
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -2.17392
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 -2.17023
EIF3E eukaryotic translation initiation factor 3, subunit E -2.16533
RPS4Y1 ribosomal protein S4, Y-linked 1 -2.16524
IL11RA interleukin 11 receptor, alpha -2.16257
ADISSP adipose secreted signaling protein -2.15572
NPY1R neuropeptide Y receptor Y1 -2.15493
TM9SF2 transmembrane 9 superfamily member 2 -2.15456
KBTBD4 kelch repeat and BTB (POZ) domain containing 4 -2.15422
RUNX3 runt-related transcription factor 3 -2.1535
GGCT gamma-glutamylcyclotransferase -2.15288
PDIA6 protein disulfide isomerase family A, member 6 -2.1519
MELK maternal embryonic leucine zipper kinase -2.15044
MOCS3 molybdenum cofactor synthesis 3 -2.15038
KLHL26 kelch-like family member 26 -2.14967
POGLUT2 protein O-glucosyltransferase 2 -2.13241
MCM4 minichromosome maintenance complex component 4 -2.12898
IFITM1 interferon induced transmembrane protein 1 -2.12833
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.1214
FTCD formimidoyltransferase cyclodeaminase -2.1214
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.11996
GINS4 GINS complex subunit 4 (Sld5 homolog) -2.11777
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 -2.11713
CNPY3 canopy FGF signaling regulator 3 -2.11579
GALK1 galactokinase 1 -2.11261
MCRS1 microspherule protein 1 -2.11065
PTMA prothymosin, alpha -2.10517
NAE1 NEDD8 activating enzyme E1 subunit 1 -2.10517
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 -2.09216
GLO1 glyoxalase I -2.08989
DAPK1 death-associated protein kinase 1 -2.0866
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -2.08617
ERI3 ERI1 exoribonuclease family member 3 -2.08307
CBX5 chromobox homolog 5 -2.08224
RNF138 ring finger protein 138, E3 ubiquitin protein ligase -2.0819
MRPL11 mitochondrial ribosomal protein L11 -2.07924
NUCB2 nucleobindin 2 -2.07903
CENPN centromere protein N -2.07505
MYO19 myosin XIX -2.07112
TMEM106C transmembrane protein 106C -2.0687
CARHSP1 calcium regulated heat stable protein 1, 24kDa -2.06783
COMMD9 COMM domain containing 9 -2.06676
RBM23 RNA binding motif protein 23 -2.05743
FAM111A family with sequence similarity 111, member A -2.05539
ARHGAP11A Rho GTPase activating protein 11A -2.0551
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -2.05417
AKR1D1 aldo-keto reductase family 1, member D1 -2.04933
CER1 cerberus 1, DAN family BMP antagonist -2.04454
MGMT O-6-methylguanine-DNA methyltransferase -2.04454
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -2.04428
PHF10 PHD finger protein 10 -2.04123
SPOUT1 SPOUT domain containing methyltransferase 1 -2.04083
TRAIP TRAF interacting protein -2.03468
TMPO thymopoietin -2.02852
WRAP53 WD repeat containing, antisense to TP53 -2.02777
GLUL glutamate-ammonia ligase -2.02699
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.02399
HACD2 3-hydroxyacyl-CoA dehydratase 2 -2.02374
ERI2 ERI1 exoribonuclease family member 2 -2.0232
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) -2.00667
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -2.00471
KLHDC3 kelch domain containing 3 -2.00403
PARP2 poly (ADP-ribose) polymerase 2 -2.00143