CRCGN015_HEPG2_48H:D10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description metronidazole 103.49 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

15 genes differentially expressed following the CRCGN015_HEPG2_48H:D10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
LAGE3 L antigen family, member 3 3.8477
TNIP1 TNFAIP3 interacting protein 1 3.29062
UBQLN2 ubiquilin 2 2.83887
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 2.8164
METRN meteorin, glial cell differentiation regulator 2.42357
SLC75A1 solute carrier family 75 member 1 2.22803
ADO 2-aminoethanethiol (cysteamine) dioxygenase 2.1618

decreased expression

Symbol Name Standardized Value
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -4.80025
TM9SF3 transmembrane 9 superfamily member 3 -3.97583
CXADR coxsackie virus and adenovirus receptor -3.96366
TUBB6 tubulin, beta 6 class V -3.8044
SNX7 sorting nexin 7 -3.78973
CD58 CD58 molecule -3.18711
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.94569
FOXJ3 forkhead box J3 -2.86134