CRCGN015_HEPG2_48H:D14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1,1,1-trichloroethane, technical grade 32.81 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

15 genes differentially expressed following the CRCGN015_HEPG2_48H:D14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TLCD3A TLC domain containing 3A 2.31234
COPS7A COP9 signalosome subunit 7A 2.31081
GRB10 growth factor receptor-bound protein 10 2.20173
FPGS folylpolyglutamate synthase 2.17846
REV1 REV1, polymerase (DNA directed) 2.15591

decreased expression

Symbol Name Standardized Value
CCNB1 cyclin B1 -3.98852
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -3.6639
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -3.51544
RPA3 replication protein A3, 14kDa -3.44732
TM9SF3 transmembrane 9 superfamily member 3 -2.78314
SLC35F2 solute carrier family 35, member F2 -2.69162
NGRN neugrin, neurite outgrowth associated -2.66319
S100P S100 calcium binding protein P -2.3852
CXADR coxsackie virus and adenovirus receptor -2.26789
MT1X metallothionein 1X -2.1611