CRCGN015_HEPG2_48H:C01 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tryptamine 100.0 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

1388 genes differentially expressed following the CRCGN015_HEPG2_48H:C01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 5.18113
UBE2L6 ubiquitin-conjugating enzyme E2L 6 5.14303
HMOX1 heme oxygenase 1 5.04493
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 4.7279
TRIB3 tribbles pseudokinase 3 4.4617
PPOX protoporphyrinogen oxidase 4.41752
VAT1 vesicle amine transport 1 4.29954
CDPF1 cysteine-rich, DPF motif domain containing 1 4.11038
IPO13 importin 13 4.03616
RAP1GAP RAP1 GTPase activating protein 4.02499
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 3.98272
RRAGC Ras-related GTP binding C 3.94799
H2BC12 H2B clustered histone 12 3.92165
INPP1 inositol polyphosphate-1-phosphatase 3.91776
CRELD2 cysteine-rich with EGF-like domains 2 3.87304
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 3.83523
YPEL5 yippee-like 5 (Drosophila) 3.79224
CYB5R1 cytochrome b5 reductase 1 3.78513
GATA3 GATA binding protein 3 3.78513
CTRB2 chymotrypsinogen B2 3.74488
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 3.72682
DHRS7 dehydrogenase/reductase (SDR family) member 7 3.60226
RPL39L ribosomal protein L39-like 3.59326
TRIM13 tripartite motif containing 13 3.57767
NIT1 nitrilase 1 3.54903
LIN37 lin-37 DREAM MuvB core complex component 3.52721
CLCN6 chloride channel, voltage-sensitive 6 3.48131
IGFBP3 insulin-like growth factor binding protein 3 3.48129
ZFP36 ZFP36 ring finger protein 3.47114
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 3.45656
ABHD4 abhydrolase domain containing 4 3.43422
ZFYVE26 zinc finger, FYVE domain containing 26 3.43154
SFXN3 sideroflexin 3 3.3289
TMEM53 transmembrane protein 53 3.32766
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 3.30086
ZNF133 zinc finger protein 133 3.29905
REM1 RAS (RAD and GEM)-like GTP-binding 1 3.29545
SQOR sulfide quinone oxidoreductase 3.29229
JUN jun proto-oncogene 3.27781
RAI2 retinoic acid induced 2 3.27761
MAPK7 mitogen-activated protein kinase 7 3.25539
RTL8A retrotransposon Gag like 8A 3.24648
IAPP islet amyloid polypeptide 3.24495
IQSEC2 IQ motif and Sec7 domain 2 3.22902
SARM1 sterile alpha and TIR motif containing 1 3.2149
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 3.2144
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 3.21324
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 3.20897
OPTN optineurin 3.19226
SQSTM1 sequestosome 1 3.18216
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 3.15553
ANXA4 annexin A4 3.14867
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 3.13943
INS insulin 3.12509
GHRH growth hormone releasing hormone 3.12079
NECAP2 NECAP endocytosis associated 2 3.11777
EMC7 ER membrane protein complex subunit 7 3.11221
FBXL7 F-box and leucine-rich repeat protein 7 3.10716
PEA15 phosphoprotein enriched in astrocytes 15 3.09182
IRF9 interferon regulatory factor 9 3.09166
SARS1 seryl-tRNA synthetase 1 3.08611
H2BC21 H2B clustered histone 21 3.07601
MARK1 MAP/microtubule affinity-regulating kinase 1 3.07428
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 3.06592
CRYBA2 crystallin, beta A2 3.06056
FABP4 fatty acid binding protein 4, adipocyte 3.05725
FILIP1L filamin A interacting protein 1-like 3.04902
IDH3B isocitrate dehydrogenase 3 (NAD+) beta 3.04481
RUFY1 RUN and FYVE domain containing 1 3.04243
BLVRB biliverdin reductase B 3.03747
APOD apolipoprotein D 3.03619
WDR7 WD repeat domain 7 3.03153
FOS FBJ murine osteosarcoma viral oncogene homolog 3.0297
EMC3 ER membrane protein complex subunit 3 3.02919
GPKOW G patch domain and KOW motifs 3.02677
CLPS colipase, pancreatic 3.02119
STX4 syntaxin 4 3.02084
ST7L suppression of tumorigenicity 7 like 3.01189
ORAI3 ORAI calcium release-activated calcium modulator 3 3.00642
WBP2 WW domain binding protein 2 2.99715
TMEM43 transmembrane protein 43 2.99521
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) 2.99249
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 2.98735
WDR13 WD repeat domain 13 2.97821
CELA3B chymotrypsin-like elastase family, member 3B 2.97399
SCGB1D2 secretoglobin, family 1D, member 2 2.9697
MAPKBP1 mitogen-activated protein kinase binding protein 1 2.96788
GUCY1A2 guanylate cyclase 1, soluble, alpha 2 2.96782
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 2.96591
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2.96523
VEGFC vascular endothelial growth factor C 2.96385
CELA2A chymotrypsin-like elastase family, member 2A 2.95131
ACVRL1 activin A receptor type II-like 1 2.94524
SH3GLB1 SH3-domain GRB2-like endophilin B1 2.94238
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.93332
ADRA2B adrenoceptor alpha 2B 2.92471
SNX3 sorting nexin 3 2.92402
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 2.91662
GBE1 glucan (1,4-alpha-), branching enzyme 1 2.90975
FAM114A1 family with sequence similarity 114, member A1 2.90739
MBOAT2 membrane bound O-acyltransferase domain containing 2 2.90647
ZFP36L2 ZFP36 ring finger protein-like 2 2.90159
ATF3 activating transcription factor 3 2.89917
STAP2 signal transducing adaptor family member 2 2.89365
WDR37 WD repeat domain 37 2.87982
GTF2B general transcription factor IIB 2.87478
CTSK cathepsin K 2.87054
SCPEP1 serine carboxypeptidase 1 2.86592
SPG11 spastic paraplegia 11 (autosomal recessive) 2.86355
CDCP1 CUB domain containing protein 1 2.85291
PRR15L proline rich 15-like 2.85249
IL3RA interleukin 3 receptor, alpha (low affinity) 2.84891
SCGB2A2 secretoglobin, family 2A, member 2 2.84647
CIDEC cell death-inducing DFFA-like effector c 2.84475
LY6G6C lymphocyte antigen 6 complex, locus G6C 2.83823
TCN2 transcobalamin II 2.83765
CTRB1 chymotrypsinogen B1 2.83255
CCL14 chemokine (C-C motif) ligand 14 2.81988
PRSS58 protease, serine, 58 2.79519
HOXB1 homeobox B1 2.79423
CELA2B chymotrypsin-like elastase family, member 2B 2.78976
ASIC4 acid sensing (proton gated) ion channel family member 4 2.7842
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 2.77582
SYNPO synaptopodin 2.77285
PNLIP pancreatic lipase 2.77196
GCG glucagon 2.77139
DYNLT1 dynein, light chain, Tctex-type 1 2.7593
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 2.75907
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 2.75824
CTRC chymotrypsin C (caldecrin) 2.75352
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 2.75026
CBY1 chibby homolog 1 (Drosophila) 2.7454
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1 2.74298
UROD uroporphyrinogen decarboxylase 2.73526
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 2.72545
TMBIM1 transmembrane BAX inhibitor motif containing 1 2.72534
DOCK1 dedicator of cytokinesis 1 2.72363
NCKAP1 NCK-associated protein 1 2.72181
IL36R interleukin 36 receptor 2.72151
KLK5 kallikrein-related peptidase 5 2.72069
CSRNP2 cysteine-serine-rich nuclear protein 2 2.71788
KRT3 keratin 3, type II 2.71524
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2 2.71511
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 2.71075
TMEM140 transmembrane protein 140 2.70983
IL15RA interleukin 15 receptor, alpha 2.70863
LDOC1 leucine zipper, down-regulated in cancer 1 2.7073
ARSF arylsulfatase F 2.70663
MMRN1 multimerin 1 2.70461
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.70405
OR10H1 olfactory receptor, family 10, subfamily H, member 1 2.69384
APOBR apolipoprotein B receptor 2.69
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.68972
ABLIM3 actin binding LIM protein family, member 3 2.68653
TNFAIP8L2-SCNM1 TNFAIP8L2-SCNM1 readthrough 2.67869
ZMIZ1 zinc finger, MIZ-type containing 1 2.67783
HCK HCK proto-oncogene, Src family tyrosine kinase 2.67681
FOXJ2 forkhead box J2 2.6764
CIDEA cell death-inducing DFFA-like effector a 2.67578
IER5 immediate early response 5 2.67095
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.66949
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 2.66857
GMPR guanosine monophosphate reductase 2.66259
ZBTB22 zinc finger and BTB domain containing 22 2.66108
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14 2.65807
MSI1 musashi RNA-binding protein 1 2.65735
RTL8C retrotransposon Gag like 8C 2.65571
CPA1 carboxypeptidase A1 (pancreatic) 2.65008
TPSD1 tryptase delta 1 2.65
PTPRT protein tyrosine phosphatase, receptor type, T 2.64675
BECN1 beclin 1, autophagy related 2.64077
ACLY ATP citrate lyase 2.64032
NAGK N-acetylglucosamine kinase 2.63658
GSTA1 glutathione S-transferase alpha 1 2.63507
GDI1 GDP dissociation inhibitor 1 2.63446
