CRCGN015_HEPG2_48H:B16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description beta-naphthoflavone 100.0 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

617 genes differentially expressed following the CRCGN015_HEPG2_48H:B16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HMOX1 heme oxygenase 1 9.9793
ABHD4 abhydrolase domain containing 4 8.23308
CTSL cathepsin L 7.01274
SNX11 sorting nexin 11 6.56049
NUCB2 nucleobindin 2 6.3842
CEMIP2 cell migration inducing hyaluronidase 2 5.12166
TXNRD1 thioredoxin reductase 1 5.0216
MAPK13 mitogen-activated protein kinase 13 4.87443
GCLM glutamate-cysteine ligase, modifier subunit 4.67984
SQSTM1 sequestosome 1 4.44465
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 4.38811
VAT1 vesicle amine transport 1 4.26674
FHL2 four and a half LIM domains 2 4.21426
TRIB1 tribbles pseudokinase 1 4.20572
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 3.77236
REXO2 RNA exonuclease 2 3.69384
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 3.68198
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 3.61625
IER3 immediate early response 3 3.60998
NQO1 NAD(P)H dehydrogenase, quinone 1 3.60635
KEAP1 kelch-like ECH-associated protein 1 3.59992
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 3.53201
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 3.49333
NANOS3 nanos homolog 3 (Drosophila) 3.49307
FOSL1 FOS-like antigen 1 3.44836
SQOR sulfide quinone oxidoreductase 3.43428
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.41324
TALDO1 transaldolase 1 3.35706
BLCAP bladder cancer associated protein 3.32402
TRIB3 tribbles pseudokinase 3 3.30378
AMPD2 adenosine monophosphate deaminase 2 3.30263
IL4R interleukin 4 receptor 3.29951
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 3.26974
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 3.25397
RPAP3 RNA polymerase II associated protein 3 3.24189
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 3.21215
YIPF1 Yip1 domain family, member 1 3.16032
KDM3A lysine (K)-specific demethylase 3A 3.14307
COQ10B coenzyme Q10 homolog B (S. cerevisiae) 3.13387
ALAS1 5'-aminolevulinate synthase 1 3.11115
CDPF1 cysteine-rich, DPF motif domain containing 1 3.1089
LRP10 low density lipoprotein receptor-related protein 10 3.1059
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 3.10201
GRB10 growth factor receptor-bound protein 10 3.09004
ZFP36 ZFP36 ring finger protein 3.06006
RCN1 reticulocalbin 1, EF-hand calcium binding domain 3.04798
TUBB6 tubulin, beta 6 class V 3.02601
UNKL unkempt family zinc finger-like 3.01681
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 2.97
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 2.91557
PIR pirin (iron-binding nuclear protein) 2.90385
PRDX1 peroxiredoxin 1 2.89478
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 2.86869
TSLIG3A tRNA splicing ligase complex subunit 3A 2.86468
TTC4 tetratricopeptide repeat domain 4 2.84555
TMED3 transmembrane emp24 protein transport domain containing 3 2.84197
UBAP1 ubiquitin associated protein 1 2.81127
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like 2.81046
BATF basic leucine zipper transcription factor, ATF-like 2.80121
RALB v-ral simian leukemia viral oncogene homolog B 2.79894
PELO pelota homolog (Drosophila) 2.7923
ZDHHC18 zinc finger, DHHC-type containing 18 2.78398
TERF2IP telomeric repeat binding factor 2, interacting protein 2.73077
HEBP1 heme binding protein 1 2.68605
MTCL1 microtubule crosslinking factor 1 2.68247
PCDHB16 protocadherin beta 16 2.68205
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 2.67904
SLC35F2 solute carrier family 35, member F2 2.67596
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 2.66298
SUMF2 sulfatase modifying factor 2 2.66227
BYSL bystin-like 2.66128
BAG2 BCL2-associated athanogene 2 2.6449
NSF N-ethylmaleimide-sensitive factor 2.63856
