CRCGN015_HEPG2_48H:D13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1,1,1-trichloroethane, technical grade 98.44 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

14 genes differentially expressed following the CRCGN015_HEPG2_48H:D13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ANO10 anoctamin 10 9.50755
SCRN1 secernin 1 4.78278
MYLK myosin light chain kinase 3.62865
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 2.5924
IGF1R insulin-like growth factor 1 receptor 2.08573
CHEK2 checkpoint kinase 2 2.08069

decreased expression

Symbol Name Standardized Value
DERA deoxyribose-phosphate aldolase (putative) -4.74975
RAI14 retinoic acid induced 14 -3.29051
FASTKD5 FAST kinase domains 5 -3.1783
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.98859
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.36644
FAIM Fas apoptotic inhibitory molecule -2.35042
ZDHHC11B zinc finger, DHHC-type containing 11B -2.17263
MT1X metallothionein 1X -2.04695