FFAR3 free fatty acid receptor 3 2.62721
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 2.62572
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10 2.62505
CUTA cutA divalent cation tolerance homolog (E. coli) 2.61621
KLF4 Kruppel-like factor 4 (gut) 2.61607
SRPX sushi-repeat containing protein, X-linked 2.61559
PLA2G1B phospholipase A2, group IB (pancreas) 2.6137
EHD4 EH-domain containing 4 2.61
ACVR2A activin A receptor, type IIA 2.60822
CLIC2 chloride intracellular channel 2 2.60818
FAM246A family with sequence similarity 246 member A 2.60722
RGS16 regulator of G-protein signaling 16 2.60695
VAC14 Vac14 homolog (S. cerevisiae) 2.60636
CTIF CBP80/20-dependent translation initiation factor 2.6032
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 2.60056
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 2.59863
PITX3 paired-like homeodomain 3 2.59633
HSFX2 heat shock transcription factor family, X linked 2 2.59169
CEP15 centrosomal protein 15 2.58894
TM2D1 TM2 domain containing 1 2.58422
GADD45B growth arrest and DNA-damage-inducible, beta 2.58034
ELF4 E74-like factor 4 (ets domain transcription factor) 2.5774
AMHR2 anti-Mullerian hormone receptor, type II 2.57354
ZNF34 zinc finger protein 34 2.57287
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 2.56858
PRDM12 PR domain containing 12 2.56401
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 2.56158
STX8 syntaxin 8 2.55822
CALHM2 calcium homeostasis modulator 2 2.55788
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 2.55741
ZNF821 zinc finger protein 821 2.55024
BLCAP bladder cancer associated protein 2.54861
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.54769
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 2.54504
NR5A1 nuclear receptor subfamily 5, group A, member 1 2.5416
DUSP28 dual specificity phosphatase 28 2.54059
PANK2 pantothenate kinase 2 2.53755
KIAA0319 KIAA0319 2.53716
CSRNP3 cysteine-serine-rich nuclear protein 3 2.53637
WNT6 wingless-type MMTV integration site family, member 6 2.53598
KISS1 KiSS-1 metastasis-suppressor 2.53499
APOA4 apolipoprotein A-IV 2.53317
JADE2 jade family PHD finger 2 2.53276
WFS1 Wolfram syndrome 1 (wolframin) 2.53271
SYNE3 spectrin repeat containing, nuclear envelope family member 3 2.53211
PHF1 PHD finger protein 1 2.53191
PGRMC2 progesterone receptor membrane component 2 2.53089
HTRA2 HtrA serine peptidase 2 2.5285
OSER1 oxidative stress responsive serine-rich 1 2.52815
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 2.52745
MTMR14 myotubularin related protein 14 2.52422
DIPK1A divergent protein kinase domain 1A 2.5233
GJA3 gap junction protein, alpha 3, 46kDa 2.52199
MOSPD1 motile sperm domain containing 1 2.52194
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 2.51978
UGDH UDP-glucose 6-dehydrogenase 2.51779
IL25 interleukin 25 2.51617
METTL25B methyltransferase like 25B 2.51577
IFI27 interferon, alpha-inducible protein 27 2.51269
IFT27 intraflagellar transport 27 2.51137
TCEAL9 transcription elongation factor A like 9 2.50823
INA internexin neuronal intermediate filament protein, alpha 2.50599
GPR37L1 G protein-coupled receptor 37 like 1 2.50464
SCGB1D1 secretoglobin, family 1D, member 1 2.50293
TSPAN15 tetraspanin 15 2.50271
OXT oxytocin/neurophysin I prepropeptide 2.50241
IL10RA interleukin 10 receptor, alpha 2.50095
MYH9 myosin, heavy chain 9, non-muscle 2.4985
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 2.498
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) 2.49789
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 2.49729
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 2.49638
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) 2.49632
LHFPL2 lipoma HMGIC fusion partner-like 2 2.49442
LY96 lymphocyte antigen 96 2.49331
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 2.48659
STX12 syntaxin 12 2.48454
NT5E 5'-nucleotidase, ecto (CD73) 2.48419
EXD3 exonuclease 3'-5' domain containing 3 2.4829
NVL nuclear VCP-like 2.48194
GBP2 guanylate binding protein 2, interferon-inducible 2.47668
DAAM2 dishevelled associated activator of morphogenesis 2 2.47457
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 2.47383
FIG4 FIG4 phosphoinositide 5-phosphatase 2.47232
CYTH1 cytohesin 1 2.47176
PIGH phosphatidylinositol glycan anchor biosynthesis, class H 2.4692
NXPH3 neurexophilin 3 2.46745
UNC13A unc-13 homolog A (C. elegans) 2.46731
NXPH4 neurexophilin 4 2.46256
KRT32 keratin 32, type I 2.46022
STBD1 starch binding domain 1 2.45797
TTC23 tetratricopeptide repeat domain 23 2.45654
SDC3 syndecan 3 2.45228
SHB Src homology 2 domain containing adaptor protein B 2.45168
TCEA2 transcription elongation factor A (SII), 2 2.44928
PLIN1 perilipin 1 2.44729
TSPO translocator protein (18kDa) 2.44397
ARID5A AT rich interactive domain 5A (MRF1-like) 2.44135
CDKL3 cyclin-dependent kinase-like 3 2.44029
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 2.43811
PRRG3 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) 2.43724
DENND2A DENN/MADD domain containing 2A 2.43685
TXNRD1 thioredoxin reductase 1 2.43496
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 2.43332
RBP3 retinol binding protein 3, interstitial 2.43317
WNT11 wingless-type MMTV integration site family, member 11 2.42987
KANK3 KN motif and ankyrin repeat domains 3 2.42984
CLIP3 CAP-GLY domain containing linker protein 3 2.42136
NRSN2 neurensin 2 2.42001
GDAP1L1 ganglioside induced differentiation associated protein 1-like 1 2.41877
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 2.41252
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2 2.41025
MMRN2 multimerin 2 2.4101
DOC2B double C2-like domains, beta 2.4069
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 2.40463
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 2.40418
CELA3A chymotrypsin-like elastase family, member 3A 2.40275
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 2.40013
HOXA3 homeobox A3 2.39394
NAGLU N-acetylglucosaminidase, alpha 2.39359
IL12RB1 interleukin 12 receptor, beta 1 2.39288
GAS6 growth arrest-specific 6 2.39223
CYTH4 cytohesin 4 2.39128
TSHZ2 teashirt zinc finger homeobox 2 2.38966
OSGIN1 oxidative stress induced growth inhibitor 1 2.38594
HHLA1 HERV-H LTR-associating 1 2.37948
LRRC42 leucine rich repeat containing 42 2.37769
RAB11FIP5 RAB11 family interacting protein 5 (class I) 2.37735
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10 2.37449
OPRD1 opioid receptor, delta 1 2.37174
TH tyrosine hydroxylase 2.37087
STMN2 stathmin 2 2.36947
AHNAK AHNAK nucleoprotein 2.36927
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent) 2.36836
SDCBP syndecan binding protein (syntenin) 2.36671
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) 2.36621
KYAT3 kynurenine aminotransferase 3 2.36461
FAAP20 FA core complex associated protein 20 2.36232
PPIL6 peptidylprolyl isomerase (cyclophilin)-like 6 2.35992
SCN5A sodium channel, voltage gated, type V alpha subunit 2.35958
CCL27 chemokine (C-C motif) ligand 27 2.35729
NDRG4 NDRG family member 4 2.35641
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 2.35636
PRSS23 protease, serine, 23 2.35606
PLPPR4 phospholipid phosphatase related 4 2.35603
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3 2.35493
LARP6 La ribonucleoprotein domain family, member 6 2.35346
TP73 tumor protein p73 2.35226
MTCH1 mitochondrial carrier 1 2.35203
ADGRL4 adhesion G protein-coupled receptor L4 2.35124
CD63 CD63 molecule 2.35014
KIF3C kinesin family member 3C 2.34927
GSTA3 glutathione S-transferase alpha 3 2.34681
NPFFR1 neuropeptide FF receptor 1 2.34551
HPSE2 heparanase 2 (inactive) 2.34277
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 2.33908
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28 2.33757
CRLF2 cytokine receptor-like factor 2 2.33727
STAT5A signal transducer and activator of transcription 5A 2.33697
EXOC1 exocyst complex component 1 2.33267
CSDC2 cold shock domain containing C2, RNA binding 2.33042
AMELY amelogenin, Y-linked 2.33024
H2AC19 H2A clustered histone 19 2.32933
LRRC32 leucine rich repeat containing 32 2.32859
OR3A3 olfactory receptor, family 3, subfamily A, member 3 2.32421
SLC22A17 solute carrier family 22, member 17 2.32298
FBXL8 F-box and leucine-rich repeat protein 8 2.32226
TRIP4 thyroid hormone receptor interactor 4 2.32213
NPTX2 neuronal pentraxin II 2.32144
PRAMEF13 PRAME family member 13 2.31742
TUBAL3 tubulin, alpha-like 3 2.3167
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B 2.31404
MAST4 microtubule associated serine/threonine kinase family member 4 2.31403
