CRCGN015_HEPG2_48H:B17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description beta-naphthoflavone 33.33 um perturbation at 48 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

604 genes differentially expressed following the CRCGN015_HEPG2_48H:B17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HMOX1 heme oxygenase 1 10.0
ABHD4 abhydrolase domain containing 4 8.364
CTSL cathepsin L 6.74085
SQOR sulfide quinone oxidoreductase 6.3215
MAPK13 mitogen-activated protein kinase 13 5.19757
EPN2 epsin 2 4.88262
GSTZ1 glutathione S-transferase zeta 1 4.84645
NUCB2 nucleobindin 2 4.72275
TXNRD1 thioredoxin reductase 1 4.7151
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 4.64905
FHL2 four and a half LIM domains 2 4.3529
TRIB1 tribbles pseudokinase 1 4.31985
SQSTM1 sequestosome 1 4.16335
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 4.0637
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 3.98025
REXO2 RNA exonuclease 2 3.96196
GCLM glutamate-cysteine ligase, modifier subunit 3.91245
FOSL1 FOS-like antigen 1 3.8685
PROCR protein C receptor, endothelial 3.84825
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 3.8189
ZFP36 ZFP36 ring finger protein 3.7159
CDA cytidine deaminase 3.53335
BYSL bystin-like 3.51655
CEMIP2 cell migration inducing hyaluronidase 2 3.4163
PELO pelota homolog (Drosophila) 3.4084
CDK5RAP2 CDK5 regulatory subunit associated protein 2 3.3888
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 3.3155
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 3.31075
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 3.27705
VAT1 vesicle amine transport 1 3.25165
UNKL unkempt family zinc finger-like 3.2417
TREM1 triggering receptor expressed on myeloid cells 1 3.16825
IER3 immediate early response 3 3.1373
MRPS22 mitochondrial ribosomal protein S22 3.12915
NRDC nardilysin convertase 3.1155
TUBB6 tubulin, beta 6 class V 3.09785
BAG2 BCL2-associated athanogene 2 3.05185
BLCAP bladder cancer associated protein 3.0321
NIT2 nitrilase family, member 2 3.0265
GYG1 glycogenin 1 2.97155
DHRS7 dehydrogenase/reductase (SDR family) member 7 2.9663
KEAP1 kelch-like ECH-associated protein 1 2.95765
MFSD1 major facilitator superfamily domain containing 1 2.94615
HARS1 histidyl-tRNA synthetase 1 2.94525
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 2.91015
TRIB3 tribbles pseudokinase 3 2.9089
RTCA RNA 3'-terminal phosphate cyclase 2.90465
TM4SF1 transmembrane 4 L six family member 1 2.90176
PPARG peroxisome proliferator-activated receptor gamma 2.90105
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae) 2.8994
ALG3 ALG3, alpha-1,3- mannosyltransferase 2.89515
NQO2 NAD(P)H dehydrogenase, quinone 2 2.8714
JUN jun proto-oncogene 2.85812
TSLIG3A tRNA splicing ligase complex subunit 3A 2.8358
FASTKD5 FAST kinase domains 5 2.8322
RALB v-ral simian leukemia viral oncogene homolog B 2.81352
ACTR8 ARP8 actin-related protein 8 homolog (yeast) 2.8115
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 2.79435
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 2.78875
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 2.78395
NANOS3 nanos homolog 3 (Drosophila) 2.77895
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 2.7461
RUVBL1 RuvB-like AAA ATPase 1 2.74245
TALDO1 transaldolase 1 2.73945
EGR1 early growth response 1 2.7385
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 2.7364
RAB5IF RAB5 interacting factor 2.7092
LRP10 low density lipoprotein receptor-related protein 10 2.70435
HKDC1 hexokinase domain containing 1 2.69445
IFRD1 interferon-related developmental regulator 1 2.69443
ZNF274 zinc finger protein 274 2.68625
MON1B MON1 secretory trafficking family member B 2.6752
