CRCGN015_HEPG2_48H:B18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description beta-naphthoflavone 11.11 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

513 genes differentially expressed following the CRCGN015_HEPG2_48H:B18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HMOX1 heme oxygenase 1 8.90065
ABHD4 abhydrolase domain containing 4 7.0453
CTSL cathepsin L 6.24135
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 5.57845
TXNRD1 thioredoxin reductase 1 5.28225
HOXA10 homeobox A10 5.00385
SNX11 sorting nexin 11 4.86013
NUCB2 nucleobindin 2 4.58995
MAPK13 mitogen-activated protein kinase 13 4.34552
GCLM glutamate-cysteine ligase, modifier subunit 4.3195
PHKA1 phosphorylase kinase, alpha 1 (muscle) 4.2544
SQSTM1 sequestosome 1 4.15728
KIF5C kinesin family member 5C 4.1267
REXO2 RNA exonuclease 2 4.07611
KEAP1 kelch-like ECH-associated protein 1 4.0322
PLSCR3 phospholipid scramblase 3 3.96315
TRIB1 tribbles pseudokinase 1 3.9354
FHL2 four and a half LIM domains 2 3.86525
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 3.82815
FOSL1 FOS-like antigen 1 3.6406
EGR1 early growth response 1 3.47108
GADD45B growth arrest and DNA-damage-inducible, beta 3.42368
BLCAP bladder cancer associated protein 3.3914
TRIB3 tribbles pseudokinase 3 3.37895
ALAS1 5'-aminolevulinate synthase 1 3.31815
VAT1 vesicle amine transport 1 3.3163
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 3.27985
ZFP36 ZFP36 ring finger protein 3.27875
EVL Enah/Vasp-like 3.27125
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 3.25795
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.24275
PCDHB16 protocadherin beta 16 3.22878
IER3 immediate early response 3 3.21585
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 3.15845
EIF6 eukaryotic translation initiation factor 6 3.12175
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 3.0182
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 3.00895
TUBB6 tubulin, beta 6 class V 3.0073
CCND3 cyclin D3 2.9481
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 2.91965
NAV3 neuron navigator 3 2.91175
TALDO1 transaldolase 1 2.90755
JUN jun proto-oncogene 2.885
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 2.868
NQO1 NAD(P)H dehydrogenase, quinone 1 2.84518
UNKL unkempt family zinc finger-like 2.83845
AMPD2 adenosine monophosphate deaminase 2 2.8025
RHOF ras homolog family member F (in filopodia) 2.7402
EMC3 ER membrane protein complex subunit 3 2.7372
UTP11 UTP11 small subunit processome component 2.7233
PRDX1 peroxiredoxin 1 2.71275
LRP10 low density lipoprotein receptor-related protein 10 2.6983
PHC2 polyhomeotic homolog 2 (Drosophila) 2.6919
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 2.67355
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 2.66285
NANOS3 nanos homolog 3 (Drosophila) 2.6574
ALDOC aldolase C, fructose-bisphosphate 2.63135
TSLIG3A tRNA splicing ligase complex subunit 3A 2.62355
GRB10 growth factor receptor-bound protein 10 2.62003
GBE1 glucan (1,4-alpha-), branching enzyme 1 2.619
PIR pirin (iron-binding nuclear protein) 2.61635
IL4R interleukin 4 receptor 2.61465
SLC35F2 solute carrier family 35, member F2 2.6122
UGDH UDP-glucose 6-dehydrogenase 2.58715
SRPX sushi-repeat containing protein, X-linked 2.5723
CEMIP2 cell migration inducing hyaluronidase 2 2.5714
TOMM34 translocase of outer mitochondrial membrane 34 2.54795
TRIM16 tripartite motif containing 16 2.5386
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 2.53785
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 2.51545
MANF mesencephalic astrocyte-derived neurotrophic factor 2.50205
