| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 15-delta-prostaglandin-j2 2.0 um perturbation at 48 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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74 genes differentially expressed following the CRCGN015_HEPG2_48H:C07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 4.36251 |
| HMOX1 | heme oxygenase 1 | 4.13046 |
| ABHD4 | abhydrolase domain containing 4 | 3.46971 |
| TXNRD1 | thioredoxin reductase 1 | 3.46144 |
| SQSTM1 | sequestosome 1 | 3.2451 |
| ANO10 | anoctamin 10 | 2.82271 |
| CTSL | cathepsin L | 2.6579 |
| PRKCQ | protein kinase C, theta | 2.65601 |
| SCAND1 | SCAN domain containing 1 | 2.62951 |
| C1QBP | complement component 1, q subcomponent binding protein | 2.58454 |
| CDC123 | cell division cycle 123 | 2.57083 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 2.56446 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 2.54041 |
| IER3 | immediate early response 3 | 2.48528 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 2.46812 |
| HYOU1 | hypoxia up-regulated 1 | 2.43351 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 2.42382 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 2.38874 |
| MRPS22 | mitochondrial ribosomal protein S22 | 2.36049 |
| HSPA14 | heat shock 70kDa protein 14 | 2.35048 |
| GRPEL1 | GrpE-like 1, mitochondrial (E. coli) | 2.26684 |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) | 2.21976 |
| BCL3 | B-cell CLL/lymphoma 3 | 2.19107 |
| NSMAF | neutral sphingomyelinase (N-SMase) activation associated factor | 2.18033 |
| TEX10 | testis expressed 10 | 2.13731 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 2.13651 |
| CSF1R | colony stimulating factor 1 receptor | 2.13609 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 2.1249 |
| PANK2 | pantothenate kinase 2 | 2.1049 |
| UGDH | UDP-glucose 6-dehydrogenase | 2.10418 |
| EPN2 | epsin 2 | 2.07725 |
| EMC7 | ER membrane protein complex subunit 7 | 2.07311 |
| PCDHB11 | protocadherin beta 11 | 2.06036 |
| BYSL | bystin-like | 2.03752 |
| KEAP1 | kelch-like ECH-associated protein 1 | 2.0368 |
| DLAT | dihydrolipoamide S-acetyltransferase | 2.03038 |
| FASTKD5 | FAST kinase domains 5 | 2.02337 |
| POLR1G | RNA polymerase I subunit G | 2.01016 |
| PSMD13 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 | 2.00714 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA8 | heat shock 70kDa protein 8 | -3.97583 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -3.68442 |
| CXADR | coxsackie virus and adenovirus receptor | -3.35556 |
| CD58 | CD58 molecule | -3.02931 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -2.88594 |
| PPP1R26 | protein phosphatase 1, regulatory subunit 26 | -2.86889 |
| HLA-G | major histocompatibility complex, class I, G | -2.84605 |
| DPYSL2 | dihydropyrimidinase-like 2 | -2.83353 |
| CBR4 | carbonyl reductase 4 | -2.58154 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | -2.56108 |
| HLA-F | major histocompatibility complex, class I, F | -2.49218 |
| KLHDC2 | kelch domain containing 2 | -2.47633 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -2.43627 |
| PBLD | phenazine biosynthesis-like protein domain containing | -2.409 |
| SLC35E2B | solute carrier family 35, member E2B | -2.38757 |
| RHOB | ras homolog family member B | -2.3688 |
| SLC38A2 | solute carrier family 38, member 2 | -2.28 |
| ANXA4 | annexin A4 | -2.26761 |
| PYGL | phosphorylase, glycogen, liver | -2.26445 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | -2.24045 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -2.22176 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -2.2054 |
| C5 | complement component 5 | -2.18372 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -2.16021 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | -2.15418 |
| PIGV | phosphatidylinositol glycan anchor biosynthesis, class V | -2.11176 |
| NBPF19 | neuroblastoma breakpoint family, member 19 | -2.10851 |
| ZMYM3 | zinc finger, MYM-type 3 | -2.10122 |
| ANAPC2 | anaphase promoting complex subunit 2 | -2.0831 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | -2.07952 |
| CELSR2 | cadherin, EGF LAG seven-pass G-type receptor 2 | -2.07789 |
| PLXNB2 | plexin B2 | -2.04737 |
| COPS7B | COP9 signalosome subunit 7B | -2.03819 |
| HMGN3 | high mobility group nucleosomal binding domain 3 | -2.03084 |
| CCNG2 | cyclin G2 | -2.01566 |