UIMC1 ubiquitin interaction motif containing 1 2.6732
ADGRF5 adhesion G protein-coupled receptor F5 2.664
NQO1 NAD(P)H dehydrogenase, quinone 1 2.66002
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 2.64355
ALAS1 5'-aminolevulinate synthase 1 2.6363
GRB10 growth factor receptor-bound protein 10 2.63543
CAVIN1 caveolae associated protein 1 2.63427
MKKS McKusick-Kaufman syndrome 2.63355
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 2.633
TOMM34 translocase of outer mitochondrial membrane 34 2.62215
RPP40 ribonuclease P/MRP 40kDa subunit 2.6078
HEBP1 heme binding protein 1 2.60685
ZKSCAN2 zinc finger with KRAB and SCAN domains 2 2.6034
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 2.60165
PFN2 profilin 2 2.59655
PCDHB16 protocadherin beta 16 2.58698
INPP1 inositol polyphosphate-1-phosphatase 2.58505
STX1A syntaxin 1A (brain) 2.58475
FABP4 fatty acid binding protein 4, adipocyte 2.5667
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 2.56025
IL4R interleukin 4 receptor 2.55345
MYC v-myc avian myelocytomatosis viral oncogene homolog 2.55185
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 2.54985
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein 2.5483
ADM adrenomedullin 2.53625
WWC3 WWC family member 3 2.53455
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) 2.5289
NSFL1C NSFL1 (p97) cofactor (p47) 2.5279
KDM3A lysine (K)-specific demethylase 3A 2.52605
SPRR1B small proline-rich protein 1B 2.52205
CIDEC cell death-inducing DFFA-like effector c 2.51185
PTPN20 protein tyrosine phosphatase, non-receptor type 20 2.50895
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 2.5083
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 2.5047
CHIC2 cysteine-rich hydrophobic domain 2 2.5012
NSUN3 NOP2/Sun domain family, member 3 2.4963
DCTD dCMP deaminase 2.49588
DIABLO diablo, IAP-binding mitochondrial protein 2.49565
TXNDC15 thioredoxin domain containing 15 2.48915
G0S2 G0/G1 switch 2 2.48295
FTSJ3 FtsJ homolog 3 (E. coli) 2.47735
TRIM16 tripartite motif containing 16 2.45495
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 2.4489
VCP valosin containing protein 2.43932
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 2.42615
VWF von Willebrand factor 2.42505
SPRR3 small proline-rich protein 3 2.4039
CDCP1 CUB domain containing protein 1 2.39905
SLC35F2 solute carrier family 35, member F2 2.3881
LHFPL2 lipoma HMGIC fusion partner-like 2 2.38725
UGDH UDP-glucose 6-dehydrogenase 2.38125
F2RL1 coagulation factor II (thrombin) receptor-like 1 2.38095
SPANXB1 SPANX family, member B1 2.377
HPSE heparanase 2.359
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.3579
WDR77 WD repeat domain 77 2.35665
TRAPPC12 trafficking protein particle complex 12 2.3557
WASHC3 WASH complex subunit 3 2.3459
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 2.3452
TFG TRK-fused gene 2.34385
LOX lysyl oxidase 2.3433
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 2.3234
BLVRA biliverdin reductase A 2.31488
NAP1L2 nucleosome assembly protein 1-like 2 2.3091
COPS8 COP9 signalosome subunit 8 2.3067
PIR pirin (iron-binding nuclear protein) 2.3001
ISCA1 iron-sulfur cluster assembly 1 2.29968
NECAP1 NECAP endocytosis associated 1 2.29415
WDR25 WD repeat domain 25 2.29405
SPRR1A small proline-rich protein 1A 2.28552
DUSP6 dual specificity phosphatase 6 2.28258
GSR glutathione reductase 2.28245
MBD1 methyl-CpG binding domain protein 1 2.2792
WIPI1 WD repeat domain, phosphoinositide interacting 1 2.27623
CCNJL cyclin J-like 2.27545
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2.275
ZW10 zw10 kinetochore protein 2.2736
MERTK MER proto-oncogene, tyrosine kinase 2.26787
DGUOK deoxyguanosine kinase 2.26485