DCTD dCMP deaminase 2.49793
TTI1 TELO2 interacting protein 1 2.4963
PFN2 profilin 2 2.4866
PROCR protein C receptor, endothelial 2.46465
CTSG cathepsin G 2.45955
HOXA10-HOXA9 HOXA10-HOXA9 readthrough 2.44515
FASTKD5 FAST kinase domains 5 2.4371
AATF apoptosis antagonizing transcription factor 2.43615
CBR1 carbonyl reductase 1 2.4305
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11 2.42375
DHRS7 dehydrogenase/reductase (SDR family) member 7 2.4224
HOXA11 homeobox A11 2.41775
NAP1L2 nucleosome assembly protein 1-like 2 2.40905
S100A11 S100 calcium binding protein A11 2.4076
TMEM208 transmembrane protein 208 2.40575
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 2.4053
CDA cytidine deaminase 2.3917
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 2.391
STX1A syntaxin 1A (brain) 2.38925
ELOVL1 ELOVL fatty acid elongase 1 2.38162
VWF von Willebrand factor 2.377
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 2.3736
MAP2K5 mitogen-activated protein kinase kinase 5 2.37033
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 2.36865
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 2.3592
CES1 carboxylesterase 1 2.35915
PELO pelota homolog (Drosophila) 2.35095
YY1AP1 YY1 associated protein 1 2.3373
GOLM1 golgi membrane protein 1 2.32585
TTC4 tetratricopeptide repeat domain 4 2.3171
MYC v-myc avian myelocytomatosis viral oncogene homolog 2.30495
RAB5IF RAB5 interacting factor 2.30025
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 2.2805
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 2.274
BLVRB biliverdin reductase B 2.27
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 2.26055
NOP16 NOP16 nucleolar protein 2.25938
SQOR sulfide quinone oxidoreductase 2.2449
LOC128966597 MAL-like protein 2.24415
BATF basic leucine zipper transcription factor, ATF-like 2.2319
CCR7 chemokine (C-C motif) receptor 7 2.2295
UBL4A ubiquitin-like 4A 2.22865
CAVIN1 caveolae associated protein 1 2.21568
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 2.20485
ALG3 ALG3, alpha-1,3- mannosyltransferase 2.19925
PARL presenilin associated, rhomboid-like 2.1924
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 2.18705
CDK5RAP2 CDK5 regulatory subunit associated protein 2 2.18145
AZU1 azurocidin 1 2.17755
AKR1C1 aldo-keto reductase family 1, member C1 2.17702
KIZ kizuna centrosomal protein 2.1741
GRAMD1B GRAM domain containing 1B 2.1669
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 2.16125
VSIG4 V-set and immunoglobulin domain containing 4 2.16025
PPIB peptidylprolyl isomerase B (cyclophilin B) 2.15747
EXOC1 exocyst complex component 1 2.15565
TM4SF1 transmembrane 4 L six family member 1 2.155
RAP1GAP RAP1 GTPase activating protein 2.1512
BLTP3B bridge-like lipid transfer protein family member 3B 2.1501
TRIP4 thyroid hormone receptor interactor 4 2.1378
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 2.12908
AKR1C3 aldo-keto reductase family 1, member C3 2.12745
CD163 CD163 molecule 2.12738
EMC7 ER membrane protein complex subunit 7 2.1105
BAG2 BCL2-associated athanogene 2 2.104
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 2.1032
EIPR1 EARP complex and GARP complex interacting protein 1 2.09785
AARSD1 alanyl-tRNA synthetase domain containing 1 2.09305
LAMA2 laminin, alpha 2 2.09135
ARHGAP12 Rho GTPase activating protein 12 2.08565
YARS1 tyrosyl-tRNA synthetase 1 2.07255
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa 2.07055
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 2.06218
EBNA1BP2 EBNA1 binding protein 2 2.0616
FOXD1 forkhead box D1 2.0603
RPH3AL rabphilin 3A-like (without C2 domains) 2.05985
