| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | hp163 perturbation at 48 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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75 genes differentially expressed following the CRCGN015_HEPG2_48H:B13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPARG | peroxisome proliferator-activated receptor gamma | 3.92509 |
| ANO10 | anoctamin 10 | 3.86215 |
| ABHD4 | abhydrolase domain containing 4 | 3.70735 |
| TXNRD1 | thioredoxin reductase 1 | 3.2717 |
| PCDHB16 | protocadherin beta 16 | 3.198 |
| UGDH | UDP-glucose 6-dehydrogenase | 3.15568 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 3.08245 |
| NUP133 | nucleoporin 133kDa | 2.92816 |
| SMIM40 | small integral membrane protein 40 | 2.91085 |
| TLR4 | toll-like receptor 4 | 2.85355 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 2.85052 |
| SQSTM1 | sequestosome 1 | 2.80006 |
| BAD | BCL2-associated agonist of cell death | 2.79925 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2.7628 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.73278 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 2.6752 |
| KEAP1 | kelch-like ECH-associated protein 1 | 2.66368 |
| FAH | fumarylacetoacetate hydrolase (fumarylacetoacetase) | 2.65613 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 2.64247 |
| PRKCH | protein kinase C, eta | 2.5964 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 2.48868 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 2.44614 |
| NSMAF | neutral sphingomyelinase (N-SMase) activation associated factor | 2.33961 |
| MACROD1 | MACRO domain containing 1 | 2.32815 |
| ANXA7 | annexin A7 | 2.26076 |
| SLC16A7 | solute carrier family 16 (monocarboxylate transporter), member 7 | 2.23274 |
| CCDC169-SOHLH2 | CCDC169-SOHLH2 readthrough | 2.23157 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 2.21807 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | 2.20169 |
| RTN3 | reticulon 3 | 2.15892 |
| ELANE | elastase, neutrophil expressed | 2.15073 |
| MAP4 | microtubule-associated protein 4 | 2.11956 |
| FECH | ferrochelatase | 2.11707 |
| AZU1 | azurocidin 1 | 2.10213 |
| MTERF3 | mitochondrial transcription termination factor 3 | 2.09508 |
| DGUOK | deoxyguanosine kinase | 2.07792 |
| GSR | glutathione reductase | 2.06898 |
| RAP1GAP | RAP1 GTPase activating protein | 2.05156 |
| ZMAT5 | zinc finger, matrin-type 5 | 2.02349 |
| EXD2 | exonuclease 3'-5' domain containing 2 | 2.01677 |
| PTDSS1 | phosphatidylserine synthase 1 | 2.01061 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -6.51018 |
| C5 | complement component 5 | -5.23401 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | -4.41398 |
| CXADR | coxsackie virus and adenovirus receptor | -3.87749 |
| APOA2 | apolipoprotein A-II | -3.56067 |
| NRIP1 | nuclear receptor interacting protein 1 | -3.45131 |
| DCK | deoxycytidine kinase | -3.33994 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -3.29684 |
| A2M | alpha-2-macroglobulin | -3.1904 |
| FAIM | Fas apoptotic inhibitory molecule | -3.10062 |
| RHOB | ras homolog family member B | -3.05204 |
| IL17RB | interleukin 17 receptor B | -2.84423 |
| DUSP6 | dual specificity phosphatase 6 | -2.75751 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | -2.65412 |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 | -2.5674 |
| DIPK1A | divergent protein kinase domain 1A | -2.48394 |
| SLC66A2 | solute carrier family 66 member 2 | -2.4806 |
| CCNB1 | cyclin B1 | -2.37671 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -2.36935 |
| KLHDC2 | kelch domain containing 2 | -2.30869 |
| AURKB | aurora kinase B | -2.30251 |
| ACP5 | acid phosphatase 5, tartrate resistant | -2.27669 |
| SIDT1 | SID1 transmembrane family, member 1 | -2.22232 |
| CCL17 | chemokine (C-C motif) ligand 17 | -2.22085 |
| RBM15B | RNA binding motif protein 15B | -2.19904 |
| RND1 | Rho family GTPase 1 | -2.19255 |
| CLDN3 | claudin 3 | -2.1499 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -2.14613 |
| BIRC2 | baculoviral IAP repeat containing 2 | -2.05669 |
| HNRNPH2 | heterogeneous nuclear ribonucleoprotein H2 (H') | -2.04313 |
| COG2 | component of oligomeric golgi complex 2 | -2.0339 |
| RGS10 | regulator of G-protein signaling 10 | -2.02998 |
| NXPE4 | neurexophilin and PC-esterase domain family, member 4 | -2.0185 |
| CENPE | centromere protein E, 312kDa | -2.00707 |