NOP16 NOP16 nucleolar protein 2.26318
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 2.26285
DYSF dysferlin 2.25975
YPEL5 yippee-like 5 (Drosophila) 2.2527
POPDC3 popeye domain containing 3 2.25075
AKR1C1 aldo-keto reductase family 1, member C1 2.24378
SNW1 SNW domain containing 1 2.24285
CETP cholesteryl ester transfer protein, plasma 2.24085
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 2.23805
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 2.2345
TLR2 toll-like receptor 2 2.2342
DDRGK1 DDRGK domain containing 1 2.2312
LSG1 large 60S subunit nuclear export GTPase 1 2.2201
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1 2.21807
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 2.21485
SECISBP2 SECIS binding protein 2 2.21235
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11 2.21135
ECPAS Ecm29 proteasome adaptor and scaffold 2.20975
GBE1 glucan (1,4-alpha-), branching enzyme 1 2.20965
PCDHB11 protocadherin beta 11 2.20381
IQCB1 IQ motif containing B1 2.2019
RIPPLY2-CYB5R4 RIPPLY2-CYB5R4 readthrough 2.2006
TLCD3A TLC domain containing 3A 2.1993
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing 2.19305
GIN1 gypsy retrotransposon integrase 1 2.19015
SRPRB signal recognition particle receptor, B subunit 2.18625
TACC2 transforming, acidic coiled-coil containing protein 2 2.18582
FKBP1A FK506 binding protein 1A, 12kDa 2.18232
MED8 mediator complex subunit 8 2.18153
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 2.17945
THBD thrombomodulin 2.16657
HAVCR1 hepatitis A virus cellular receptor 1 2.1631
EMC3 ER membrane protein complex subunit 3 2.16065
SLC38A6 solute carrier family 38, member 6 2.1588
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase 2.15755
PARL presenilin associated, rhomboid-like 2.1567
RAP1GAP RAP1 GTPase activating protein 2.1565
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 2.15595
MCFD2 multiple coagulation factor deficiency 2 2.14505
PRDM4 PR domain containing 4 2.14353
WSB2 WD repeat and SOCS box containing 2 2.1428
TJP1 tight junction protein 1 2.14167
XPA xeroderma pigmentosum, complementation group A 2.13825
ECD ecdysoneless homolog (Drosophila) 2.1233
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 2.12295
PCYT1A phosphate cytidylyltransferase 1, choline, alpha 2.1224
TERF2IP telomeric repeat binding factor 2, interacting protein 2.12065
AIM2 absent in melanoma 2 2.1166
IL36G interleukin 36, gamma 2.1158
UBAP1 ubiquitin associated protein 1 2.11565
HLX H2.0-like homeobox 2.11525
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 2.11087
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 2.1065
PUM3 pumilio RNA binding family member 3 2.1028
GLRX glutaredoxin (thioltransferase) 2.10133
CSNK1G3 casein kinase 1, gamma 3 2.1002
DPY19L1 dpy-19-like 1 (C. elegans) 2.09955
DUS2 dihydrouridine synthase 2 2.098
TSKU tsukushi, small leucine rich proteoglycan 2.09715
HSPA12A heat shock 70kDa protein 12A 2.09615
EBNA1BP2 EBNA1 binding protein 2 2.09465
BABAM2 BRISC and BRCA1 A complex member 2 2.09462
S100A3 S100 calcium binding protein A3 2.0943
RNF13 ring finger protein 13 2.09205
FKBP1C FK506 binding protein 1C 2.08
GADD45G growth arrest and DNA-damage-inducible, gamma 2.07995
AARSD1 alanyl-tRNA synthetase domain containing 1 2.07975
MAP1B microtubule-associated protein 1B 2.07597
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 2.07382
ALKBH1 alkB, alkylation repair homolog 1 (E. coli) 2.0721
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 2.0656
PWP2 PWP2 periodic tryptophan protein homolog (yeast) 2.06225
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated 2.0608
KIFBP kinesin family binding protein 2.06055