ADM adrenomedullin 2.62019
TRIM16 tripartite motif containing 16 2.61426
JUN jun proto-oncogene 2.58066
TMEM127 transmembrane protein 127 2.57555
UGDH UDP-glucose 6-dehydrogenase 2.5701
DHRS7 dehydrogenase/reductase (SDR family) member 7 2.56316
DUSP6 dual specificity phosphatase 6 2.53579
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 2.53522
UTP11 UTP11 small subunit processome component 2.53471
NUP58 nucleoporin 58 2.533
PROCR protein C receptor, endothelial 2.53119
EGR1 early growth response 1 2.52649
WDR3 WD repeat domain 3 2.52296
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 2.51248
KLC3 kinesin light chain 3 2.51248
HSPB8 heat shock 22kDa protein 8 2.50922
STX1A syntaxin 1A (brain) 2.50659
RPN1 ribophorin I 2.5042
EIF6 eukaryotic translation initiation factor 6 2.49467
TRIP4 thyroid hormone receptor interactor 4 2.49399
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 2.48521
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 2.4729
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 2.4518
SLC67A1 solute carrier family 67 member 1 2.44996
RAB5IF RAB5 interacting factor 2.44945
OSGIN1 oxidative stress induced growth inhibitor 1 2.44694
INPP1 inositol polyphosphate-1-phosphatase 2.44645
FECH ferrochelatase 2.44644
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 2.43194
RHOF ras homolog family member F (in filopodia) 2.42983
PPARG peroxisome proliferator-activated receptor gamma 2.42762
CRYBG3 beta-gamma crystallin domain containing 3 2.42721
MCFD2 multiple coagulation factor deficiency 2 2.42197
PFN2 profilin 2 2.40168
TOMM34 translocase of outer mitochondrial membrane 34 2.40152
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 2.39897
TSKU tsukushi, small leucine rich proteoglycan 2.39644
HSPA1B heat shock 70kDa protein 1B 2.38367
RLF rearranged L-myc fusion 2.38228
YARS1 tyrosyl-tRNA synthetase 1 2.37632
PARL presenilin associated, rhomboid-like 2.37351
ETFB electron-transfer-flavoprotein, beta polypeptide 2.359
ZNF593 zinc finger protein 593 2.35644
FASTKD5 FAST kinase domains 5 2.34681
CDA cytidine deaminase 2.33182
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 2.33071
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 2.31175
RAP1GAP RAP1 GTPase activating protein 2.29654
ALG3 ALG3, alpha-1,3- mannosyltransferase 2.28613
EHD4 EH-domain containing 4 2.27888
SEC61G Sec61 gamma subunit 2.2788
CBX1 chromobox homolog 1 2.27732
LOX lysyl oxidase 2.2759
EMC7 ER membrane protein complex subunit 7 2.26279
KIAA0319L KIAA0319-like 2.25859
CHIC2 cysteine-rich hydrophobic domain 2 2.25515
CHUK conserved helix-loop-helix ubiquitous kinase 2.25272
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1 2.24741
RPP40 ribonuclease P/MRP 40kDa subunit 2.24528
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.24161
NAV3 neuron navigator 3 2.24133
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 2.23801
AKR1C3 aldo-keto reductase family 1, member C3 2.22964
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 2.21863
DAD1 defender against cell death 1 2.21815
MED8 mediator complex subunit 8 2.21438
IGFBP4 insulin-like growth factor binding protein 4 2.20523
MOK MOK protein kinase 2.20409
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 2.20372
EMC3 ER membrane protein complex subunit 3 2.20278
CYB5R1 cytochrome b5 reductase 1 2.19973
BATF3 basic leucine zipper transcription factor, ATF-like 3 2.19375
NSFL1C NSFL1 (p97) cofactor (p47) 2.19367
ELOVL1 ELOVL fatty acid elongase 1 2.19088
ALG11 ALG11, alpha-1,2-mannosyltransferase 2.19064
GBE1 glucan (1,4-alpha-), branching enzyme 1 2.18565
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 2.18342
POPDC3 popeye domain containing 3 2.17983
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 2.17419
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 2.16945
SPRR2B small proline-rich protein 2B 2.16767
