CRCGN015_HEPG2_48H:D01 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description serotonin 100.0 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

28 genes differentially expressed following the CRCGN015_HEPG2_48H:D01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MCOLN1 mucolipin 1 5.29612
HDGFL3 HDGF like 3 3.48246
NUCB2 nucleobindin 2 3.00715
PNPLA6 patatin-like phospholipase domain containing 6 2.82617
CBR1 carbonyl reductase 1 2.60071
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.53407
QTRT2 queuine tRNA-ribosyltransferase accessory subunit 2 2.39903
UGDH UDP-glucose 6-dehydrogenase 2.19687
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 2.16041
SLC61A1 solute carrier family 61 member 1 2.12164
PGC progastricsin (pepsinogen C) 2.02654
TMEM109 transmembrane protein 109 2.00095

decreased expression

Symbol Name Standardized Value
MT1X metallothionein 1X -3.63109
PROM1 prominin 1 -3.15949
RBM34 RNA binding motif protein 34 -3.10381
CXADR coxsackie virus and adenovirus receptor -2.97665
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -2.62008
GGPS1 geranylgeranyl diphosphate synthase 1 -2.4459
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -2.22108
ACTR6 ARP6 actin-related protein 6 homolog (yeast) -2.20655
AMBN ameloblastin (enamel matrix protein) -2.1974
FAIM Fas apoptotic inhibitory molecule -2.19167
TEX14 testis expressed 14 -2.15737
CCDC90B coiled-coil domain containing 90B -2.12752
SAP30BP SAP30 binding protein -2.11956
METTL18 methyltransferase like 18 -2.04518
GBP2 guanylate binding protein 2, interferon-inducible -2.03669
EIF3H eukaryotic translation initiation factor 3, subunit H -2.02053