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 2.05815
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 2.05228
NAMPT nicotinamide phosphoribosyltransferase 2.04953
AMPD2 adenosine monophosphate deaminase 2 2.0487
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13 2.0475
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 2.0401
TUT7 terminal uridylyl transferase 7 2.03755
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 2.037
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 2.03632
MEAK7 MTOR associated protein, eak-7 homolog 2.03443
WDCP WD repeat and coiled coil containing 2.0295
TRIM32 tripartite motif containing 32 2.02625
PIGH phosphatidylinositol glycan anchor biosynthesis, class H 2.02575
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 2.02413
PTPRM protein tyrosine phosphatase, receptor type, M 2.02225
S100A12 S100 calcium binding protein A12 2.0213
OSMR oncostatin M receptor 2.02095
ETFB electron-transfer-flavoprotein, beta polypeptide 2.0204
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.01785
SRRD SRR1 domain containing 2.0177
FOXO1 forkhead box O1 2.01417
COQ10B coenzyme Q10 homolog B (S. cerevisiae) 2.0076
C5AR1 complement component 5a receptor 1 2.00465
WDR3 WD repeat domain 3 2.0044
PRMT5 protein arginine methyltransferase 5 2.00435

decreased expression

Symbol Name Standardized Value
APOH apolipoprotein H (beta-2-glycoprotein I) -7.7679
CXADR coxsackie virus and adenovirus receptor -7.1432
TM9SF3 transmembrane 9 superfamily member 3 -6.5702
IL17RB interleukin 17 receptor B -5.90045
TF transferrin -5.69903
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -5.4009
FBF1 Fas (TNFRSF6) binding factor 1 -5.3294
C5 complement component 5 -5.31915
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -5.0569
STMN1 stathmin 1 -4.8621
KIF4A kinesin family member 4A -4.4773
CENPE centromere protein E, 312kDa -4.26015
COG7 component of oligomeric golgi complex 7 -4.16035
HMGA2 high mobility group AT-hook 2 -4.1214
CCNB2 cyclin B2 -4.02845
KIF11 kinesin family member 11 -4.01615
TOP2A topoisomerase (DNA) II alpha 170kDa -3.9347
NCAPD2 non-SMC condensin I complex, subunit D2 -3.90645
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -3.859
APOA2 apolipoprotein A-II -3.85168
CCNA2 cyclin A2 -3.84695
KIF20A kinesin family member 20A -3.8422
NUSAP1 nucleolar and spindle associated protein 1 -3.80183
AURKB aurora kinase B -3.76635
CCNB1 cyclin B1 -3.74045
PCNA proliferating cell nuclear antigen -3.5738
FOXM1 forkhead box M1 -3.52465
VAV3 vav 3 guanine nucleotide exchange factor -3.51423
BIRC5 baculoviral IAP repeat containing 5 -3.49772
KLHDC2 kelch domain containing 2 -3.495
NDC80 NDC80 kinetochore complex component -3.48425
HNMT histamine N-methyltransferase -3.475
ASF1B anti-silencing function 1B histone chaperone -3.4363
LUM lumican -3.4346
AXIN1 axin 1 -3.43195
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -3.40615
KIF15 kinesin family member 15 -3.3867
TTC38 tetratricopeptide repeat domain 38 -3.3492
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.33667
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 -3.32625
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -3.3082
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -3.3013
S100A1 S100 calcium binding protein A1 -3.28305
CDCA8 cell division cycle associated 8 -3.2826
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -3.2567
PBLD phenazine biosynthesis-like protein domain containing -3.23395
KIFC1 kinesin family member C1 -3.21875
IFITM3 interferon induced transmembrane protein 3 -3.21615
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 -3.20335
HAT1 histone acetyltransferase 1 -3.17975
PACS2 phosphofurin acidic cluster sorting protein 2 -3.17322