EBI3 Epstein-Barr virus induced 3 2.16449
LHFPL2 lipoma HMGIC fusion partner-like 2 2.15933
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase 2.1503
SLC38A6 solute carrier family 38, member 6 2.14681
NRDC nardilysin convertase 2.14572
EBNA1BP2 EBNA1 binding protein 2 2.142
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 2.13955
REEP5 receptor accessory protein 5 2.13946
BECN1 beclin 1, autophagy related 2.13857
LSG1 large 60S subunit nuclear export GTPase 1 2.13421
CDK5RAP2 CDK5 regulatory subunit associated protein 2 2.1315
MBD1 methyl-CpG binding domain protein 1 2.12896
MFSD1 major facilitator superfamily domain containing 1 2.12355
GLRX glutaredoxin (thioltransferase) 2.12296
AARSD1 alanyl-tRNA synthetase domain containing 1 2.12177
RIOX2 ribosomal oxygenase 2 2.11707
AATF apoptosis antagonizing transcription factor 2.11689
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 2.11535
F2RL1 coagulation factor II (thrombin) receptor-like 1 2.11144
ADAM9 ADAM metallopeptidase domain 9 2.10812
NFE2L1 nuclear factor, erythroid 2-like 1 2.09141
RAB9A RAB9A, member RAS oncogene family 2.07691
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa 2.07277
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.06497
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma 2.06408
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae) 2.06274
FOSB FBJ murine osteosarcoma viral oncogene homolog B 2.06194
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 2.06163
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 2.0603
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 2.04397
SCPEP1 serine carboxypeptidase 1 2.04167
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11 2.04154
MYC v-myc avian myelocytomatosis viral oncogene homolog 2.04011
THUMPD2 THUMP domain containing 2 2.0359
UPP1 uridine phosphorylase 1 2.03552
BLVRB biliverdin reductase B 2.03496
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 2.03105
PRDM4 PR domain containing 4 2.02848
SUCO SUN domain containing ossification factor 2.02737
SDF2 stromal cell-derived factor 2 2.02653
STC2 stanniocalcin 2 2.02026
PPCDC phosphopantothenoylcysteine decarboxylase 2.01956
MAP7D1 MAP7 domain containing 1 2.01581
PCDHGA5 protocadherin gamma subfamily A, 5 2.01172

decreased expression

Symbol Name Standardized Value
CXADR coxsackie virus and adenovirus receptor -6.61706
APOH apolipoprotein H (beta-2-glycoprotein I) -5.83538
C5 complement component 5 -5.64781
STMN1 stathmin 1 -5.04543
KIF20A kinesin family member 20A -4.59948
TF transferrin -4.59292
IL17RB interleukin 17 receptor B -4.35906
CDK1 cyclin-dependent kinase 1 -4.18805
APOA2 apolipoprotein A-II -4.13064
KIF15 kinesin family member 15 -4.1277
EIF5 eukaryotic translation initiation factor 5 -3.98841
NUSAP1 nucleolar and spindle associated protein 1 -3.93589
MCM7 minichromosome maintenance complex component 7 -3.89021
FBF1 Fas (TNFRSF6) binding factor 1 -3.85124
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 -3.81196
BIRC5 baculoviral IAP repeat containing 5 -3.80501
ASF1B anti-silencing function 1B histone chaperone -3.74708
RNF130 ring finger protein 130 -3.73178
TOP2A topoisomerase (DNA) II alpha 170kDa -3.68088
HMGB2 high mobility group box 2 -3.67593
GINS1 GINS complex subunit 1 (Psf1 homolog) -3.66434
CCNA2 cyclin A2 -3.66164
KLHDC2 kelch domain containing 2 -3.65074
FOXM1 forkhead box M1 -3.64195
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 -3.64133
PROM1 prominin 1 -3.58108
HMGA2 high mobility group AT-hook 2 -3.47491
COG7 component of oligomeric golgi complex 7 -3.45124
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -3.44952
HGFAC HGF activator -3.44177
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -3.41941
YME1L1 YME1-like 1 ATPase -3.4089
SRP9 signal recognition particle 9kDa -3.36406
HAT1 histone acetyltransferase 1 -3.35793
CCNB1 cyclin B1 -3.35787
