CRCGN015_HEPG2_48H:C10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description cimetidine 99.96 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

10 genes differentially expressed following the CRCGN015_HEPG2_48H:C10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDC25A cell division cycle 25A 2.91259
FPGS folylpolyglutamate synthase 2.90022
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 2.65725
KIFBP kinesin family binding protein 2.26875

decreased expression

Symbol Name Standardized Value
PDLIM1 PDZ and LIM domain 1 -5.17567
MAPK13 mitogen-activated protein kinase 13 -3.62552
FBXL12 F-box and leucine-rich repeat protein 12 -2.51002
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.47763
LOC124907782 dual specificity protein phosphatase 22 -2.18279
ZBTB35 zinc finger and BTB domain containing 35 -2.1636