CRCGN015_HEPG2_48H:D07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,4-dinitrotoluene 99.96 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

16 genes differentially expressed following the CRCGN015_HEPG2_48H:D07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RFC2 replication factor C (activator 1) 2, 40kDa 4.17777
BAD BCL2-associated agonist of cell death 3.78026
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 2.37674
RNPS1 RNA binding protein S1, serine-rich domain 2.17863
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) 2.06407
GAPDH glyceraldehyde-3-phosphate dehydrogenase 2.01866
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 2.00644

decreased expression

Symbol Name Standardized Value
ITFG1 integrin alpha FG-GAP repeat containing 1 -5.437
MAPK13 mitogen-activated protein kinase 13 -4.55433
RHOB ras homolog family member B -4.36641
CXADR coxsackie virus and adenovirus receptor -3.48329
FBXO21 F-box protein 21 -3.47337
MT1X metallothionein 1X -2.48674
KIF20A kinesin family member 20A -2.21645
SESN1 sestrin 1 -2.11091
S100P S100 calcium binding protein P -2.04306