CRCGN015_HEPG2_48H:C12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description cimetidine 11.11 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

11 genes differentially expressed following the CRCGN015_HEPG2_48H:C12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GABPB1 GA binding protein transcription factor, beta subunit 1 3.13034
ADO 2-aminoethanethiol (cysteamine) dioxygenase 2.90446
DENND2D DENN/MADD domain containing 2D 2.67915
TNIP1 TNFAIP3 interacting protein 1 2.59669
IRF8 interferon regulatory factor 8 2.08795
PEX11A peroxisomal biogenesis factor 11 alpha 2.02312

decreased expression

Symbol Name Standardized Value
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -3.68486
BIRC2 baculoviral IAP repeat containing 2 -2.55504
HEBP1 heme binding protein 1 -2.5273
RHOB ras homolog family member B -2.33743
EN2 engrailed homeobox 2 -2.08094