CPB2 carboxypeptidase B2 (plasma) -3.3507
NDC80 NDC80 kinetochore complex component -3.33458
GNAS GNAS complex locus -3.33249
CCNB2 cyclin B2 -3.33027
IFITM3 interferon induced transmembrane protein 3 -3.31256
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -3.30733
KIF4A kinesin family member 4A -3.30291
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 -3.29494
VAV3 vav 3 guanine nucleotide exchange factor -3.28
FANCI Fanconi anemia, complementation group I -3.2736
NCAPD2 non-SMC condensin I complex, subunit D2 -3.26879
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -3.22995
PSRC1 proline/serine-rich coiled-coil 1 -3.22423
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) -3.21511
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 -3.215
TPX2 TPX2, microtubule-associated -3.21268
BIRC2 baculoviral IAP repeat containing 2 -3.20608
H2AZ2 H2A.Z variant histone 2 -3.19934
AURKB aurora kinase B -3.19833
CDCA8 cell division cycle associated 8 -3.1545
PBLD phenazine biosynthesis-like protein domain containing -3.14818
KIFC1 kinesin family member C1 -3.1469
TRMT5 tRNA methyltransferase 5 -3.14673
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 -3.13647
RBMX RNA binding motif protein, X-linked -3.10432
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -3.09658
NEK2 NIMA-related kinase 2 -3.08952
HMGN2 high mobility group nucleosomal binding domain 2 -3.08852
MNS1 meiosis-specific nuclear structural 1 -3.08165
TRIP13 thyroid hormone receptor interactor 13 -3.07919
KIF11 kinesin family member 11 -3.06438
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -3.04773
ASGR1 asialoglycoprotein receptor 1 -3.0395
MIS18A MIS18 kinetochore protein A -3.03425
MXD3 MAX dimerization protein 3 -3.0298
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -3.02022
HADH hydroxyacyl-CoA dehydrogenase -3.0058
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -3.00052
MATK megakaryocyte-associated tyrosine kinase -2.99333
PYGL phosphorylase, glycogen, liver -2.9782
MCM4 minichromosome maintenance complex component 4 -2.97076
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 -2.96846
LECT2 leukocyte cell-derived chemotaxin 2 -2.9626
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -2.96121
PIMREG PICALM interacting mitotic regulator -2.95949
HMMR hyaluronan-mediated motility receptor (RHAMM) -2.93904
CENPE centromere protein E, 312kDa -2.93603
CARHSP1 calcium regulated heat stable protein 1, 24kDa -2.92732
PECR peroxisomal trans-2-enoyl-CoA reductase -2.92254
CDC20 cell division cycle 20 -2.91661
SLC17A2 solute carrier family 17, member 2 -2.90761
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -2.90564
LUM lumican -2.90088
QARS1 glutaminyl-tRNA synthetase 1 -2.88901
G6PC1 glucose-6-phosphatase catalytic subunit 1 -2.87535
CHAF1A chromatin assembly factor 1, subunit A (p150) -2.85492
NCK1 NCK adaptor protein 1 -2.85136
FGA fibrinogen alpha chain -2.85065
ADH6 alcohol dehydrogenase 6 (class V) -2.84648
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.84586
CALM1 calmodulin 1 (phosphorylase kinase, delta) -2.84281
CLMN calmin (calponin-like, transmembrane) -2.83417
RNF125 ring finger protein 125, E3 ubiquitin protein ligase -2.82786
VRK1 vaccinia related kinase 1 -2.82617
PRODH2 proline dehydrogenase (oxidase) 2 -2.8198
PLP1 proteolipid protein 1 -2.81854
PCNA proliferating cell nuclear antigen -2.81517
MCM3 minichromosome maintenance complex component 3 -2.813
ATAD2 ATPase family, AAA domain containing 2 -2.80605
CX3CL1 chemokine (C-X3-C motif) ligand 1 -2.79894
FGL1 fibrinogen-like 1 -2.79567
SESN1 sestrin 1 -2.79233
PCDHB12 protocadherin beta 12 -2.78423
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.78271
SRSF4 serine/arginine-rich splicing factor 4 -2.77871
FEN1 flap structure-specific endonuclease 1 -2.77164
C3 complement component 3 -2.76848
FCHSD2 FCH and double SH3 domains 2 -2.76138