PNPLA6 patatin-like phospholipase domain containing 6 2.31381
CXXC4 CXXC finger protein 4 2.31359
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) 2.31012
ENDOU endonuclease, polyU-specific 2.30895
ALAS1 5'-aminolevulinate synthase 1 2.30288
GAL3ST1 galactose-3-O-sulfotransferase 1 2.30246
MOCS1 molybdenum cofactor synthesis 1 2.30163
SLIT3 slit homolog 3 (Drosophila) 2.29887
AMDHD2 amidohydrolase domain containing 2 2.29852
SUCO SUN domain containing ossification factor 2.29817
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha 2.29816
GPR137B G protein-coupled receptor 137B 2.29743
PLPP3 phospholipid phosphatase 3 2.29652
PI4KB phosphatidylinositol 4-kinase, catalytic, beta 2.29576
PFKM phosphofructokinase, muscle 2.29566
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6 2.29511
SYP synaptophysin 2.29455
PLA2G2F phospholipase A2, group IIF 2.2943
HSPA12A heat shock 70kDa protein 12A 2.29221
TMEM35B transmembrane protein 35B 2.29203
SMIM40 small integral membrane protein 40 2.29157
KIF13B kinesin family member 13B 2.29108
QRICH1 glutamine-rich 1 2.28988
BCAN brevican 2.28962
CDIP1 cell death-inducing p53 target 1 2.28819
CAMK1 calcium/calmodulin-dependent protein kinase I 2.28568
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1 2.2856
IL1B interleukin 1, beta 2.284
CLCN7 chloride channel, voltage-sensitive 7 2.28388
EXOSC4 exosome component 4 2.2789
CHN1 chimerin 1 2.27854
MBD1 methyl-CpG binding domain protein 1 2.27694
GPR75 G protein-coupled receptor 75 2.27571
DEPP1 DEPP autophagy regulator 1 2.27265
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 2.26969
EIF1B eukaryotic translation initiation factor 1B 2.26912
MMP2 matrix metallopeptidase 2 2.26644
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 2.26554
CA7 carbonic anhydrase VII 2.26381
AK5 adenylate kinase 5 2.26369
ACE angiotensin I converting enzyme 2.26285
SCARB1 scavenger receptor class B, member 1 2.26261
CRYBG2 crystallin beta-gamma domain containing 2 2.25906
HSPA2 heat shock 70kDa protein 2 2.25879
PAMR1 peptidase domain containing associated with muscle regeneration 1 2.2559
FST follistatin 2.25366
NCSTN nicastrin 2.25255
FKBP6 FK506 binding protein 6, 36kDa 2.25215
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 2.24989
NSFL1C NSFL1 (p97) cofactor (p47) 2.24985
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 2.24886
SST somatostatin 2.24647
CALML3 calmodulin-like 3 2.24517
SHARPIN SHANK-associated RH domain interactor 2.24494
FAM50A family with sequence similarity 50, member A 2.24236
RNF111 ring finger protein 111 2.24218
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 2.24134
ZC2HC1A zinc finger, C2HC-type containing 1A 2.24098
ARL8B ADP-ribosylation factor-like 8B 2.23929
ANXA9 annexin A9 2.23921
TSKU tsukushi, small leucine rich proteoglycan 2.23607
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 2.2334
PDE8B phosphodiesterase 8B 2.23323
MINDY3 MINDY lysine 48 deubiquitinase 3 2.23292
WNT7A wingless-type MMTV integration site family, member 7A 2.22825
ACR acrosin 2.22795
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A 2.22617
WBP1L WW domain binding protein 1-like 2.22503
MEOX2 mesenchyme homeobox 2 2.22364
NOTCH2NLB notch 2 N-terminal like B 2.21958
VTCN1 V-set domain containing T cell activation inhibitor 1 2.21811
TFE3 transcription factor binding to IGHM enhancer 3 2.215
ZBTB40 zinc finger and BTB domain containing 40 2.2147
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 2.21453
NR4A1 nuclear receptor subfamily 4, group A, member 1 2.21402
FAM110B family with sequence similarity 110, member B 2.21359
CDH5 cadherin 5, type 2 (vascular endothelium) 2.21336
SCGB2A1 secretoglobin, family 2A, member 1 2.21284
MPST mercaptopyruvate sulfurtransferase 2.2118
ANGPTL2 angiopoietin-like 2 2.21113
MAN2B2 mannosidase, alpha, class 2B, member 2 2.21111
RGS9BP regulator of G protein signaling 9 binding protein 2.20928
EHD2 EH-domain containing 2 2.20712
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 2.20704
S100A5 S100 calcium binding protein A5 2.20334
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 2.20333
AP3S2 adaptor-related protein complex 3, sigma 2 subunit 2.20332
SDF2 stromal cell-derived factor 2 2.20277
OXTR oxytocin receptor 2.20251
MLPH melanophilin 2.20203
FGF23 fibroblast growth factor 23 2.202
IL20RA interleukin 20 receptor, alpha 2.20101
TOMM34 translocase of outer mitochondrial membrane 34 2.20005
TMSB15C thymosin beta 15C 2.19928
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6 2.19685
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 2.19621
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 2.19531
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) 2.19493
KCTD17 potassium channel tetramerization domain containing 17 2.19403
NECAB2 N-terminal EF-hand calcium binding protein 2 2.19383
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 2.19283
CCDC92 coiled-coil domain containing 92 2.19241
TENT4A terminal nucleotidyltransferase 4A 2.19182
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 2.19135
YJU2B YJU2 splicing factor homolog B 2.19116
TDRD12 tudor domain containing 12 2.19097
GPR132 G protein-coupled receptor 132 2.19086
PLPP2 phospholipid phosphatase 2 2.18872
DAGLA diacylglycerol lipase, alpha 2.18518
RAB5IF RAB5 interacting factor 2.18471
RASL10A RAS-like, family 10, member A 2.1841
TTLL12 tubulin tyrosine ligase-like family member 12 2.18408
DIPK2B divergent protein kinase domain 2B 2.18311
EHF ets homologous factor 2.18305
BDKRB1 bradykinin receptor B1 2.18285
RNF25 ring finger protein 25 2.18083
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 2.17992
CRYBB1 crystallin, beta B1 2.17919
LRFN3 leucine rich repeat and fibronectin type III domain containing 3 2.17901
GJA4 gap junction protein, alpha 4, 37kDa 2.17858
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase) 2.17808
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 2.17695
ILKAP integrin-linked kinase-associated serine/threonine phosphatase 2.17468
RAB29 RAB29, member RAS oncogene family 2.17389
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 2.17275
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 2.17218
WDR91 WD repeat domain 91 2.17171
ARHGAP29 Rho GTPase activating protein 29 2.17036
PTPRE protein tyrosine phosphatase, receptor type, E 2.17015
SSTR3 somatostatin receptor 3 2.1692
MXI1 MAX interactor 1, dimerization protein 2.16803
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 2.16749
CREB3L4 cAMP responsive element binding protein 3-like 4 2.16742
PRAMEF12 PRAME family member 12 2.16724
TESK1 testis-specific kinase 1 2.16682
MAB21L4 mab-21 like 4 2.166
GPNMB glycoprotein (transmembrane) nmb 2.16558
SEC61G Sec61 gamma subunit 2.16556
SNCG synuclein, gamma (breast cancer-specific protein 1) 2.16346
KRT6B keratin 6B, type II 2.16129
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 2.16032
SOCS2 suppressor of cytokine signaling 2 2.15868
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 2.15799
CHRM4 cholinergic receptor, muscarinic 4 2.15746
ATOSB atos homolog B 2.15589
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 2.15558
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 2.15274
SEZ6L2 seizure related 6 homolog (mouse)-like 2 2.15204
SLC67A1 solute carrier family 67 member 1 2.14875
ZSWIM8 zinc finger, SWIM-type containing 8 2.14859
GBA1 glucosylceramidase beta 1 2.14786
PTPRN protein tyrosine phosphatase, receptor type, N 2.14773
RNF187 ring finger protein 187 2.14749
UPK1A uroplakin 1A 2.14609
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 2.14539
TNXB tenascin XB 2.14462
LRRN2 leucine rich repeat neuronal 2 2.14336
AQP7 aquaporin 7 2.14281
PNLIPRP1 pancreatic lipase-related protein 1 2.14078
SNAI2 snail family zinc finger 2 2.13997
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 2.13993
EMX1 empty spiracles homeobox 1 2.1394
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 2.13934
DNAL4 dynein, axonemal, light chain 4 2.13897
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 2.13885
CAB39L calcium binding protein 39-like 2.1364
RUSC2 RUN and SH3 domain containing 2 2.13594
SOD3 superoxide dismutase 3, extracellular 2.13566
AP1M2 adaptor-related protein complex 1, mu 2 subunit 2.13534
ARHGAP9 Rho GTPase activating protein 9 2.13512
MMP27 matrix metallopeptidase 27 2.13348
ZSCAN9 zinc finger and SCAN domain containing 9 2.13267
TP53I3 tumor protein p53 inducible protein 3 2.13228
REC8 REC8 meiotic recombination protein 2.13012
RAB43 RAB43, member RAS oncogene family 2.12743