GJB1 gap junction protein, beta 1, 32kDa -3.133
NAGA N-acetylgalactosaminidase, alpha- -3.10658
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -3.10485
CKAP5 cytoskeleton associated protein 5 -3.10145
BCL7C B-cell CLL/lymphoma 7C -3.08355
TPX2 TPX2, microtubule-associated -3.07975
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -3.065
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -3.0639
ASGR1 asialoglycoprotein receptor 1 -3.04395
CLMN calmin (calponin-like, transmembrane) -3.04087
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -3.0373
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -3.0094
IGFBP7 insulin-like growth factor binding protein 7 -3.006
PSRC1 proline/serine-rich coiled-coil 1 -3.00475
CARHSP1 calcium regulated heat stable protein 1, 24kDa -2.99145
FN3KRP fructosamine 3 kinase related protein -2.95465
KL klotho -2.95195
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.94475
TMEM176B transmembrane protein 176B -2.93385
H2AX H2A.X variant histone -2.9331
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -2.92405
RNF130 ring finger protein 130 -2.9228
PYGL phosphorylase, glycogen, liver -2.9213
CTNND2 catenin (cadherin-associated protein), delta 2 -2.9152
CPB2 carboxypeptidase B2 (plasma) -2.9077
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 -2.90065
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 -2.8823
PRC1 protein regulator of cytokinesis 1 -2.8578
MXD3 MAX dimerization protein 3 -2.8496
CENPA centromere protein A -2.84858
B4GAT1 beta-1,4-glucuronyltransferase 1 -2.8462
CDK1 cyclin-dependent kinase 1 -2.84525
APOC2 apolipoprotein C-II -2.8398
SYNE2 spectrin repeat containing, nuclear envelope 2 -2.8211
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -2.81973
H2AZ2 H2A.Z variant histone 2 -2.8182
MPST mercaptopyruvate sulfurtransferase -2.8148
ANG angiogenin, ribonuclease, RNase A family, 5 -2.80455
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -2.7938
FGL1 fibrinogen-like 1 -2.78575
RBMX RNA binding motif protein, X-linked -2.7727
H2AC25 H2A clustered histone 25 -2.7657
ASGR2 asialoglycoprotein receptor 2 -2.75935
LLGL2 lethal giant larvae homolog 2 (Drosophila) -2.74935
PECR peroxisomal trans-2-enoyl-CoA reductase -2.7358
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -2.73458
MCM3 minichromosome maintenance complex component 3 -2.7258
PLP1 proteolipid protein 1 -2.7217
SLC17A4 solute carrier family 17, member 4 -2.71745
OIP5 Opa interacting protein 5 -2.7165
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 -2.7147
COL1A2 collagen, type I, alpha 2 -2.71112
MKI67 marker of proliferation Ki-67 -2.7111
IFITM1 interferon induced transmembrane protein 1 -2.71002
HMGB2 high mobility group box 2 -2.7047
SIRT1 sirtuin 1 -2.69905
PDK2 pyruvate dehydrogenase kinase, isozyme 2 -2.69285
HMGN2 high mobility group nucleosomal binding domain 2 -2.68715
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase -2.68365
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) -2.6753
ALAD aminolevulinate dehydratase -2.6707
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.66325
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 -2.66
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.65928
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 -2.654
GPAA1 glycosylphosphatidylinositol anchor attachment 1 -2.6536
RASSF4 Ras association (RalGDS/AF-6) domain family member 4 -2.6532
FEN1 flap structure-specific endonuclease 1 -2.64922
HADH hydroxyacyl-CoA dehydrogenase -2.62922
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 -2.6268
MNS1 meiosis-specific nuclear structural 1 -2.6242
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 -2.6236