C8A complement component 8, alpha polypeptide -2.75916
TBC1D31 TBC1 domain family, member 31 -2.73869
NCAPH non-SMC condensin I complex, subunit H -2.73083
LAX1 lymphocyte transmembrane adaptor 1 -2.72186
FABP1 fatty acid binding protein 1, liver -2.71902
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 -2.71606
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) -2.71181
CYP3A7-CYP3A51P CYP3A7-CYP3A51P readthrough -2.70428
CENPA centromere protein A -2.70258
NT5DC2 5'-nucleotidase domain containing 2 -2.69722
SGPP2 sphingosine-1-phosphate phosphatase 2 -2.691
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 -2.68626
HMGN1 high mobility group nucleosome binding domain 1 -2.68406
DHFR dihydrofolate reductase -2.67689
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.67373
CALM2 calmodulin 2 (phosphorylase kinase, delta) -2.67158
PTTG1 pituitary tumor-transforming 1 -2.67111
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa -2.64637
SKI SKI proto-oncogene -2.64206
FTCD formimidoyltransferase cyclodeaminase -2.63129
PADI2 peptidyl arginine deiminase, type II -2.63107
NXPE4 neurexophilin and PC-esterase domain family, member 4 -2.62864
C8B complement component 8, beta polypeptide -2.6182
ITGB8 integrin, beta 8 -2.60672
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -2.59737
NUP85 nucleoporin 85kDa -2.59721
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -2.59686
NCAPG2 non-SMC condensin II complex, subunit G2 -2.5953
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.5924
RACGAP1 Rac GTPase activating protein 1 -2.58486
NONO non-POU domain containing, octamer-binding -2.5841
TK1 thymidine kinase 1, soluble -2.57209
KIF22 kinesin family member 22 -2.57051
ZMYM3 zinc finger, MYM-type 3 -2.56672
CDK19 cyclin-dependent kinase 19 -2.55712
GDI2 GDP dissociation inhibitor 2 -2.55712
OIP5 Opa interacting protein 5 -2.55634
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -2.55605
A2M alpha-2-macroglobulin -2.55131
CDC25C cell division cycle 25C -2.55087
PLXND1 plexin D1 -2.53917
YPEL1 yippee-like 1 (Drosophila) -2.53364
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -2.53283
AKR1D1 aldo-keto reductase family 1, member D1 -2.52667
MAT2B methionine adenosyltransferase II, beta -2.52568
KCTD11 potassium channel tetramerization domain containing 11 -2.52445
UBE2C ubiquitin-conjugating enzyme E2C -2.52358
FUZ fuzzy planar cell polarity protein -2.52294
CNTRL centriolin -2.51969
PACS2 phosphofurin acidic cluster sorting protein 2 -2.51917
BRCA1 breast cancer 1, early onset -2.51763
PAH phenylalanine hydroxylase -2.51263
PLK4 polo-like kinase 4 -2.50735
CDCA4 cell division cycle associated 4 -2.506
CFHR3 complement factor H-related 3 -2.50242
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 -2.50164
PRR11 proline rich 11 -2.50074
PROS1 protein S (alpha) -2.49555
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1 -2.49549
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.49221
H1-10 H1.10 linker histone -2.49042
AGGF1 angiogenic factor with G patch and FHA domains 1 -2.48933
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -2.4881
OTC ornithine carbamoyltransferase -2.48285
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa -2.47813
HSPD1 heat shock 60kDa protein 1 (chaperonin) -2.47568
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.47107
CDC45 cell division cycle 45 -2.47038
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae) -2.46981
RFC3 replication factor C (activator 1) 3, 38kDa -2.46965
LPAR6 lysophosphatidic acid receptor 6 -2.46825
RFC2 replication factor C (activator 1) 2, 40kDa -2.46181
HPR haptoglobin-related protein -2.46051
CACNB2 calcium channel, voltage-dependent, beta 2 subunit -2.46031
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -2.459
RFC4 replication factor C (activator 1) 4, 37kDa -2.45688