PTP4A3 protein tyrosine phosphatase type IVA, member 3 2.12729
ADAM9 ADAM metallopeptidase domain 9 2.12558
TLN1 talin 1 2.12544
MTSS2 MTSS I-BAR domain containing 2 2.12508
GATA6 GATA binding protein 6 2.1243
GBX2 gastrulation brain homeobox 2 2.12394
CRISP3 cysteine-rich secretory protein 3 2.1227
SNAP29 synaptosomal-associated protein, 29kDa 2.12091
KRT24 keratin 24, type I 2.11978
INHBB inhibin, beta B 2.11978
FAM13B family with sequence similarity 13, member B 2.11887
CABP2 calcium binding protein 2 2.11881
FGF5 fibroblast growth factor 5 2.11868
LPAR1 lysophosphatidic acid receptor 1 2.11867
CD34 CD34 molecule 2.11851
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 2.11809
CD36 CD36 molecule (thrombospondin receptor) 2.11795
GUCA2B guanylate cyclase activator 2B (uroguanylin) 2.1163
PDGFD platelet derived growth factor D 2.11548
CCN5 cellular communication network factor 5 2.111
SOX13 SRY (sex determining region Y)-box 13 2.10904
PDE2A phosphodiesterase 2A, cGMP-stimulated 2.10891
ANO2 anoctamin 2, calcium activated chloride channel 2.10788
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 2.10517
HS1BP3 HCLS1 binding protein 3 2.10436
FAM90A1 family with sequence similarity 90, member A1 2.10391
DCAF8 DDB1 and CUL4 associated factor 8 2.10353
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 2.10338
HMGXB3 HMG box domain containing 3 2.10311
USP3 ubiquitin specific peptidase 3 2.10095
APOL3 apolipoprotein L, 3 2.09699
FABP3 fatty acid binding protein 3, muscle and heart 2.09698
FEM1C fem-1 homolog c (C. elegans) 2.09694
RAP1A RAP1A, member of RAS oncogene family 2.09654
IFT57 intraflagellar transport 57 2.09533
POFUT2 protein O-fucosyltransferase 2 2.09457
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17 2.09388
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 2.09354
TMEM165 transmembrane protein 165 2.09216
LPGAT1 lysophosphatidylglycerol acyltransferase 1 2.09211
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3 2.08905
MTSS1 metastasis suppressor 1 2.08879
TMPRSS5 transmembrane protease, serine 5 2.08878
RND3 Rho family GTPase 3 2.08856
CDSN corneodesmosin 2.08797
SLC12A8 solute carrier family 12, member 8 2.08692
GBX1 gastrulation brain homeobox 1 2.08628
LPAR3 lysophosphatidic acid receptor 3 2.08265
PCSK2 proprotein convertase subtilisin/kexin type 2 2.08123
NUPR1 nuclear protein, transcriptional regulator, 1 2.07828
TREH trehalase (brush-border membrane glycoprotein) 2.07753
THBD thrombomodulin 2.07509
BNC1 basonuclin 1 2.07238
SCG5 secretogranin V 2.07189
CREBL2 cAMP responsive element binding protein-like 2 2.07165
DDRGK1 DDRGK domain containing 1 2.07037
HDAC9 histone deacetylase 9 2.06939
CDH22 cadherin 22, type 2 2.06726
NPY4R2 neuropeptide Y receptor Y4-2 2.06669
MLH1 mutL homolog 1 2.06658
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 2.06646
GORASP1 golgi reassembly stacking protein 1, 65kDa 2.06633
MYO1D myosin ID 2.06594
TTLL1 tubulin tyrosine ligase-like family member 1 2.0625
TTLL7 tubulin tyrosine ligase-like family member 7 2.06105
PARP6 poly (ADP-ribose) polymerase family, member 6 2.06096
BRME1 break repair meiotic recombinase recruitment factor 1 2.06002
OR1E1 olfactory receptor, family 1, subfamily E, member 1 2.05998
CEMP1 cementum protein 1 2.05964
NOVA2 neuro-oncological ventral antigen 2 2.05908
LYRM1 LYR motif containing 1 2.05602
GATA1 GATA binding protein 1 (globin transcription factor 1) 2.05597
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 2.05521
PKD2L1 polycystic kidney disease 2-like 1 2.05423
FLNC filamin C, gamma 2.05296
HLX H2.0-like homeobox 2.04993
CGRRF1 cell growth regulator with ring finger domain 1 2.0487
MYCT1 myc target 1 2.04855
HSPA6 heat shock 70kDa protein 6 (HSP70B') 2.04796
LONP1 lon peptidase 1, mitochondrial 2.04655
EMILIN2 elastin microfibril interfacer 2 2.04654
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 2.04567
MVK mevalonate kinase 2.04412
PLXNC1 plexin C1 2.04281
ZNF250 zinc finger protein 250 2.04253
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.04075
LRP2 low density lipoprotein receptor-related protein 2 2.04071
NOX4 NADPH oxidase 4 2.04071
RAB5B RAB5B, member RAS oncogene family 2.04
TMPRSS3 transmembrane protease, serine 3 2.03998
PMM1 phosphomannomutase 1 2.03979
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 2.03916
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 2.03837
ATG14 autophagy related 14 2.03783
STN1 STN1 subunit of CST complex 2.03723
GPR27 G protein-coupled receptor 27 2.03431
ACTN3 actinin, alpha 3 (gene/pseudogene) 2.03114
GFRA4 GDNF family receptor alpha 4 2.02947
ADRA2A adrenoceptor alpha 2A 2.02826
AKR1C3 aldo-keto reductase family 1, member C3 2.02768
ADIPOQ adiponectin, C1Q and collagen domain containing 2.02754
RASL12 RAS-like, family 12 2.02687
MOK MOK protein kinase 2.02665
EPS8L1 EPS8-like 1 2.02649
SLC38A6 solute carrier family 38, member 6 2.02452
PPP1R15A protein phosphatase 1, regulatory subunit 15A 2.02436
RNF19B ring finger protein 19B 2.02366
LMOD1 leiomodin 1 (smooth muscle) 2.02286
RHOQ ras homolog family member Q 2.02282
MED9 mediator complex subunit 9 2.02237
WASHC3 WASH complex subunit 3 2.02147
MAP3K5 mitogen-activated protein kinase kinase kinase 5 2.02098
DEDD death effector domain containing 2.02057
ARL4C ADP-ribosylation factor-like 4C 2.02046
EMCN endomucin 2.02037
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.01976
NOTCH4 notch 4 2.01873
SPINT1 serine peptidase inhibitor, Kunitz type 1 2.01687
MRAS muscle RAS oncogene homolog 2.01682
GREM2 gremlin 2, DAN family BMP antagonist 2.01575
MFSD6 major facilitator superfamily domain containing 6 2.01411
LZTR1 leucine-zipper-like transcription regulator 1 2.01406
MX1 MX dynamin-like GTPase 1 2.01379
CLCA2 chloride channel accessory 2 2.01193
PROCR protein C receptor, endothelial 2.01084
PPP1R13B protein phosphatase 1, regulatory subunit 13B 2.01069
KLF15 Kruppel-like factor 15 2.00955
TMOD1 tropomodulin 1 2.00894
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 2.00576
GDF3 growth differentiation factor 3 2.00542
SSPN sarcospan 2.00496
NCF2 neutrophil cytosolic factor 2 2.00377
CD40 CD40 molecule, TNF receptor superfamily member 5 2.00244
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated 2.00216
ACO2 aconitase 2, mitochondrial 2.00122

decreased expression

Symbol Name Standardized Value
TOP2A topoisomerase (DNA) II alpha 170kDa -7.14812
CDC20 cell division cycle 20 -7.12491
RPS4Y1 ribosomal protein S4, Y-linked 1 -6.57901
CCNA2 cyclin A2 -6.02023
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -5.66341
TPX2 TPX2, microtubule-associated -5.65341
S100P S100 calcium binding protein P -5.46808
PLK1 polo-like kinase 1 -5.35784
CCNB1 cyclin B1 -5.10011
KIF20A kinesin family member 20A -5.08963
KIF4A kinesin family member 4A -5.07153
BIRC5 baculoviral IAP repeat containing 5 -5.06662
CCNB2 cyclin B2 -4.96245
MCM10 minichromosome maintenance complex component 10 -4.94353
RACGAP1 Rac GTPase activating protein 1 -4.91935
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -4.91583
CDC45 cell division cycle 45 -4.9071
TTK TTK protein kinase -4.87052
CENPE centromere protein E, 312kDa -4.8158
APOA2 apolipoprotein A-II -4.78131
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -4.58461
KIF15 kinesin family member 15 -4.54009
ASF1B anti-silencing function 1B histone chaperone -4.5232
TTF1 transcription termination factor, RNA polymerase I -4.38931
NAE1 NEDD8 activating enzyme E1 subunit 1 -4.38108
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -4.35493
NUP85 nucleoporin 85kDa -4.2744
LMNB1 lamin B1 -4.25811
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -4.25342
B4GAT1 beta-1,4-glucuronyltransferase 1 -4.24536
HMMR hyaluronan-mediated motility receptor (RHAMM) -4.20315
DBF4 DBF4 zinc finger -4.13351
NDC80 NDC80 kinetochore complex component -4.1261
KIF11 kinesin family member 11 -4.11211
TRIP13 thyroid hormone receptor interactor 13 -4.05759
CDK1 cyclin-dependent kinase 1 -4.01452
RFC3 replication factor C (activator 1) 3, 38kDa -4.0076
PRPF4 pre-mRNA processing factor 4 -3.99711
MKI67 marker of proliferation Ki-67 -3.97885
KIF14 kinesin family member 14 -3.97038
MCM6 minichromosome maintenance complex component 6 -3.96616
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta -3.93584
SHCBP1 SHC SH2-domain binding protein 1 -3.91985
CDCA4 cell division cycle associated 4 -3.88817
COG7 component of oligomeric golgi complex 7 -3.87583
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -3.86216
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -3.85393