RAI1 retinoic acid induced 1 2.0587
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.05325
TMED3 transmembrane emp24 protein transport domain containing 3 2.0475
DPY19L1 dpy-19-like 1 (C. elegans) 2.04495
MYDGF myeloid-derived growth factor 2.0441
TXNL1 thioredoxin-like 1 2.0353
ZNF274 zinc finger protein 274 2.0211
MNT MAX network transcriptional repressor 2.01835
IER2 immediate early response 2 2.01615
PRTN3 proteinase 3 2.01205
ADM adrenomedullin 2.00805
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.00745
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 2.00575
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.0052
DENR density-regulated protein 2.0016

decreased expression

Symbol Name Standardized Value
CXADR coxsackie virus and adenovirus receptor -7.63555
APOH apolipoprotein H (beta-2-glycoprotein I) -6.0399
TF transferrin -5.42901
PROM1 prominin 1 -5.3379
NCK1 NCK adaptor protein 1 -5.32527
C5 complement component 5 -5.04215
FAIM Fas apoptotic inhibitory molecule -4.99505
APOA2 apolipoprotein A-II -4.66948
IL17RB interleukin 17 receptor B -4.4051
STMN1 stathmin 1 -4.32845
FBF1 Fas (TNFRSF6) binding factor 1 -4.3239
FBXO7 F-box protein 7 -3.5878
NUSAP1 nucleolar and spindle associated protein 1 -3.47188
S100A1 S100 calcium binding protein A1 -3.41935
SLC17A2 solute carrier family 17, member 2 -3.39145
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.3588
CEP70 centrosomal protein 70kDa -3.31
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 -3.2842
COG7 component of oligomeric golgi complex 7 -3.24305
IL7 interleukin 7 -3.23685
PIMREG PICALM interacting mitotic regulator -3.2356
VAV3 vav 3 guanine nucleotide exchange factor -3.23395
HMGA2 high mobility group AT-hook 2 -3.2319
ZDHHC4 zinc finger, DHHC-type containing 4 -3.2182
AURKB aurora kinase B -3.20705
PYGL phosphorylase, glycogen, liver -3.18885
KLHDC2 kelch domain containing 2 -3.1239
LEFTY1 left-right determination factor 1 -3.10155
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -3.08765
GRIK1 glutamate receptor, ionotropic, kainate 1 -3.05632
KCNK10 potassium channel, two pore domain subfamily K, member 10 -3.0482
ASGR1 asialoglycoprotein receptor 1 -3.0363
SESN1 sestrin 1 -3.0062
SOAT2 sterol O-acyltransferase 2 -2.96362
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 -2.90217
ERN2 endoplasmic reticulum to nucleus signaling 2 -2.8938
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 -2.88555
RNLS renalase, FAD-dependent amine oxidase -2.87835
ZNF124 zinc finger protein 124 -2.87145
CXCR6 chemokine (C-X-C motif) receptor 6 -2.85645
HNMT histamine N-methyltransferase -2.83993
MREG melanoregulin -2.8204
BIRC5 baculoviral IAP repeat containing 5 -2.80588
CCHCR1 coiled-coil alpha-helical rod protein 1 -2.78099
CEP57 centrosomal protein 57kDa -2.77634
RNF130 ring finger protein 130 -2.77275
RNF125 ring finger protein 125, E3 ubiquitin protein ligase -2.7517
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -2.7492
CPB2 carboxypeptidase B2 (plasma) -2.7465
CCL20 chemokine (C-C motif) ligand 20 -2.7442
ALG12 ALG12, alpha-1,6-mannosyltransferase -2.73055
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -2.7099
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A -2.703
YBX2 Y box binding protein 2 -2.6961
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -2.6914
MYO18A myosin XVIIIA -2.68035
PGPEP1 pyroglutamyl-peptidase I -2.67915
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 -2.67275
ZMYM3 zinc finger, MYM-type 3 -2.67265
CLMN calmin (calponin-like, transmembrane) -2.66747
RBMX RNA binding motif protein, X-linked -2.6638
