CRCGN015_HEPG2_48H:D04 Gene Set
Genes
51 genes differentially expressed following the CRCGN015_HEPG2_48H:D04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
TRIB3
|
tribbles pseudokinase 3
|
3.8488
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
3.33804
|
|
PRR15L
|
proline rich 15-like
|
3.11799
|
|
MTHFD2
|
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
|
3.11364
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
3.07622
|
|
SLC75A1
|
solute carrier family 75 member 1
|
2.82994
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
2.81194
|
|
ASNS
|
asparagine synthetase (glutamine-hydrolyzing)
|
2.76487
|
|
USP6NL
|
USP6 N-terminal like
|
2.69419
|
|
YARS1
|
tyrosyl-tRNA synthetase 1
|
2.61964
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
2.47396
|
|
FHL2
|
four and a half LIM domains 2
|
2.44277
|
|
VAT1
|
vesicle amine transport 1
|
2.44022
|
|
TLCD3A
|
TLC domain containing 3A
|
2.40927
|
|
ARHGEF2
|
Rho/Rac guanine nucleotide exchange factor (GEF) 2
|
2.30217
|
|
SQSTM1
|
sequestosome 1
|
2.29962
|
|
EIF4EBP1
|
eukaryotic translation initiation factor 4E binding protein 1
|
2.2747
|
|
NANOS3
|
nanos homolog 3 (Drosophila)
|
2.23673
|
|
RUVBL1
|
RuvB-like AAA ATPase 1
|
2.23627
|
|
ACLY
|
ATP citrate lyase
|
2.2329
|
|
PHC2
|
polyhomeotic homolog 2 (Drosophila)
|
2.22124
|
|
CLNS1A
|
chloride channel, nucleotide-sensitive, 1A
|
2.18349
|
|
NETO2
|
neuropilin (NRP) and tolloid (TLL)-like 2
|
2.18308
|
|
CHI3L1
|
chitinase 3-like 1 (cartilage glycoprotein-39)
|
2.15211
|
|
INPP1
|
inositol polyphosphate-1-phosphatase
|
2.11456
|
|
LYRM1
|
LYR motif containing 1
|
2.10854
|
|
PKN1
|
protein kinase N1
|
2.10042
|
|
SARS1
|
seryl-tRNA synthetase 1
|
2.0712
|
|
EREG
|
epiregulin
|
2.05829
|
|
ZFP36
|
ZFP36 ring finger protein
|
2.05699
|
|
BLVRA
|
biliverdin reductase A
|
2.00432
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PSMD10
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
|
-3.79593
|
|
SESN1
|
sestrin 1
|
-2.94782
|
|
KIF20A
|
kinesin family member 20A
|
-2.52814
|
|
DNAJB2
|
DnaJ (Hsp40) homolog, subfamily B, member 2
|
-2.44344
|
|
STMN1
|
stathmin 1
|
-2.41795
|
|
ASPM
|
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
|
-2.38409
|
|
CENPE
|
centromere protein E, 312kDa
|
-2.34733
|
|
ZBTB35
|
zinc finger and BTB domain containing 35
|
-2.32277
|
|
BIRC5
|
baculoviral IAP repeat containing 5
|
-2.23562
|
|
PUS3
|
pseudouridylate synthase 3
|
-2.18984
|
|
HELZ
|
helicase with zinc finger
|
-2.1801
|
|
DDB2
|
damage-specific DNA binding protein 2, 48kDa
|
-2.17545
|
|
TOP2A
|
topoisomerase (DNA) II alpha 170kDa
|
-2.16479
|
|
B4GAT1
|
beta-1,4-glucuronyltransferase 1
|
-2.12016
|
|
BAX
|
BCL2-associated X protein
|
-2.09562
|
|
KLHDC2
|
kelch domain containing 2
|
-2.0916
|
|
INSIG1
|
insulin induced gene 1
|
-2.08667
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
-2.06327
|
|
NUSAP1
|
nucleolar and spindle associated protein 1
|
-2.02648
|
|
PDLIM1
|
PDZ and LIM domain 1
|
-2.01775
|