CSE1L CSE1 chromosome segregation 1-like (yeast) -3.84901
ATAD2 ATPase family, AAA domain containing 2 -3.84484
VRK1 vaccinia related kinase 1 -3.84449
NCAPG2 non-SMC condensin II complex, subunit G2 -3.78835
TDP1 tyrosyl-DNA phosphodiesterase 1 -3.7692
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -3.76249
FANCC Fanconi anemia, complementation group C -3.75328
C5 complement component 5 -3.74451
ERCC6L excision repair cross-complementation group 6-like -3.73204
PROM1 prominin 1 -3.72732
PTTG1 pituitary tumor-transforming 1 -3.71832
SPOUT1 SPOUT domain containing methyltransferase 1 -3.68183
GINS2 GINS complex subunit 2 (Psf2 homolog) -3.67875
LBR lamin B receptor -3.65775
PRC1 protein regulator of cytokinesis 1 -3.65204
CKAP5 cytoskeleton associated protein 5 -3.64938
FEN1 flap structure-specific endonuclease 1 -3.62378
HSPD1 heat shock 60kDa protein 1 (chaperonin) -3.61939
SEH1L SEH1-like (S. cerevisiae) -3.61596
NUSAP1 nucleolar and spindle associated protein 1 -3.58152
MTPAP mitochondrial poly(A) polymerase -3.56275
CENPA centromere protein A -3.55306
TCERG1 transcription elongation regulator 1 -3.53004
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E -3.52322
RFWD3 ring finger and WD repeat domain 3 -3.52144
RBM28 RNA binding motif protein 28 -3.51182
ZWILCH zwilch kinetochore protein -3.50313
KIF18A kinesin family member 18A -3.50117
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -3.49286
SUZ12 SUZ12 polycomb repressive complex 2 subunit -3.45719
ASDURF ASNSD1 upstream open reading frame -3.44997
CENPN centromere protein N -3.44317
PSIP1 PC4 and SFRS1 interacting protein 1 -3.43296
CEP55 centrosomal protein 55kDa -3.42657
FBXO5 F-box protein 5 -3.42601
OIP5 Opa interacting protein 5 -3.41993
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) -3.41182
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -3.40841
CEP76 centrosomal protein 76kDa -3.38478
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -3.38423
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -3.37719
AURKA aurora kinase A -3.3765
BRCA1 breast cancer 1, early onset -3.37504
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 -3.37341
NAT10 N-acetyltransferase 10 (GCN5-related) -3.3733
SBNO1 strawberry notch homolog 1 (Drosophila) -3.35749
SLC35F2 solute carrier family 35, member F2 -3.35315
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -3.35059
BLM Bloom syndrome, RecQ helicase-like -3.34777
NPR2 natriuretic peptide receptor 2 -3.34304
MCM7 minichromosome maintenance complex component 7 -3.33274
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa -3.32651
POLR1A polymerase (RNA) I polypeptide A, 194kDa -3.32174
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.304
MIS18A MIS18 kinetochore protein A -3.29871
ABT1 activator of basal transcription 1 -3.28555
HJURP Holliday junction recognition protein -3.25996
NCK1 NCK adaptor protein 1 -3.255
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -3.25391
DEPDC1 DEP domain containing 1 -3.25226
TRAM2 translocation associated membrane protein 2 -3.24497
SLC25A40 solute carrier family 25, member 40 -3.2389
NEK2 NIMA-related kinase 2 -3.22374
THOP1 thimet oligopeptidase 1 -3.21663
VDAC1 voltage-dependent anion channel 1 -3.21657
CDCA3 cell division cycle associated 3 -3.21436
USP1 ubiquitin specific peptidase 1 -3.21177
MTIF2 mitochondrial translational initiation factor 2 -3.20749
DHFR dihydrofolate reductase -3.20538
NIP7 NIP7, nucleolar pre-rRNA processing protein -3.19988
CKAP2 cytoskeleton associated protein 2 -3.19259
PRPF39 pre-mRNA processing factor 39 -3.18752
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -3.18298
ANKRD40 ankyrin repeat domain 40 -3.18113
H2AZ2 H2A.Z variant histone 2 -3.17766
NUP160 nucleoporin 160kDa -3.17623
CDKN3 cyclin-dependent kinase inhibitor 3 -3.17612
THOC2 THO complex 2 -3.17289
NME1 NME/NM23 nucleoside diphosphate kinase 1 -3.17042
TIPIN TIMELESS interacting protein -3.16984
TRIM28 tripartite motif containing 28 -3.16977
FANCI Fanconi anemia, complementation group I -3.16686
IPO5 importin 5 -3.16684
STMN1 stathmin 1 -3.16317
HMGB1 high mobility group box 1 -3.15682
CEP63 centrosomal protein 63kDa -3.15644
LAX1 lymphocyte transmembrane adaptor 1 -3.14477
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase -3.13763
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) -3.13484
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -3.12983
NUP93 nucleoporin 93kDa -3.12381
CDC6 cell division cycle 6 -3.12066
RRM1 ribonucleotide reductase M1 -3.11865
KIF18B kinesin family member 18B -3.11401
GPHN gephyrin -3.10808
PDE3B phosphodiesterase 3B, cGMP-inhibited -3.10464
MRPS7 mitochondrial ribosomal protein S7 -3.10443
EXO1 exonuclease 1 -3.10426
POLR1G RNA polymerase I subunit G -3.10054
MBIP MAP3K12 binding inhibitory protein 1 -3.10013
LIPT1 lipoyltransferase 1 -3.09637
PRMT1 protein arginine methyltransferase 1 -3.09084
LOC112694756 uncharaterized LOC112694756 -3.09042
NEIL3 nei endonuclease VIII-like 3 (E. coli) -3.09038
PLK4 polo-like kinase 4 -3.08614
CTCF CCCTC-binding factor (zinc finger protein) -3.08569
PAK1IP1 PAK1 interacting protein 1 -3.08244
PCLAF PCNA clamp associated factor -3.07972
DSG2 desmoglein 2 -3.07767
MRPL3 mitochondrial ribosomal protein L3 -3.0758
NKRF NFKB repressing factor -3.07201
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 -3.0556
ZNF551 zinc finger protein 551 -3.04536
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -3.03559
APOH apolipoprotein H (beta-2-glycoprotein I) -3.03518
CDCA8 cell division cycle associated 8 -3.02769
ORC6 origin recognition complex, subunit 6 -3.02517
BUD23 BUD23 rRNA methyltransferase and ribosome maturation factor -3.02504
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa -3.02087
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -3.0189
RFC2 replication factor C (activator 1) 2, 40kDa -3.01844
POMK protein-O-mannose kinase -3.01599
ZNF428 zinc finger protein 428 -3.01534
DNA2 DNA replication helicase/nuclease 2 -3.01431
TEFM transcription elongation factor, mitochondrial -2.99896
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) -2.9953
SPDL1 spindle apparatus coiled-coil protein 1 -2.99467
KIFC1 kinesin family member C1 -2.99109
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 -2.98777
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 -2.98675
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -2.98482
GLG1 golgi glycoprotein 1 -2.97799
BRIX1 BRX1, biogenesis of ribosomes -2.97178
MCM3 minichromosome maintenance complex component 3 -2.9677
UBE2S ubiquitin-conjugating enzyme E2S -2.96435
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) -2.96349
GMDS GDP-mannose 4,6-dehydratase -2.95384
NLE1 notchless homolog 1 (Drosophila) -2.95175
KNOP1 lysine-rich nucleolar protein 1 -2.94908
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1 -2.93801
RRM2 ribonucleotide reductase M2 -2.93425
STX17 syntaxin 17 -2.93406
OBI1 ORC ubiquitin ligase 1 -2.93375
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 -2.93098
CYBA cytochrome b-245, alpha polypeptide -2.92823
U2SURP U2 snRNP-associated SURP domain containing -2.92347
RMI1 RecQ mediated genome instability 1 -2.91984
YEATS4 YEATS domain containing 4 -2.91631
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -2.91383
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 -2.91034
PECR peroxisomal trans-2-enoyl-CoA reductase -2.9083
RBMX RNA binding motif protein, X-linked -2.9076
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa -2.90469
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 -2.90289
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 -2.89871
NCAPH non-SMC condensin I complex, subunit H -2.89349
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.89259
KIF23 kinesin family member 23 -2.89204
MSH2 mutS homolog 2 -2.8909
DPH2 DPH2 homolog (S. cerevisiae) -2.88712
COBL cordon-bleu WH2 repeat protein -2.88459
ATP5MF ATP synthase membrane subunit f -2.87985
SPTAN1 spectrin, alpha, non-erythrocytic 1 -2.87397
USP21 ubiquitin specific peptidase 21 -2.87106
POLR1F RNA polymerase I subunit F -2.86667
TK1 thymidine kinase 1, soluble -2.86504
TEX10 testis expressed 10 -2.86157
JPT1 Jupiter microtubule associated homolog 1 -2.86147
LBHD1 LBH domain containing 1 -2.85993
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -2.85668
BANF1 barrier to autointegration factor 1 -2.84944
CTR9 CTR9, Paf1/RNA polymerase II complex component -2.84784
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae) -2.84489
