CRCGN015_HEPG2_48H:D16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-butyl chloride 102.99 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

45 genes differentially expressed following the CRCGN015_HEPG2_48H:D16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SMIM40 small integral membrane protein 40 4.56656
RNF5 ring finger protein 5, E3 ubiquitin protein ligase 2.31001
TBCB tubulin folding cofactor B 2.22597
MARCKSL1 MARCKS-like 1 2.1643
PMM2 phosphomannomutase 2 2.14983
DXO decapping exoribonuclease 2.13836
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 2.13276
MYL9 myosin, light chain 9, regulatory 2.09968
CMTR1 cap methyltransferase 1 2.08098
IFT52 intraflagellar transport 52 2.06888
ADRA2A adrenoceptor alpha 2A 2.06571
SMCO4 single-pass membrane protein with coiled-coil domains 4 2.05825
ABHD4 abhydrolase domain containing 4 2.05798
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 2.04952
SNRPC small nuclear ribonucleoprotein polypeptide C 2.03719

decreased expression

Symbol Name Standardized Value
MT1X metallothionein 1X -8.91609
TUBB6 tubulin, beta 6 class V -4.90027
GOLT1B golgi transport 1B -4.17401
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -4.10502
EIF5 eukaryotic translation initiation factor 5 -4.0882
TM9SF3 transmembrane 9 superfamily member 3 -3.34274
S100P S100 calcium binding protein P -3.11099
RECQL RecQ helicase-like -3.06272
CSRP2 cysteine and glycine-rich protein 2 -2.70365
DIPK1A divergent protein kinase domain 1A -2.6037
MT1E metallothionein 1E -2.57618
TFRC transferrin receptor -2.5563
MT1F metallothionein 1F -2.5483
MT1H metallothionein 1H -2.51495
MT1G metallothionein 1G -2.47353
MT2A metallothionein 2A -2.44485
LAPTM4A lysosomal protein transmembrane 4 alpha -2.36704
ND5 NADH dehydrogenase subunit 5 -2.31409
CXADR coxsackie virus and adenovirus receptor -2.31141
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -2.29
INTS13 integrator complex subunit 13 -2.22116
KRT7 keratin 7, type II -2.21599
ATG2B autophagy related 2B -2.20071
NMRK1 nicotinamide riboside kinase 1 -2.18314
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) -2.07295
BCAP29 B-cell receptor-associated protein 29 -2.06554
CLEC2D C-type lectin domain family 2, member D -2.06254
CYBRD1 cytochrome b reductase 1 -2.054
PLS1 plastin 1 -2.014
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein -2.00648