CCT8 chaperonin containing TCP1, subunit 8 (theta) -2.45319
AUNIP aurora kinase A and ninein interacting protein -2.44908
ZWILCH zwilch kinetochore protein -2.44273
PGM1 phosphoglucomutase 1 -2.43281
MCM5 minichromosome maintenance complex component 5 -2.43237
SHMT1 serine hydroxymethyltransferase 1 (soluble) -2.43141
ERN2 endoplasmic reticulum to nucleus signaling 2 -2.42998
CLSTN3 calsyntenin 3 -2.42497
YBX2 Y box binding protein 2 -2.42324
AMBP alpha-1-microglobulin/bikunin precursor -2.41966
PM20D1 peptidase M20 domain containing 1 -2.41524
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 -2.41507
CDCA3 cell division cycle associated 3 -2.39569
CTNND2 catenin (cadherin-associated protein), delta 2 -2.39258
CDK2 cyclin-dependent kinase 2 -2.38964
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 -2.38843
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -2.38739
BCHE butyrylcholinesterase -2.38337
PTMA prothymosin, alpha -2.38139
PROZ protein Z, vitamin K-dependent plasma glycoprotein -2.38073
TACC3 transforming, acidic coiled-coil containing protein 3 -2.37919
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase -2.3772
E2F1 E2F transcription factor 1 -2.37497
ELAC1 elaC ribonuclease Z 1 -2.37456
AFM afamin -2.37275
SENP7 SUMO1/sentrin specific peptidase 7 -2.372
C4BPA complement component 4 binding protein, alpha -2.37198
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 -2.37181
PIGV phosphatidylinositol glycan anchor biosynthesis, class V -2.36945
KNG1 kininogen 1 -2.36918
ONECUT1 one cut homeobox 1 -2.36899
PRC1 protein regulator of cytokinesis 1 -2.36259
PCSK1 proprotein convertase subtilisin/kexin type 1 -2.36254
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 -2.3605
ASGR2 asialoglycoprotein receptor 2 -2.35594
MRNIP MRN complex interacting protein -2.34811
KDM1A lysine (K)-specific demethylase 1A -2.34556
IGF2 insulin-like growth factor 2 -2.33904
CKS1B CDC28 protein kinase regulatory subunit 1B -2.33541
CHAF1B chromatin assembly factor 1, subunit B (p60) -2.33365
CEP57 centrosomal protein 57kDa -2.33317
DMAC2L distal membrane arm assembly component 2 like -2.3299
GYS2 glycogen synthase 2 (liver) -2.32269
ZG16 zymogen granule protein 16 -2.31997
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 -2.31646
TROAP trophinin associated protein -2.3159
CKAP5 cytoskeleton associated protein 5 -2.31575
H2AZ1 H2A.Z variant histone 1 -2.31436
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 -2.31325
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -2.30584
PLG plasminogen -2.30108
DSCC1 DNA replication and sister chromatid cohesion 1 -2.30065
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.29021
DPF1 D4, zinc and double PHD fingers family 1 -2.28971
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) -2.28259
GRIA2 glutamate receptor, ionotropic, AMPA 2 -2.27924
DCAF16 DDB1 and CUL4 associated factor 16 -2.2756
PCNT pericentrin -2.27439
RAD21 RAD21 homolog (S. pombe) -2.27405
OLFM4 olfactomedin 4 -2.27386
COL1A2 collagen, type I, alpha 2 -2.27259
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta -2.27089
KCNK10 potassium channel, two pore domain subfamily K, member 10 -2.26979
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2) -2.26966
SPATA6 spermatogenesis associated 6 -2.26724
HMGB1 high mobility group box 1 -2.26261
GTSE1 G-2 and S-phase expressed 1 -2.26038
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 -2.25884
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -2.25868
SNRPA small nuclear ribonucleoprotein polypeptide A -2.25711
HP1BP3 heterochromatin protein 1, binding protein 3 -2.25669
MMP7 matrix metallopeptidase 7 -2.25645
ZWINT ZW10 interacting kinetochore protein -2.25423
CP ceruloplasmin (ferroxidase) -2.25322
S100A1 S100 calcium binding protein A1 -2.24725
RIPPLY3 ripply transcriptional repressor 3 -2.24488
RAB26 RAB26, member RAS oncogene family -2.24244
