CRCGN015_HEPG2_48H:D11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description metronidazole 34.5 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

9 genes differentially expressed following the CRCGN015_HEPG2_48H:D11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CBR3 carbonyl reductase 3 4.00348
DENND2D DENN/MADD domain containing 2D 3.00875
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.65984
JADE2 jade family PHD finger 2 2.39422
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 2.2817
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) 2.07917
PZP pregnancy-zone protein 2.05897
MAMLD1 mastermind-like domain containing 1 2.00821

decreased expression

Symbol Name Standardized Value
NPDC1 neural proliferation, differentiation and control, 1 -2.03391