CRCGN015_HEPG2_48H:B23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 5-(4-{2-[methyl(2-pyridinyl)amino]ethoxy}benzyl)-1,3-thiazolidine-2,4-dione 34.95 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

6 genes differentially expressed following the CRCGN015_HEPG2_48H:B23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
KLHL21 kelch-like family member 21 3.102
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 2.82617
EXOSC4 exosome component 4 2.65769
ADO 2-aminoethanethiol (cysteamine) dioxygenase 2.46803

decreased expression

Symbol Name Standardized Value
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -3.06098
CXADR coxsackie virus and adenovirus receptor -3.0358