CRCGN015_HEPG2_48H:D15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1,1,1-trichloroethane, technical grade 10.94 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

12 genes differentially expressed following the CRCGN015_HEPG2_48H:D15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.67544
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 3.31002
CYB561 cytochrome b561 3.13519
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 2.72718
IGHMBP2 immunoglobulin mu binding protein 2 2.63094
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 2.63065
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 2.16293
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 2.14812
POPDC2 popeye domain containing 2 2.09888

decreased expression

Symbol Name Standardized Value
TM9SF3 transmembrane 9 superfamily member 3 -3.82654
CXADR coxsackie virus and adenovirus receptor -3.78884
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -2.14373