ANAPC15 anaphase promoting complex subunit 15 -2.84296
S100B S100 calcium binding protein B -2.83937
MYCBP MYC binding protein -2.83904
PM20D1 peptidase M20 domain containing 1 -2.83626
SPAG5 sperm associated antigen 5 -2.835
KYAT1 kynurenine aminotransferase 1 -2.83458
CDC37L1 cell division cycle 37-like 1 -2.82298
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa -2.81474
SDHAF3 succinate dehydrogenase complex assembly factor 3 -2.81139
BORA bora, aurora kinase A activator -2.80978
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -2.80887
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 -2.80827
CASP8AP2 caspase 8 associated protein 2 -2.8062
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -2.80578
HNRNPF heterogeneous nuclear ribonucleoprotein F -2.80442
ARPC5L actin related protein 2/3 complex, subunit 5-like -2.80035
RCOR1 REST corepressor 1 -2.79918
IFITM2 interferon induced transmembrane protein 2 -2.79907
NOL11 nucleolar protein 11 -2.79497
FYN FYN proto-oncogene, Src family tyrosine kinase -2.79232
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -2.79217
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae) -2.7919
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -2.78976
MSL2 male-specific lethal 2 homolog (Drosophila) -2.78412
AKIRIN1 akirin 1 -2.78186
XPO1 exportin 1 -2.7792
SEPTIN6 septin 6 -2.77391
SLC39A7 solute carrier family 39 (zinc transporter), member 7 -2.76994
MAK16 MAK16 homolog (S. cerevisiae) -2.76802
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 -2.75402
EIF4E eukaryotic translation initiation factor 4E -2.74414
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -2.74241
SARS2 seryl-tRNA synthetase 2, mitochondrial -2.73786
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) -2.73545
RNMT RNA (guanine-7-) methyltransferase -2.73525
AGMAT agmatine ureohydrolase (agmatinase) -2.73017
PUS3 pseudouridylate synthase 3 -2.72925
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -2.72894
AFG3L2 AFG3-like AAA ATPase 2 -2.72762
AHCTF1 AT hook containing transcription factor 1 -2.72289
CAPRIN1 cell cycle associated protein 1 -2.72279
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme -2.7227
CCNF cyclin F -2.71863
ZNF184 zinc finger protein 184 -2.71536
BZW1 basic leucine zipper and W2 domains 1 -2.71149
SRSF3 serine/arginine-rich splicing factor 3 -2.706
MPHOSPH9 M-phase phosphoprotein 9 -2.70344
HAUS6 HAUS augmin-like complex, subunit 6 -2.699
ACTR3B ARP3 actin-related protein 3 homolog B (yeast) -2.6971
ENTR1 endosome associated trafficking regulator 1 -2.69519
RPAIN RPA interacting protein -2.69374
BCCIP BRCA2 and CDKN1A interacting protein -2.69372
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -2.69205
HMGA2 high mobility group AT-hook 2 -2.69183
CRTAM cytotoxic and regulatory T cell molecule -2.68117
GEMIN6 gem (nuclear organelle) associated protein 6 -2.67863
NUTF2 nuclear transport factor 2 -2.67824
TROAP trophinin associated protein -2.67229
PUS7 pseudouridylate synthase 7 (putative) -2.6713
CHEK1 checkpoint kinase 1 -2.66665
ELOVL6 ELOVL fatty acid elongase 6 -2.6662
HMGB2 high mobility group box 2 -2.66151
TRAPPC8 trafficking protein particle complex 8 -2.66078
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -2.65557
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H -2.65226
CD320 CD320 molecule -2.64672
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.6435
UBE2C ubiquitin-conjugating enzyme E2C -2.64197
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -2.6391
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.63655
FRAT2 frequently rearranged in advanced T-cell lymphomas 2 -2.63296
NUP37 nucleoporin 37kDa -2.63193
EIF5B eukaryotic translation initiation factor 5B -2.63016
TMEM185B transmembrane protein 185B -2.62167
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.62093
MRPL16 mitochondrial ribosomal protein L16 -2.6156
LUC7L3 LUC7-like 3 (S. cerevisiae) -2.61092
LIN7C lin-7 homolog C (C. elegans) -2.6107
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae) -2.60848
CENPF centromere protein F, 350/400kDa -2.60199
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) -2.60099
PAQR3 progestin and adipoQ receptor family member III -2.59916
ARMC6 armadillo repeat containing 6 -2.59519
ENOPH1 enolase-phosphatase 1 -2.59313
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 -2.58923
NUBPL nucleotide binding protein-like -2.58749
DONSON downstream neighbor of SON -2.58661
KNTC1 kinetochore associated 1 -2.57844
SMC4 structural maintenance of chromosomes 4 -2.57748
MDN1 MDN1, midasin homolog (yeast) -2.57391
CRIPT cysteine-rich PDZ-binding protein -2.57358
CRLF3 cytokine receptor-like factor 3 -2.57233
WDHD1 WD repeat and HMG-box DNA binding protein 1 -2.56914
COL2A1 collagen, type II, alpha 1 -2.56208
ZNF761 zinc finger protein 761 -2.5617
PMPCA peptidase (mitochondrial processing) alpha -2.56102
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 -2.56014
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -2.55894
KAT7 K(lysine) acetyltransferase 7 -2.55827
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal) -2.5565
HAUS4 HAUS augmin-like complex, subunit 4 -2.55359
EXOSC9 exosome component 9 -2.55039
NEMF nuclear export mediator factor -2.54898
ZBTB39 zinc finger and BTB domain containing 39 -2.54822
ZBTB11 zinc finger and BTB domain containing 11 -2.54814
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -2.54796
BLMH bleomycin hydrolase -2.54627
RSAD1 radical S-adenosyl methionine domain containing 1 -2.54577
NCAPG non-SMC condensin I complex, subunit G -2.54448
INTS13 integrator complex subunit 13 -2.5415
MSH6 mutS homolog 6 -2.53707
PIMREG PICALM interacting mitotic regulator -2.53612
SIRPG signal-regulatory protein gamma -2.53349
FKBP3 FK506 binding protein 3, 25kDa -2.53297
RBM14-RBM4 RBM14-RBM4 readthrough -2.53263
IPO7 importin 7 -2.5308
ELAVL1 ELAV like RNA binding protein 1 -2.52807
POU2F1 POU class 2 homeobox 1 -2.52727
NOLC1 nucleolar and coiled-body phosphoprotein 1 -2.52701
LRIG3 leucine-rich repeats and immunoglobulin-like domains 3 -2.52672
RNASE7 ribonuclease, RNase A family, 7 -2.52348
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase -2.51934
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast) -2.51651
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -2.51201
RINT1 RAD50 interactor 1 -2.50667
COA4 cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) -2.50576
UXT ubiquitously-expressed, prefoldin-like chaperone -2.50445
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -2.50407
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -2.49888
MCM5 minichromosome maintenance complex component 5 -2.49826
RPAP3 RNA polymerase II associated protein 3 -2.49111
IL1RAP interleukin 1 receptor accessory protein -2.48939
ZNF443 zinc finger protein 443 -2.48929
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha -2.48837
GEMIN2 gem (nuclear organelle) associated protein 2 -2.48765
AKR1D1 aldo-keto reductase family 1, member D1 -2.48717
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -2.4867
PNN pinin, desmosome associated protein -2.48411
GTPBP4 GTP binding protein 4 -2.48084
COASY CoA synthase -2.48066
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant -2.48034
NELFB negative elongation factor complex member B -2.4728
GEMIN4 gem (nuclear organelle) associated protein 4 -2.47184
SCRG1 stimulator of chondrogenesis 1 -2.47136
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1 -2.46716
CCNJ cyclin J -2.46638
RBM25 RNA binding motif protein 25 -2.46505
CLEC11A C-type lectin domain family 11, member A -2.46179
TFDP1 transcription factor Dp-1 -2.46034
ANKRD49 ankyrin repeat domain 49 -2.45934
HMGB3 high mobility group box 3 -2.45851
COQ3 coenzyme Q3 methyltransferase -2.45705
COL9A3 collagen, type IX, alpha 3 -2.45703
AATF apoptosis antagonizing transcription factor -2.4529
BCLAF1 BCL2-associated transcription factor 1 -2.45099
RPS26 ribosomal protein S26 -2.44738
VCPKMT valosin containing protein lysine (K) methyltransferase -2.44673
CDK2 cyclin-dependent kinase 2 -2.4464
MTF2 metal response element binding transcription factor 2 -2.44612
MRPL42 mitochondrial ribosomal protein L42 -2.4456
ZNF134 zinc finger protein 134 -2.4437
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) -2.44308
NCBP2 nuclear cap binding protein subunit 2, 20kDa -2.44214
OGDHL oxoglutarate dehydrogenase-like -2.4406
NMD3 NMD3 ribosome export adaptor -2.43894
SSRP1 structure specific recognition protein 1 -2.43815
BUB1 BUB1 mitotic checkpoint serine/threonine kinase -2.43449