HELLS helicase, lymphoid-specific -2.61735
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -2.6161
MCM5 minichromosome maintenance complex component 5 -2.61208
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -2.60477
TMEM97 transmembrane protein 97 -2.59861
SOSTDC1 sclerostin domain containing 1 -2.58725
IL7 interleukin 7 -2.5827
RNF186 ring finger protein 186 -2.57975
RACGAP1 Rac GTPase activating protein 1 -2.57555
PADI2 peptidyl arginine deiminase, type II -2.57385
KIF18B kinesin family member 18B -2.5723
E2F1 E2F transcription factor 1 -2.571
A2M alpha-2-macroglobulin -2.5698
HPX hemopexin -2.5685
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 -2.55475
HMMR hyaluronan-mediated motility receptor (RHAMM) -2.55338
CHAF1A chromatin assembly factor 1, subunit A (p150) -2.54958
BRCA1 breast cancer 1, early onset -2.54935
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -2.5305
RBM41 RNA binding motif protein 41 -2.52985
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C -2.52822
CDO1 cysteine dioxygenase type 1 -2.52775
ATAD2 ATPase family, AAA domain containing 2 -2.52345
PAH phenylalanine hydroxylase -2.51713
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived) -2.5132
TRIP13 thyroid hormone receptor interactor 13 -2.5037
NUP85 nucleoporin 85kDa -2.49055
CDC20 cell division cycle 20 -2.4846
MSH2 mutS homolog 2 -2.4809
FRAT1 frequently rearranged in advanced T-cell lymphomas 1 -2.4774
KIF22 kinesin family member 22 -2.46352
SPC25 SPC25, NDC80 kinetochore complex component -2.4575
GTSE1 G-2 and S-phase expressed 1 -2.45679
RNASE4 ribonuclease, RNase A family, 4 -2.45368
BIRC3 baculoviral IAP repeat containing 3 -2.45315
ZDHHC4 zinc finger, DHHC-type containing 4 -2.45015
MCM7 minichromosome maintenance complex component 7 -2.43898
PAQR4 progestin and adipoQ receptor family member IV -2.42795
GPRC5B G protein-coupled receptor, class C, group 5, member B -2.42768
ADH6 alcohol dehydrogenase 6 (class V) -2.42747
PBK PDZ binding kinase -2.4263
CDC25C cell division cycle 25C -2.42587
ACSM2A acyl-CoA synthetase medium-chain family member 2A -2.41815
PLG plasminogen -2.41603
AUNIP aurora kinase A and ninein interacting protein -2.41435
CDKN2AIP CDKN2A interacting protein -2.40805
PCYT2 phosphate cytidylyltransferase 2, ethanolamine -2.39585
E2F8 E2F transcription factor 8 -2.3921
ZMYM3 zinc finger, MYM-type 3 -2.38805
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 -2.38555
TMEM176A transmembrane protein 176A -2.37555
TROAP trophinin associated protein -2.3716
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.3716
PLEKHA5 pleckstrin homology domain containing, family A member 5 -2.36905
CAPN9 calpain 9 -2.3682
KLK1 kallikrein 1 -2.36795
CFHR2 complement factor H-related 2 -2.3644
PGM1 phosphoglucomutase 1 -2.36415
NOX1 NADPH oxidase 1 -2.3617
NCAPH non-SMC condensin I complex, subunit H -2.35825
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 -2.35715
G6PC1 glucose-6-phosphatase catalytic subunit 1 -2.3545
TTK TTK protein kinase -2.3515
FTCD formimidoyltransferase cyclodeaminase -2.3475
CDK2 cyclin-dependent kinase 2 -2.34728
PLK4 polo-like kinase 4 -2.34248
TM4SF5 transmembrane 4 L six family member 5 -2.3329
AMOT angiomotin -2.3269
PTTG1 pituitary tumor-transforming 1 -2.32445
TNS3 tensin 3 -2.3218
PCCA propionyl CoA carboxylase, alpha polypeptide -2.32155
FABP1 fatty acid binding protein 1, liver -2.3201
NEK2 NIMA-related kinase 2 -2.3139
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.31238
KNG1 kininogen 1 -2.3115
GRID1 glutamate receptor, ionotropic, delta 1 -2.30742
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 -2.3066
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.30555