TMEM212 transmembrane protein 212 -2.66255
PSRC1 proline/serine-rich coiled-coil 1 -2.6598
BIRC3 baculoviral IAP repeat containing 3 -2.65785
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 -2.65695
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) -2.6544
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.6514
FKBP1B FK506 binding protein 1B, 12.6 kDa -2.64715
CER1 cerberus 1, DAN family BMP antagonist -2.64395
BEX4 brain expressed, X-linked 4 -2.64235
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -2.63565
NCAPD2 non-SMC condensin I complex, subunit D2 -2.6246
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 -2.62225
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.6122
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -2.60595
SDC2 syndecan 2 -2.60312
UBE2W ubiquitin-conjugating enzyme E2W (putative) -2.5984
CCNA2 cyclin A2 -2.59445
CCNB1 cyclin B1 -2.58825
ADGRF1 adhesion G protein-coupled receptor F1 -2.57735
PACS2 phosphofurin acidic cluster sorting protein 2 -2.57695
PGM1 phosphoglucomutase 1 -2.57505
POGLUT1 protein O-glucosyltransferase 1 -2.5729
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -2.56665
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 -2.56145
CES3 carboxylesterase 3 -2.55945
NXPE4 neurexophilin and PC-esterase domain family, member 4 -2.5519
CARHSP1 calcium regulated heat stable protein 1, 24kDa -2.54485
ASF1B anti-silencing function 1B histone chaperone -2.5401
GYG2 glycogenin 2 -2.53185
GLUL glutamate-ammonia ligase -2.53118
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -2.52995
SHOX short stature homeobox -2.52265
ELAC1 elaC ribonuclease Z 1 -2.5226
C4BPA complement component 4 binding protein, alpha -2.51605
RRAGB Ras-related GTP binding B -2.5156
MOB3B MOB kinase activator 3B -2.5118
KRT83 keratin 83, type II -2.5098
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.4977
SYNE2 spectrin repeat containing, nuclear envelope 2 -2.49615
CCDC15 coiled-coil domain containing 15 -2.49555
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 -2.49545
PECR peroxisomal trans-2-enoyl-CoA reductase -2.4796
LTB lymphotoxin beta (TNF superfamily, member 3) -2.47945
ZKSCAN3 zinc finger with KRAB and SCAN domains 3 -2.4754
INHA inhibin, alpha -2.47175
FOXH1 forkhead box H1 -2.4699
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase -2.46975
NTAN1 N-terminal asparagine amidase -2.46883
NLRP4 NLR family, pyrin domain containing 4 -2.46625
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 -2.4647
MMP15 matrix metallopeptidase 15 (membrane-inserted) -2.46395
KIF15 kinesin family member 15 -2.46155
RPA3 replication protein A3, 14kDa -2.45945
CCL16 chemokine (C-C motif) ligand 16 -2.4556
ITGB8 integrin, beta 8 -2.45233
FUZ fuzzy planar cell polarity protein -2.4482
IQCC IQ motif containing C -2.4351
TMBIM4 transmembrane BAX inhibitor motif containing 4 -2.42985
LITAF lipopolysaccharide-induced TNF factor -2.4272
TLR3 toll-like receptor 3 -2.42575
TTPA tocopherol (alpha) transfer protein -2.4248
AMOT angiomotin -2.42405
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -2.42215
SUN1 Sad1 and UNC84 domain containing 1 -2.41962
PNPLA3 patatin-like phospholipase domain containing 3 -2.4106
NEUROD6 neuronal differentiation 6 -2.40825
ADH6 alcohol dehydrogenase 6 (class V) -2.406
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 -2.4054
CCL24 chemokine (C-C motif) ligand 24 -2.4045
LPAR6 lysophosphatidic acid receptor 6 -2.4012
PLK4 polo-like kinase 4 -2.3985
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta -2.39587
HRH2 histamine receptor H2 -2.39445
NCK2 NCK adaptor protein 2 -2.39045