RAB4A RAB4A, member RAS oncogene family -2.24225
CFAP298 cilia and flagella associated protein 298 -2.24183
ZNF33B zinc finger protein 33B -2.24002
SLC38A4 solute carrier family 38, member 4 -2.23875
CLASP2 cytoplasmic linker associated protein 2 -2.23239
S100A4 S100 calcium binding protein A4 -2.23121
CCHCR1 coiled-coil alpha-helical rod protein 1 -2.23114
EPHX2 epoxide hydrolase 2, cytoplasmic -2.22949
CLASRP CLK4-associating serine/arginine rich protein -2.22512
DUT deoxyuridine triphosphatase -2.22506
PRKACB protein kinase, cAMP-dependent, catalytic, beta -2.22242
SEPHS1 selenophosphate synthetase 1 -2.22191
IFITM1 interferon induced transmembrane protein 1 -2.22065
B4GAT1 beta-1,4-glucuronyltransferase 1 -2.21949
APOC3 apolipoprotein C-III -2.21928
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 -2.21765
CAMTA1 calmodulin binding transcription activator 1 -2.21757
PCP4 Purkinje cell protein 4 -2.21169
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43 -2.2111
ELSPBP1 epididymal sperm binding protein 1 -2.21073
CATSPERB catsper channel auxiliary subunit beta -2.21045
ITM2C integral membrane protein 2C -2.20868
APOF apolipoprotein F -2.2042
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.194
DEPDC1 DEP domain containing 1 -2.19293
ACSM3 acyl-CoA synthetase medium-chain family member 3 -2.1888
PLN phospholamban -2.18425
KNTC1 kinetochore associated 1 -2.18283
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -2.18274
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 -2.18091
SNX10 sorting nexin 10 -2.17572
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -2.17549
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 -2.17299
POLR1F RNA polymerase I subunit F -2.17219
USP2 ubiquitin specific peptidase 2 -2.16989
SQLE squalene epoxidase -2.16955
FANCA Fanconi anemia, complementation group A -2.16954
RCAN3 RCAN family member 3 -2.16934
NPY1R neuropeptide Y receptor Y1 -2.16887
ANKRD26 ankyrin repeat domain 26 -2.1652
FGB fibrinogen beta chain -2.16376
RPA3 replication protein A3, 14kDa -2.16318
CXCR6 chemokine (C-X-C motif) receptor 6 -2.16182
EGFL8 EGF-like-domain, multiple 8 -2.16099
MAP2K6 mitogen-activated protein kinase kinase 6 -2.15646
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -2.15236
MACROH2A2 macroH2A.2 histone -2.15183
IGFBP7 insulin-like growth factor binding protein 7 -2.15067
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -2.15022
ZNF287 zinc finger protein 287 -2.14869
ZNF37A zinc finger protein 37A -2.1474
PON1 paraoxonase 1 -2.1462
FXYD6-FXYD2 FXYD6-FXYD2 readthrough -2.14335
ADGRG6 adhesion G protein-coupled receptor G6 -2.14276
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 -2.1427
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 -2.14173
DCK deoxycytidine kinase -2.13961
CCDC71 coiled-coil domain containing 71 -2.13783
RPL3 ribosomal protein L3 -2.13762
NUP107 nucleoporin 107kDa -2.13735
ZNF573 zinc finger protein 573 -2.13616
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) -2.13606
MKI67 marker of proliferation Ki-67 -2.13122
JAKMIP2 janus kinase and microtubule interacting protein 2 -2.13058
AGBL2 ATP/GTP binding protein-like 2 -2.12999
CLCA1 chloride channel accessory 1 -2.12969
PLSCR4 phospholipid scramblase 4 -2.12846
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -2.12738
ERBB2 erb-b2 receptor tyrosine kinase 2 -2.12636
TM4SF5 transmembrane 4 L six family member 5 -2.12517
CNPY3-GNMT CNPY3-GNMT readthrough -2.12488
DONSON downstream neighbor of SON -2.12242
SRD5A3 steroid 5 alpha-reductase 3 -2.12011
MGP matrix Gla protein -2.11611
SLC44A1 solute carrier family 44 (choline transporter), member 1 -2.11469
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) -2.11464
ZKSCAN3 zinc finger with KRAB and SCAN domains 3 -2.11102
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 -2.10978