COL3A1 collagen, type III, alpha 1 -2.29672
RNF125 ring finger protein 125, E3 ubiquitin protein ligase -2.29545
WNT4 wingless-type MMTV integration site family, member 4 -2.29245
SLC44A1 solute carrier family 44 (choline transporter), member 1 -2.28865
SCARA3 scavenger receptor class A, member 3 -2.28385
PIPOX pipecolic acid oxidase -2.2826
RRM1 ribonucleotide reductase M1 -2.28258
MREG melanoregulin -2.2816
LBR lamin B receptor -2.2766
TJP3 tight junction protein 3 -2.27638
FGA fibrinogen alpha chain -2.27565
RPUSD2 RNA pseudouridylate synthase domain containing 2 -2.26505
IFITM2 interferon induced transmembrane protein 2 -2.2642
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) -2.25798
PLXNB2 plexin B2 -2.25575
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 -2.25305
PLK1 polo-like kinase 1 -2.247
REPIN1 replication initiator 1 -2.24345
ERI2 ERI1 exoribonuclease family member 2 -2.24295
NLRP4 NLR family, pyrin domain containing 4 -2.23805
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase -2.23635
USP11 ubiquitin specific peptidase 11 -2.2271
CLASRP CLK4-associating serine/arginine rich protein -2.22585
PROS1 protein S (alpha) -2.22455
MED24 mediator complex subunit 24 -2.2221
CDCA4 cell division cycle associated 4 -2.2219
RAB4A RAB4A, member RAS oncogene family -2.21863
CADM1 cell adhesion molecule 1 -2.21433
ASPA aspartoacylase -2.21345
COL9A3 collagen, type IX, alpha 3 -2.2122
FAIM Fas apoptotic inhibitory molecule -2.20635
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -2.2059
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain -2.20155
TBC1D31 TBC1 domain family, member 31 -2.20145
LRRC31 leucine rich repeat containing 31 -2.1997
POLM polymerase (DNA directed), mu -2.1993
AMBP alpha-1-microglobulin/bikunin precursor -2.199
NRTN neurturin -2.199
SLC30A10 solute carrier family 30, member 10 -2.19765
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 -2.19605
DBNDD2 dysbindin (dystrobrevin binding protein 1) domain containing 2 -2.19355
TM7SF2 transmembrane 7 superfamily member 2 -2.19235
ITGA7 integrin, alpha 7 -2.19185
WFDC1 WAP four-disulfide core domain 1 -2.18885
CDC45 cell division cycle 45 -2.18795
CHKA choline kinase alpha -2.1831
GCDH glutaryl-CoA dehydrogenase -2.18202
TK1 thymidine kinase 1, soluble -2.1787
BPHL biphenyl hydrolase-like (serine hydrolase) -2.1785
CFHR3 complement factor H-related 3 -2.1783
SREBF2 sterol regulatory element binding transcription factor 2 -2.17723
IP6K1 inositol hexakisphosphate kinase 1 -2.1772
ERN2 endoplasmic reticulum to nucleus signaling 2 -2.17595
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -2.16785
DNM2 dynamin 2 -2.16585
MATK megakaryocyte-associated tyrosine kinase -2.16255
LMNB1 lamin B1 -2.1597
APLP1 amyloid beta (A4) precursor-like protein 1 -2.15935
PPT2 palmitoyl-protein thioesterase 2 -2.1562
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 -2.15265
S100B S100 calcium binding protein B -2.15025
CEP57 centrosomal protein 57kDa -2.1458
MEST mesoderm specific transcript -2.1442
ISYNA1 inositol-3-phosphate synthase 1 -2.1398
PCNT pericentrin -2.13845
TMSB15B thymosin beta 15B -2.1316
FANCA Fanconi anemia, complementation group A -2.13118
RNF208 ring finger protein 208 -2.1295
DCT dopachrome tautomerase -2.12559
GLUL glutamate-ammonia ligase -2.12238
LSR lipolysis stimulated lipoprotein receptor -2.1218
HGH1 HGH1 homolog (S. cerevisiae) -2.1164
FAM107A family with sequence similarity 107, member A -2.11597
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) -2.11445
FANCG Fanconi anemia, complementation group G -2.11175
CDCA3 cell division cycle associated 3 -2.11015
ACSM3 acyl-CoA synthetase medium-chain family member 3 -2.10737
