CRCGN015_HEPG2_48H:C17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1-nitronaphthalene 33.66 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

12 genes differentially expressed following the CRCGN015_HEPG2_48H:C17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SNX11 sorting nexin 11 2.9049
MAMLD1 mastermind-like domain containing 1 2.77343
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 2.4991
CBX1 chromobox homolog 1 2.20832
SLC75A1 solute carrier family 75 member 1 2.01366

decreased expression

Symbol Name Standardized Value
EIF5 eukaryotic translation initiation factor 5 -3.24634
PCCB propionyl CoA carboxylase, beta polypeptide -3.0404
SLC35F2 solute carrier family 35, member F2 -2.65426
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -2.36428
BAX BCL2-associated X protein -2.24271
UBE2H ubiquitin-conjugating enzyme E2H -2.07466
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.02371