ADGRA3 adhesion G protein-coupled receptor A3 -2.43307
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -2.43099
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -2.43063
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 -2.43014
FCHSD2 FCH and double SH3 domains 2 -2.4291
FXN frataxin -2.42901
PRUNE1 prune exopolyphosphatase 1 -2.42811
TOMM70 translocase of outer mitochondrial membrane 70 -2.42715
IFITM1 interferon induced transmembrane protein 1 -2.42679
HOXC10 homeobox C10 -2.42392
F9 coagulation factor IX -2.4239
HEATR1 HEAT repeat containing 1 -2.4234
TFAM transcription factor A, mitochondrial -2.42339
SAC3D1 SAC3 domain containing 1 -2.42324
DSN1 DSN1, MIS12 kinetochore complex component -2.41712
AURKB aurora kinase B -2.41455
CD19 CD19 molecule -2.4133
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) -2.41264
PFAS phosphoribosylformylglycinamidine synthase -2.4106
LDLRAP1 low density lipoprotein receptor adaptor protein 1 -2.40909
CBX3 chromobox homolog 3 -2.40762
SEPHS1 selenophosphate synthetase 1 -2.40549
MRPL17 mitochondrial ribosomal protein L17 -2.40014
NFYB nuclear transcription factor Y, beta -2.39813
SPOP speckle-type POZ protein -2.39636
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa -2.3959
WDR43 WD repeat domain 43 -2.39339
PRPF19 pre-mRNA processing factor 19 -2.39321
SRP54 signal recognition particle 54kDa -2.39299
PUM2 pumilio RNA-binding family member 2 -2.39212
DUSP14 dual specificity phosphatase 14 -2.39154
CARMIL1 capping protein regulator and myosin 1 linker 1 -2.39116
ZNF146 zinc finger protein 146 -2.39079
HAL histidine ammonia-lyase -2.38958
ARMC1 armadillo repeat containing 1 -2.38849
KDM1A lysine (K)-specific demethylase 1A -2.38741
ZNF107 zinc finger protein 107 -2.38695
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.38487
KIF22 kinesin family member 22 -2.38442
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -2.38198
HPD 4-hydroxyphenylpyruvate dioxygenase -2.3767
ZDHHC6 zinc finger, DHHC-type containing 6 -2.37651
HMGN2 high mobility group nucleosomal binding domain 2 -2.37524
MRPL12 mitochondrial ribosomal protein L12 -2.36963
RTL10 retrotransposon Gag like 10 -2.36958
LIME1 Lck interacting transmembrane adaptor 1 -2.36949
BAG4 BCL2-associated athanogene 4 -2.3662
TRMT5 tRNA methyltransferase 5 -2.36481
SH2B2 SH2B adaptor protein 2 -2.36474
KDSR 3-ketodihydrosphingosine reductase -2.3639
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D -2.363
MED17 mediator complex subunit 17 -2.36111
DKC1 dyskeratosis congenita 1, dyskerin -2.36075
ECT2 epithelial cell transforming 2 -2.35868
FFAR2 free fatty acid receptor 2 -2.35794
NEK4 NIMA-related kinase 4 -2.3579
RPL35 ribosomal protein L35 -2.3538
GABPA GA binding protein transcription factor, alpha subunit 60kDa -2.35311
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa -2.35237
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) -2.35118
CKS2 CDC28 protein kinase regulatory subunit 2 -2.34916
IPO4 importin 4 -2.3403
CDT1 chromatin licensing and DNA replication factor 1 -2.34006
GUF1 GUF1 GTPase homolog (S. cerevisiae) -2.33493
LYRM4 LYR motif containing 4 -2.33464
GPATCH1 G patch domain containing 1 -2.33251
ING1 inhibitor of growth family, member 1 -2.33188
MRFAP1L1 Morf4 family associated protein 1-like 1 -2.32637
LYRM2 LYR motif containing 2 -2.32526
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -2.32434
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -2.32308
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 -2.32117
CENPM centromere protein M -2.31651
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor -2.31634
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase -2.31247
CARHSP1 calcium regulated heat stable protein 1, 24kDa -2.31175
AHCY adenosylhomocysteinase -2.31101
FANCA Fanconi anemia, complementation group A -2.30881
RFC4 replication factor C (activator 1) 4, 37kDa -2.30706
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 -2.30402
GALK1 galactokinase 1 -2.30262
TRDMT1 tRNA aspartic acid methyltransferase 1 -2.30011
PROSER1 proline and serine rich 1 -2.30007
FRS2 fibroblast growth factor receptor substrate 2 -2.29961
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase -2.29855
GLDC glycine dehydrogenase (decarboxylating) -2.29711
MRPS33 mitochondrial ribosomal protein S33 -2.29711
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 -2.29694
PPP1R8 protein phosphatase 1, regulatory subunit 8 -2.29473
ENOSF1 enolase superfamily member 1 -2.29381
NUP107 nucleoporin 107kDa -2.29139
FOXM1 forkhead box M1 -2.29136
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -2.29111
IGFBP4 insulin-like growth factor binding protein 4 -2.29086
TMPO thymopoietin -2.29071
RANBP6 RAN binding protein 6 -2.2906
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha -2.28987
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -2.28981
RBBP4 retinoblastoma binding protein 4 -2.28856
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.28853
SPC25 SPC25, NDC80 kinetochore complex component -2.28623
HELLS helicase, lymphoid-specific -2.28385
PIPOX pipecolic acid oxidase -2.2828
NUP62 nucleoporin 62kDa -2.28027
MRS2 MRS2 magnesium transporter -2.27981
SLC35H1 solute carrier family 35 member H1 -2.27768
DBR1 debranching RNA lariats 1 -2.27723
GGNBP2 gametogenetin binding protein 2 -2.27678
MDC1 mediator of DNA-damage checkpoint 1 -2.27662
JARID2 jumonji, AT rich interactive domain 2 -2.27559
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 -2.27357
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) -2.27309
COIL coilin -2.27199
ZNF281 zinc finger protein 281 -2.26911
RANBP9 RAN binding protein 9 -2.26568
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) -2.25742
PTPRG protein tyrosine phosphatase, receptor type, G -2.25723
SPPL2A signal peptide peptidase like 2A -2.25676
GRB2 growth factor receptor-bound protein 2 -2.25562
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 -2.25421
CAND1 cullin-associated and neddylation-dissociated 1 -2.25354
TMEM267 transmembrane protein 267 -2.25172
CEP85 centrosomal protein 85kDa -2.2504
NCOA3 nuclear receptor coactivator 3 -2.24771
FERMT2 fermitin family member 2 -2.24751
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa -2.2454
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -2.24478
CBX1 chromobox homolog 1 -2.24235
ATP5MC1 ATP synthase membrane subunit c locus 1 -2.24223
CALCA calcitonin-related polypeptide alpha -2.24188
SNRPA small nuclear ribonucleoprotein polypeptide A -2.24178
AUNIP aurora kinase A and ninein interacting protein -2.24117
ANKRD17 ankyrin repeat domain 17 -2.24029
USP11 ubiquitin specific peptidase 11 -2.23908
C8A complement component 8, alpha polypeptide -2.23255
RHOH ras homolog family member H -2.232
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G -2.23112
MAGEA12 melanoma antigen family A12 -2.22931
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit -2.22526
DCTN5 dynactin 5 (p25) -2.22485
HOOK1 hook microtubule-tethering protein 1 -2.22357
MRPL35 mitochondrial ribosomal protein L35 -2.22353
HSF2 heat shock transcription factor 2 -2.22196
EML4 echinoderm microtubule associated protein like 4 -2.21761
SSR1 signal sequence receptor, alpha -2.2176
TLE3 transducin-like enhancer of split 3 -2.2168
CNTRL centriolin -2.2157
MIS12 MIS12 kinetochore complex component -2.21449
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa -2.21436
TIMELESS timeless circadian clock -2.21412
DSCC1 DNA replication and sister chromatid cohesion 1 -2.21408
CTPS2 CTP synthase 2 -2.21367
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa -2.21329
MRPS2 mitochondrial ribosomal protein S2 -2.21213
NUP98 nucleoporin 98kDa -2.21166
PBK PDZ binding kinase -2.21163
TACC3 transforming, acidic coiled-coil containing protein 3 -2.21114
SERBP1 SERPINE1 mRNA binding protein 1 -2.21072
SET SET nuclear proto-oncogene -2.2107
SRSF1 serine/arginine-rich splicing factor 1 -2.20669
RCN3 reticulocalbin 3, EF-hand calcium binding domain -2.20648
QSER1 glutamine and serine rich 1 -2.20611
MRPS18B mitochondrial ribosomal protein S18B -2.20572
WAPL WAPL cohesin release factor -2.20453
ZWINT ZW10 interacting kinetochore protein -2.20286
EIF3E eukaryotic translation initiation factor 3, subunit E -2.20055
ST20-MTHFS ST20-MTHFS readthrough -2.1995
MRPS27 mitochondrial ribosomal protein S27 -2.19837
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD) -2.19803
CALML4 calmodulin-like 4 -2.19794
NONO non-POU domain containing, octamer-binding -2.19542
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -2.19341
