CRCGN015_HEPG2_48H:C15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description oxyquinoline 11.27 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

24 genes differentially expressed following the CRCGN015_HEPG2_48H:C15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
EPHB2 EPH receptor B2 5.03036
CDX1 caudal type homeobox 1 2.48801
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 2.47105
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 2.4485
GUCY2C guanylate cyclase 2C 2.29903
DEFA6 defensin, alpha 6, Paneth cell-specific 2.25684
PPA2 pyrophosphatase (inorganic) 2 2.13212

decreased expression

Symbol Name Standardized Value
CXADR coxsackie virus and adenovirus receptor -7.21725
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -4.572
COG7 component of oligomeric golgi complex 7 -4.25933
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -4.23359
FBXL12 F-box and leucine-rich repeat protein 12 -4.20693
TM9SF3 transmembrane 9 superfamily member 3 -3.55411
MT1X metallothionein 1X -2.98487
KIF20A kinesin family member 20A -2.66074
CSRP2 cysteine and glycine-rich protein 2 -2.59929
ANXA10 annexin A10 -2.45091
MARK1 MAP/microtubule affinity-regulating kinase 1 -2.19287
TOP2A topoisomerase (DNA) II alpha 170kDa -2.11588
LITAF lipopolysaccharide-induced TNF factor -2.08367
TMSB10 thymosin beta 10 -2.07364
SYT17 synaptotagmin XVII -2.04849
OSBPL10 oxysterol binding protein-like 10 -2.04761
SYP synaptophysin -2.00556