PLA2G3 phospholipase A2, group III -2.3892
HGFAC HGF activator -2.38675
VASH1 vasohibin 1 -2.38595
H2AZ2 H2A.Z variant histone 2 -2.38535
NOX1 NADPH oxidase 1 -2.38475
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 -2.38385
PIPOX pipecolic acid oxidase -2.383
PHACTR4 phosphatase and actin regulator 4 -2.3798
TM7SF2 transmembrane 7 superfamily member 2 -2.37855
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3 -2.3772
IFITM3 interferon induced transmembrane protein 3 -2.37595
GABRD gamma-aminobutyric acid (GABA) A receptor, delta -2.37315
CSPG4 chondroitin sulfate proteoglycan 4 -2.37315
MXD3 MAX dimerization protein 3 -2.3708
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.37055
CATSPERB catsper channel auxiliary subunit beta -2.36565
E2F8 E2F transcription factor 8 -2.3641
EPS8L2 EPS8-like 2 -2.3607
CENPA centromere protein A -2.35935
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 -2.35186
SSBP3 single stranded DNA binding protein 3 -2.3512
A1CF APOBEC1 complementation factor -2.3492
NFYB nuclear transcription factor Y, beta -2.3482
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -2.34775
HOXC11 homeobox C11 -2.34415
SLC7A10 solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 -2.3407
KANSL1L KAT8 regulatory NSL complex subunit 1-like -2.3395
MSH2 mutS homolog 2 -2.33855
RNF5 ring finger protein 5, E3 ubiquitin protein ligase -2.3375
ISYNA1 inositol-3-phosphate synthase 1 -2.3324
ONECUT1 one cut homeobox 1 -2.32955
TM7SF3 transmembrane 7 superfamily member 3 -2.3244
OIP5 Opa interacting protein 5 -2.3196
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 -2.3134
BPHL biphenyl hydrolase-like (serine hydrolase) -2.31135
TPM2 tropomyosin 2 (beta) -2.311
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 -2.30925
NKX2-2 NK2 homeobox 2 -2.30885
TOP2A topoisomerase (DNA) II alpha 170kDa -2.3068
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1 -2.3029
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase -2.3026
TMEM63A transmembrane protein 63A -2.30259
DHCR24 24-dehydrocholesterol reductase -2.2985
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 -2.29605
HADH hydroxyacyl-CoA dehydrogenase -2.29543
LRRC61 leucine rich repeat containing 61 -2.291
SOX3 SRY (sex determining region Y)-box 3 -2.28675
RYK receptor-like tyrosine kinase -2.28402
RIPPLY3 ripply transcriptional repressor 3 -2.28285
MYL9 myosin, light chain 9, regulatory -2.28275
DUSP10 dual specificity phosphatase 10 -2.28195
IFITM1 interferon induced transmembrane protein 1 -2.27875
LOC128966586 pepsin A-4-like -2.2773
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase -2.2758
AMBP alpha-1-microglobulin/bikunin precursor -2.275
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 -2.27365
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1 -2.27095
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.26995
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 -2.2697
TGIF2 TGFB-induced factor homeobox 2 -2.26345
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -2.26135
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -2.2609
MKNK1 MAP kinase interacting serine/threonine kinase 1 -2.25825
CCNB2 cyclin B2 -2.258
NEK2 NIMA-related kinase 2 -2.25297
PBLD phenazine biosynthesis-like protein domain containing -2.24355
GFRA1 GDNF family receptor alpha 1 -2.2432
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 -2.24137
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.2408
COL1A2 collagen, type I, alpha 2 -2.23905
SREBF2 sterol regulatory element binding transcription factor 2 -2.23335
TJP3 tight junction protein 3 -2.23165
