CRCGN015_HEPG2_48H:C16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1-nitronaphthalene 100.97 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN015_HEPG2_48H:C16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SMIM40 small integral membrane protein 40 4.85803
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 3.84158
EVL Enah/Vasp-like 2.53113
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 2.43114
GATA2 GATA binding protein 2 2.40662
UBXN8 UBX domain protein 8 2.06715
ADRA2A adrenoceptor alpha 2A 2.03055

decreased expression

Symbol Name Standardized Value
DHRS7 dehydrogenase/reductase (SDR family) member 7 -5.16364
STAT1 signal transducer and activator of transcription 1, 91kDa -3.50204
MRPS16 mitochondrial ribosomal protein S16 -3.18476
PROM1 prominin 1 -2.47793
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -2.44917
ISG15 ISG15 ubiquitin-like modifier -2.22509
CLTCL1 clathrin, heavy chain-like 1 -2.17336
BAZ2B bromodomain adjacent to zinc finger domain, 2B -2.15945
IFI6 interferon, alpha-inducible protein 6 -2.07478
IRF9 interferon regulatory factor 9 -2.07169