UGT2B10 UDP glucuronosyltransferase 2 family, polypeptide B10 -2.10975
NTM neurotrimin -2.10957
NFYB nuclear transcription factor Y, beta -2.10672
RIDA reactive intermediate imine deaminase A homolog -2.1063
DHRS1 dehydrogenase/reductase (SDR family) member 1 -2.10408
ONECUT2 one cut homeobox 2 -2.10341
ZNF248 zinc finger protein 248 -2.10294
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 -2.09638
PRKCB protein kinase C, beta -2.09551
CFHR5 complement factor H-related 5 -2.09172
ZNF22 zinc finger protein 22 -2.09061
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 -2.09057
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -2.08917
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 -2.08903
PDXK pyridoxal (pyridoxine, vitamin B6) kinase -2.08777
TM7SF2 transmembrane 7 superfamily member 2 -2.08742
ZMYND10 zinc finger, MYND-type containing 10 -2.08466
GDF7 growth differentiation factor 7 -2.08285
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1 -2.07996
MCM6 minichromosome maintenance complex component 6 -2.07888
HELLS helicase, lymphoid-specific -2.07563
NPY5R neuropeptide Y receptor Y5 -2.07261
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase -2.07233
A1CF APOBEC1 complementation factor -2.07217
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 -2.07131
MAPK8 mitogen-activated protein kinase 8 -2.0686
ZBTB14 zinc finger and BTB domain containing 14 -2.06656
C1RL complement component 1, r subcomponent-like -2.06633
FBL fibrillarin -2.06619
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 -2.06576
AGXT alanine-glyoxylate aminotransferase -2.06443
NLRP4 NLR family, pyrin domain containing 4 -2.06433
PHF13 PHD finger protein 13 -2.06385
GFRA1 GDNF family receptor alpha 1 -2.06313
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 -2.06147
IDI1 isopentenyl-diphosphate delta isomerase 1 -2.05991
F9 coagulation factor IX -2.05565
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide -2.05077
PDE4B phosphodiesterase 4B, cAMP-specific -2.05058
IPO8 importin 8 -2.05036
PHF10 PHD finger protein 10 -2.05034
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) -2.04964
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 -2.04915
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) -2.048
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 -2.04703
GYG2 glycogenin 2 -2.04658
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 -2.04342
HAO2 hydroxyacid oxidase 2 (long chain) -2.04286
NAGA N-acetylgalactosaminidase, alpha- -2.04137
GTF2I general transcription factor IIi -2.03881
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 -2.03575
CA8 carbonic anhydrase VIII -2.03475
FANCC Fanconi anemia, complementation group C -2.0334
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 -2.0331
ORAI2 ORAI calcium release-activated calcium modulator 2 -2.03284
NR3C2 nuclear receptor subfamily 3, group C, member 2 -2.02967
SPC25 SPC25, NDC80 kinetochore complex component -2.02852
DRC3 dynein regulatory complex subunit 3 -2.02829
PLXNB1 plexin B1 -2.02731
PDE3B phosphodiesterase 3B, cGMP-inhibited -2.02696
LEFTY1 left-right determination factor 1 -2.0268
LOC124907012 endogenous retrovirus group K member 7 Env polyprotein-like -2.02582
PEDS1 plasmanylethanolamine desaturase 1 -2.02427
PARD6A par-6 family cell polarity regulator alpha -2.02422
S100B S100 calcium binding protein B -2.02299
CDT1 chromatin licensing and DNA replication factor 1 -2.02
GCDH glutaryl-CoA dehydrogenase -2.00697
NBPF10 neuroblastoma breakpoint family, member 10 -2.00695
HMBOX1 homeobox containing 1 -2.00682
TEDC2 tubulin epsilon and delta complex 2 -2.00505
HNRNPR heterogeneous nuclear ribonucleoprotein R -2.00478
HAMP hepcidin antimicrobial peptide -2.00408
HSPB1 heat shock 27kDa protein 1 -2.00314
SYNE2 spectrin repeat containing, nuclear envelope 2 -2.00306
SIDT1 SID1 transmembrane family, member 1 -2.00157