ATF7IP2 activating transcription factor 7 interacting protein 2 -2.23095
RIDA reactive intermediate imine deaminase A homolog -2.22975
MACROH2A2 macroH2A.2 histone -2.22665
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.223
PAH phenylalanine hydroxylase -2.21935
ZNF33B zinc finger protein 33B -2.21875
SRD5A3 steroid 5 alpha-reductase 3 -2.21625
TTC21B tetratricopeptide repeat domain 21B -2.2121
DPF1 D4, zinc and double PHD fingers family 1 -2.21055
SKI SKI proto-oncogene -2.2039
PYCARD PYD and CARD domain containing -2.203
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 -2.19705
PROZ protein Z, vitamin K-dependent plasma glycoprotein -2.1943
ZG16 zymogen granule protein 16 -2.1924
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 -2.19075
RNF186 ring finger protein 186 -2.18585
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) -2.1841
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.1828
KIF11 kinesin family member 11 -2.18065
C8A complement component 8, alpha polypeptide -2.18045
FCHSD2 FCH and double SH3 domains 2 -2.1783
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 -2.1766
L2HGDH L-2-hydroxyglutarate dehydrogenase -2.17085
MNS1 meiosis-specific nuclear structural 1 -2.17045
ELSPBP1 epididymal sperm binding protein 1 -2.1704
ERBB3 erb-b2 receptor tyrosine kinase 3 -2.16773
TBC1D31 TBC1 domain family, member 31 -2.16445
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 -2.1639
EDIL3 EGF-like repeats and discoidin I-like domains 3 -2.15805
B4GAT1 beta-1,4-glucuronyltransferase 1 -2.156
ZNF652 zinc finger protein 652 -2.1559
CD1E CD1e molecule -2.15577
CA4 carbonic anhydrase IV -2.15438
HLA-F major histocompatibility complex, class I, F -2.1537
HMGN2 high mobility group nucleosomal binding domain 2 -2.15175
DUSP9 dual specificity phosphatase 9 -2.14975
SMIM41 small integral membrane protein 41 -2.14965
DNAH7 dynein, axonemal, heavy chain 7 -2.14895
TLR5 toll-like receptor 5 -2.1473
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) -2.14555
ANO2 anoctamin 2, calcium activated chloride channel -2.14525
TRIB2 tribbles pseudokinase 2 -2.14392
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) -2.14272
ANKRD36C ankyrin repeat domain 36C -2.13925
SOX5 SRY (sex determining region Y)-box 5 -2.13815
MIS18A MIS18 kinetochore protein A -2.13645
PRKCB protein kinase C, beta -2.13453
CLIC4 chloride intracellular channel 4 -2.13272
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta -2.13195
AHCY adenosylhomocysteinase -2.1296
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 -2.12885
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 -2.12865
AAAS achalasia, adrenocortical insufficiency, alacrimia -2.12735
NRTN neurturin -2.12675
YPEL1 yippee-like 1 (Drosophila) -2.12615
PICK1 protein interacting with PRKCA 1 -2.1246
APOL6 apolipoprotein L, 6 -2.12395
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) -2.12302
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 -2.11987
SRSF4 serine/arginine-rich splicing factor 4 -2.1188
SPATA6 spermatogenesis associated 6 -2.1186
CCKBR cholecystokinin B receptor -2.11705
PARD6A par-6 family cell polarity regulator alpha -2.11675
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 -2.1142
POLH polymerase (DNA directed), eta -2.11365
GCHFR GTP cyclohydrolase I feedback regulator -2.1132
ATP10B ATPase, class V, type 10B -2.11135
CSPP1 centrosome and spindle pole associated protein 1 -2.11125
LRRC31 leucine rich repeat containing 31 -2.1094
WNT8B wingless-type MMTV integration site family, member 8B -2.1083
CCN5 cellular communication network factor 5 -2.1061