PTGES3 prostaglandin E synthase 3 (cytosolic) -2.1922
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent -2.19113
SPRY2 sprouty homolog 2 (Drosophila) -2.18973
KANSL1 KAT8 regulatory NSL complex subunit 1 -2.1896
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -2.18883
UIMC1 ubiquitin interaction motif containing 1 -2.18837
PLAG1 pleiomorphic adenoma gene 1 -2.18803
KIN Kin17 DNA and RNA binding protein -2.18096
TMF1 TATA element modulatory factor 1 -2.18066
FNBP4 formin binding protein 4 -2.17999
FBXL4 F-box and leucine-rich repeat protein 4 -2.17954
MNS1 meiosis-specific nuclear structural 1 -2.17809
METTL18 methyltransferase like 18 -2.17564
PGAP2 post-GPI attachment to proteins 2 -2.17239
SRBD1 S1 RNA binding domain 1 -2.17232
ANAPC1 anaphase promoting complex subunit 1 -2.17027
PALB2 partner and localizer of BRCA2 -2.16815
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 -2.16793
LRP5 low density lipoprotein receptor-related protein 5 -2.1678
NCAPD3 non-SMC condensin II complex, subunit D3 -2.16685
NOL8 nucleolar protein 8 -2.16527
PAGR1 PAXIP1 associated glutamate-rich protein 1 -2.16178
CHSY1 chondroitin sulfate synthase 1 -2.1617
DCP2 decapping mRNA 2 -2.16029
MSH3 mutS homolog 3 -2.15726
ATAD5 ATPase family, AAA domain containing 5 -2.15617
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 -2.15534
PPIG peptidylprolyl isomerase G (cyclophilin G) -2.15359
PUS1 pseudouridylate synthase 1 -2.15331
FZD7 frizzled class receptor 7 -2.15056
KIF20B kinesin family member 20B -2.15037
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin -2.14995
SOBP sine oculis binding protein homolog (Drosophila) -2.14701
CCDC59 coiled-coil domain containing 59 -2.14517
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.14511
FUS FUS RNA binding protein -2.14471
CEP57 centrosomal protein 57kDa -2.14383
SELENOT selenoprotein T -2.14188
ACTG1 actin gamma 1 -2.13917
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.13824
ATG5 autophagy related 5 -2.13696
KLHL26 kelch-like family member 26 -2.1363
NNT nicotinamide nucleotide transhydrogenase -2.13567
SETX senataxin -2.13541
CEP170 centrosomal protein 170kDa -2.13465
GID8 GID complex subunit 8 -2.13444
ASB7 ankyrin repeat and SOCS box containing 7 -2.1334
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -2.13152
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 -2.13072
API5 apoptosis inhibitor 5 -2.12872
LYSET lysosomal enzyme trafficking factor -2.1283
PNISR PNN-interacting serine/arginine-rich protein -2.12157
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase -2.12156
F7 coagulation factor VII (serum prothrombin conversion accelerator) -2.12038
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -2.11979
VAV3 vav 3 guanine nucleotide exchange factor -2.11927
ANKH ANKH inorganic pyrophosphate transport regulator -2.11871
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 -2.11864
CD247 CD247 molecule -2.1171
PRELID3A PRELI domain containing 3A -2.11391
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 -2.11318
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae) -2.11196
SCFD1 sec1 family domain containing 1 -2.11129
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -2.11041
TUBD1 tubulin, delta 1 -2.10724
RCC1 regulator of chromosome condensation 1 -2.10659
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 -2.10641
PPP6C protein phosphatase 6, catalytic subunit -2.10599
TUBB4B tubulin, beta 4B class IVb -2.1041
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -2.10332
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -2.10322
COMMD3-BMI1 COMMD3-BMI1 readthrough -2.10241
CCDC88C coiled-coil domain containing 88C -2.10177
RBM4 RNA binding motif protein 4 -2.10084
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -2.09957
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 -2.09838
EMILIN1 elastin microfibril interfacer 1 -2.09615
TRIM9 tripartite motif containing 9 -2.09502
YAP1 Yes-associated protein 1 -2.0936
PRKDC protein kinase, DNA-activated, catalytic polypeptide -2.0922
IFT88 intraflagellar transport 88 -2.09147
TMEM33 transmembrane protein 33 -2.08671
CTPS1 CTP synthase 1 -2.08646
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein -2.08558
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) -2.08359
CPB2 carboxypeptidase B2 (plasma) -2.08239
ZNF672 zinc finger protein 672 -2.08215
NUP155 nucleoporin 155kDa -2.08195
ARMCX5 armadillo repeat containing, X-linked 5 -2.08171
FAM216A family with sequence similarity 216, member A -2.08134
NUP205 nucleoporin 205kDa -2.0812
STIL SCL/TAL1 interrupting locus -2.08051
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 -2.08007
CCDC15 coiled-coil domain containing 15 -2.08003
UNG uracil-DNA glycosylase -2.07822
RAB27A RAB27A, member RAS oncogene family -2.07734
PROX1 prospero homeobox 1 -2.0768
THOC1 THO complex 1 -2.07617
SMC5 structural maintenance of chromosomes 5 -2.0734
ABHD17B abhydrolase domain containing 17B -2.07257
NUP88 nucleoporin 88kDa -2.07212
PDS5B PDS5 cohesin associated factor B -2.07133
SFMBT1 Scm-like with four mbt domains 1 -2.07108
TADA2A transcriptional adaptor 2A -2.06599
RPH3A rabphilin 3A -2.06391
PAAF1 proteasomal ATPase-associated factor 1 -2.06322
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -2.06261
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) -2.06117
MCRS1 microspherule protein 1 -2.06082
STAT5B signal transducer and activator of transcription 5B -2.05949
ESRP2 epithelial splicing regulatory protein 2 -2.05852
SACS sacsin molecular chaperone -2.05814
MAPK13 mitogen-activated protein kinase 13 -2.05718
SIX1 SIX homeobox 1 -2.05716
ARPP19 cAMP-regulated phosphoprotein, 19kDa -2.05709
INPP5F inositol polyphosphate-5-phosphatase F -2.05593
FAM20B family with sequence similarity 20, member B -2.05552
POU2AF1 POU class 2 associating factor 1 -2.05384
CCT8 chaperonin containing TCP1, subunit 8 (theta) -2.05379
MARCKSL1 MARCKS-like 1 -2.05269
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 -2.05257
THUMPD1 THUMP domain containing 1 -2.05245
CCL16 chemokine (C-C motif) ligand 16 -2.05189
SMIM8 small integral membrane protein 8 -2.05086
TF transferrin -2.05046
CRLF1 cytokine receptor-like factor 1 -2.04965
ARHGAP19 Rho GTPase activating protein 19 -2.04915
SETD6 SET domain containing 6 -2.04382
ZNF518A zinc finger protein 518A -2.04346
KAT8 K(lysine) acetyltransferase 8 -2.04342
SHTN1 shootin 1 -2.04206
TBCE tubulin folding cofactor E -2.04093
SRP72 signal recognition particle 72kDa -2.03983
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 -2.03902
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta -2.03858
RANBP2 RAN binding protein 2 -2.03738
TMEM258 transmembrane protein 258 -2.03639
CDR2 cerebellar degeneration-related protein 2, 62kDa -2.03637
ALG8 ALG8, alpha-1,3-glucosyltransferase -2.03486
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) -2.03315
HNRNPM heterogeneous nuclear ribonucleoprotein M -2.03273
PARP1 poly (ADP-ribose) polymerase 1 -2.03242
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -2.03216
CHD1 chromodomain helicase DNA binding protein 1 -2.03189
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 -2.03092
PNO1 partner of NOB1 homolog (S. cerevisiae) -2.0296
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa -2.02911
MRPL39 mitochondrial ribosomal protein L39 -2.02866
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2 -2.02857
ZNF106 zinc finger protein 106 -2.02378
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 -2.02317
GPN3 GPN-loop GTPase 3 -2.0228
WAC WW domain containing adaptor with coiled-coil -2.02071
CNOT9 CCR4-NOT transcription complex subunit 9 -2.01973
ABI2 abl-interactor 2 -2.01957
SLC31A1 solute carrier family 31 (copper transporter), member 1 -2.01892
PCYOX1 prenylcysteine oxidase 1 -2.01859
PSRC1 proline/serine-rich coiled-coil 1 -2.01852
NDC1 NDC1 transmembrane nucleoporin -2.01733
ZMYND11 zinc finger, MYND-type containing 11 -2.01708
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A -2.0153
PARPBP PARP1 binding protein -2.01498
HAPSTR1 HUWE1 associated protein modifying stress responses -2.01315
ECHDC1 ethylmalonyl-CoA decarboxylase 1 -2.01012
PRMT3 protein arginine methyltransferase 3 -2.00853
TMEM168 transmembrane protein 168 -2.00518
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 -2.00395
DENND1C DENN/MADD domain containing 1C -2.00367
NFYA nuclear transcription factor Y, alpha -2.00314
TDRD3 tudor domain containing 3 -2.00149
CFAP20 cilia and flagella associated protein 20 -2.00035