CRCGN015_HEPG2_48H:C04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tranilast 100.0 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN015_HEPG2_48H:C04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
KHDC4 KH domain containing 4, pre-mRNA splicing factor 2.68299
BAD BCL2-associated agonist of cell death 2.62743
TEX10 testis expressed 10 2.28039
EFR3A EFR3 homolog A (S. cerevisiae) 2.21026
EAPP E2F-associated phosphoprotein 2.11788
SCYL3 SCY1-like 3 (S. cerevisiae) 2.10684
LOC128125814 uncharacterized LOC128125814 2.08572
TRIB3 tribbles pseudokinase 3 2.07995
SAP130 Sin3A-associated protein, 130kDa 2.07088
ZNHIT3 zinc finger, HIT-type containing 3 2.04542

decreased expression

Symbol Name Standardized Value
CXADR coxsackie virus and adenovirus receptor -4.75877
CRK v-crk avian sarcoma virus CT10 oncogene homolog -4.2066
PDLIM1 PDZ and LIM domain 1 -3.75646
MT1X metallothionein 1X -3.53711
MRPS16 mitochondrial ribosomal protein S16 -3.10998
EIF3I eukaryotic translation initiation factor 3, subunit I -2.75848
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 -2.34711
FAIM Fas apoptotic inhibitory molecule -2.34473
S100P S100 calcium binding protein P -2.3388
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -2.32778
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 -2.19017
BMP4 bone morphogenetic protein 4 -2.07691
GID4 GID complex subunit 4 -2.03825