FGL1 fibrinogen-like 1 -2.10495
ZMYM6 zinc finger, MYM-type 6 -2.1047
CD7 CD7 molecule -2.10297
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -2.10235
SULF1 sulfatase 1 -2.10227
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like -2.10165
HACL2 2-hydroxyacyl-CoA lyase 2 -2.10068
SHMT1 serine hydroxymethyltransferase 1 (soluble) -2.10055
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) -2.0979
GRAP2 GRB2-related adaptor protein 2 -2.09765
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 -2.0976
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) -2.09665
AKAP5 A kinase (PRKA) anchor protein 5 -2.0951
SELENBP1 selenium binding protein 1 -2.09425
ONECUT2 one cut homeobox 2 -2.094
MYD88 myeloid differentiation primary response 88 -2.0934
CCR6 chemokine (C-C motif) receptor 6 -2.0929
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 -2.09258
RGS7 regulator of G-protein signaling 7 -2.09105
DCC DCC netrin 1 receptor -2.0838
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 -2.0832
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 -2.083
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11 -2.081
GNG7 guanine nucleotide binding protein (G protein), gamma 7 -2.0808
PIERCE1 piercer of microtubule wall 1 -2.0803
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 -2.08015
CCDC33 coiled-coil domain containing 33 -2.07955
LAX1 lymphocyte transmembrane adaptor 1 -2.07485
HMGB2 high mobility group box 2 -2.0747
ZIC3 Zic family member 3 -2.07455
TPM1 tropomyosin 1 (alpha) -2.07324
CEP131 centrosomal protein 131kDa -2.0722
S100B S100 calcium binding protein B -2.0653
FOXM1 forkhead box M1 -2.06205
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 -2.05995
TAPBPL TAP binding protein-like -2.05903
SRP9 signal recognition particle 9kDa -2.05795
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.05635
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) -2.05551
CLEC4A C-type lectin domain family 4, member A -2.05175
FTCD formimidoyltransferase cyclodeaminase -2.05115
HOXC4 homeobox C4 -2.04835
CIRSR corepressor of RBPJ and splicing regulator -2.0481
EIF5 eukaryotic translation initiation factor 5 -2.04675
ZBTB14 zinc finger and BTB domain containing 14 -2.04563
CLDN14 claudin 14 -2.04555
PCSK1 proprotein convertase subtilisin/kexin type 1 -2.0451
HPX hemopexin -2.04418
DMAC2L distal membrane arm assembly component 2 like -2.04065
SLC17A4 solute carrier family 17, member 4 -2.03875
SCN1A sodium channel, voltage gated, type I alpha subunit -2.0384
PSIP1 PC4 and SFRS1 interacting protein 1 -2.03838
MRE11 MRE11 homolog, double strand break repair nuclease -2.03778
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) -2.0372
GAS1 growth arrest-specific 1 -2.03635
CD1B CD1b molecule -2.03605
IFNGR1 interferon gamma receptor 1 -2.03505
CHRM3 cholinergic receptor, muscarinic 3 -2.03235
CDCA4 cell division cycle associated 4 -2.0235
MKRN3 makorin ring finger protein 3 -2.02045
BTN2A2 butyrophilin, subfamily 2, member A2 -2.01737
ADTRP androgen-dependent TFPI-regulating protein -2.0166
MB myoglobin -2.01345
ZNF160 zinc finger protein 160 -2.01225
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 -2.01095
SLC35E2B solute carrier family 35, member E2B -2.01065
PGCKA1 PDCD10 and GCKIII kinases associated 1 -2.00895
RAB17 RAB17, member RAS oncogene family -2.00895
GRK3 G protein-coupled receptor kinase 3 -2.0086
RAB26 RAB26, member RAS oncogene family -2.0085
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 -2.0081
CDH8 cadherin 8, type 2 -2.00077
ACSM5 acyl-CoA synthetase medium-chain family member 5 -2.00023