UBE2C ubiquitin-conjugating enzyme E2C -2.10725
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -2.10722
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) -2.103
SOX9 SRY (sex determining region Y)-box 9 -2.10258
IBSP integrin-binding sialoprotein -2.10175
PGPEP1 pyroglutamyl-peptidase I -2.10125
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -2.1007
PYCARD PYD and CARD domain containing -2.09705
NCAPG2 non-SMC condensin II complex, subunit G2 -2.0967
TRMT5 tRNA methyltransferase 5 -2.0949
SDC2 syndecan 2 -2.09235
FRAT2 frequently rearranged in advanced T-cell lymphomas 2 -2.0919
LGALS4 lectin, galactoside-binding, soluble, 4 -2.09075
PIMREG PICALM interacting mitotic regulator -2.0902
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) -2.0886
KIF1B kinesin family member 1B -2.08745
PTGDS prostaglandin D2 synthase 21kDa (brain) -2.0858
APOM apolipoprotein M -2.08558
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.08555
ERBB2 erb-b2 receptor tyrosine kinase 2 -2.08148
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide -2.08025
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide -2.0795
MSH5 mutS homolog 5 -2.07725
SQLE squalene epoxidase -2.07098
CLASP2 cytoplasmic linker associated protein 2 -2.06977
CYB5R3 cytochrome b5 reductase 3 -2.06695
A1CF APOBEC1 complementation factor -2.06555
CCNE1 cyclin E1 -2.06545
SEPHS1 selenophosphate synthetase 1 -2.06353
GLCE glucuronic acid epimerase -2.06315
EHMT2 euchromatic histone-lysine N-methyltransferase 2 -2.0625
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 -2.05713
SHTN1 shootin 1 -2.0554
ALDOB aldolase B, fructose-bisphosphate -2.05464
VRK1 vaccinia related kinase 1 -2.05445
CLPS colipase, pancreatic -2.05425
PRODH2 proline dehydrogenase (oxidase) 2 -2.05415
PTEN phosphatase and tensin homolog -2.05229
NAE1 NEDD8 activating enzyme E1 subunit 1 -2.0499
ELSPBP1 epididymal sperm binding protein 1 -2.0497
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2 -2.049
ARSA arylsulfatase A -2.0461
FANCI Fanconi anemia, complementation group I -2.04515
IQCE IQ motif containing E -2.04507
NXPE4 neurexophilin and PC-esterase domain family, member 4 -2.04485
THOP1 thimet oligopeptidase 1 -2.0442
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 -2.04295
ALS2CL ALS2 C-terminal like -2.04295
SESN1 sestrin 1 -2.04025
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -2.0384
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 -2.03545
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 -2.03465
SH2B2 SH2B adaptor protein 2 -2.03215
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 -2.0302
CES3 carboxylesterase 3 -2.03015
ZNF652 zinc finger protein 652 -2.02815
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -2.02645
C8A complement component 8, alpha polypeptide -2.02595
GPR19 G protein-coupled receptor 19 -2.0224
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -2.02205
USP1 ubiquitin specific peptidase 1 -2.02168
TNFSF12-TNFSF13 TNFSF12-TNFSF13 readthrough -2.02033
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 -2.0197
C8B complement component 8, beta polypeptide -2.01965
PXMP4 peroxisomal membrane protein 4, 24kDa -2.018
ERCC6L excision repair cross-complementation group 6-like -2.01795
OTULINL OTU deubiquitinase with linear linkage specificity like -2.01312
LMF2 lipase maturation factor 2 -2.01297
SORT1 sortilin 1 -2.00947
DHFR dihydrofolate reductase -2.00892
PPP4C protein phosphatase 4, catalytic subunit -2.0068
DUSP10 dual specificity phosphatase 10 -2.00662
SPAG5 sperm associated antigen 5 -2.005
PLXNB1 plexin B1 -2.00445
CYP3A7-CYP3A51P CYP3A7-CYP3A51P readthrough -2.0031
FCHSD2 FCH and double SH3 domains 2 -2.0025