CRCGN015_HEPG2_48H:C18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1-nitronaphthalene 11.22 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN015_HEPG2_48H:C18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.33918
SCRN1 secernin 1 2.67846
GAPDH glyceraldehyde-3-phosphate dehydrogenase 2.50831
RPL8 ribosomal protein L8 2.47953
RPS19 ribosomal protein S19 2.37616
PABPC3 poly(A) binding protein, cytoplasmic 3 2.23596
RPL12 ribosomal protein L12 2.22368
RPS11 ribosomal protein S11 2.19159
PABPC1 poly(A) binding protein, cytoplasmic 1 2.18724
COQ8A coenzyme Q8A 2.16342
ZFP36 ZFP36 ring finger protein 2.14647
RPL18 ribosomal protein L18 2.09879
RPL4 ribosomal protein L4 2.0879
COMMD1 copper metabolism (Murr1) domain containing 1 2.08543

decreased expression

Symbol Name Standardized Value
BIRC2 baculoviral IAP repeat containing 2 -3.61651
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -3.46312
PDLIM1 PDZ and LIM domain 1 -2.59242
CXADR coxsackie virus and adenovirus receptor -2.49741
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -2.46231
MT1X metallothionein 1X -2.16759
BIRC3 baculoviral IAP repeat containing 3 -2.02797