CRCGN015_HEPG2_48H:C06 Gene Set
Genes
27 genes differentially expressed following the CRCGN015_HEPG2_48H:C06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
3.46872
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.45464
|
|
UBE2A
|
ubiquitin-conjugating enzyme E2A
|
3.01228
|
|
MCOLN1
|
mucolipin 1
|
2.97402
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.70357
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.66911
|
|
CWF19L1
|
CWF19-like 1, cell cycle control (S. pombe)
|
2.46119
|
|
GSDMD
|
gasdermin D
|
2.23031
|
|
LIMD1
|
LIM domains containing 1
|
2.14109
|
|
COMMD3-BMI1
|
COMMD3-BMI1 readthrough
|
2.1038
|
|
EDAR
|
ectodysplasin A receptor
|
2.06908
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
2.01703
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
NME1
|
NME/NM23 nucleoside diphosphate kinase 1
|
-3.8569
|
|
MT1X
|
metallothionein 1X
|
-3.21723
|
|
AKR7A3
|
aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
|
-3.15951
|
|
CCDC86
|
coiled-coil domain containing 86
|
-3.06577
|
|
COTL1
|
coactosin-like F-actin binding protein 1
|
-2.8686
|
|
AKR7A2
|
aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
|
-2.86079
|
|
TFRC
|
transferrin receptor
|
-2.58354
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.37474
|
|
SPIB
|
Spi-B transcription factor (Spi-1/PU.1 related)
|
-2.30832
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
-2.27328
|
|
TXNRD1
|
thioredoxin reductase 1
|
-2.16706
|
|
SRD5A1
|
steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
|
-2.16393
|
|
SERGEF
|
secretion regulating guanine nucleotide exchange factor
|
-2.08429
|
|
CLEC7A
|
C-type lectin domain family 7, member A
|
-2.05447
|
|
PRKAR2B
|
protein kinase, cAMP-dependent, regulatory, type II, beta
|
-2.01487
|
