| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | coumophos 97.26 um perturbation at 48 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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50 genes differentially expressed following the CRCGN015_HEPG2_48H:D19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF586 | zinc finger protein 586 | 3.4353 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 3.37859 |
| TRIB3 | tribbles pseudokinase 3 | 3.1404 |
| DDIT4 | DNA-damage-inducible transcript 4 | 3.07876 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 2.66891 |
| NOTCH1 | notch 1 | 2.58391 |
| ZFP36 | ZFP36 ring finger protein | 2.54908 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | 2.40921 |
| CNPY3 | canopy FGF signaling regulator 3 | 2.38488 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 2.24465 |
| DENND4B | DENN/MADD domain containing 4B | 2.21779 |
| NANOS3 | nanos homolog 3 (Drosophila) | 2.1901 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 2.15797 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | 2.14968 |
| APOE | apolipoprotein E | 2.13117 |
| CRTAP | cartilage associated protein | 2.0636 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 2.06114 |
| SHMT2 | serine hydroxymethyltransferase 2 (mitochondrial) | 2.0377 |
| C5AR1 | complement component 5a receptor 1 | 2.03714 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 2.01075 |
| USP6NL | USP6 N-terminal like | 2.00517 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -7.45144 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -4.52111 |
| PUF60 | poly-U binding splicing factor 60KDa | -4.02741 |
| SLC52A2 | solute carrier family 52 (riboflavin transporter), member 2 | -2.72845 |
| KIF20A | kinesin family member 20A | -2.60574 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -2.57445 |
| BBS7 | Bardet-Biedl syndrome 7 | -2.49202 |
| CD58 | CD58 molecule | -2.46443 |
| MED31 | mediator complex subunit 31 | -2.43613 |
| FAIM | Fas apoptotic inhibitory molecule | -2.40461 |
| ZFP37 | ZFP37 zinc finger protein | -2.36281 |
| ZNF16 | zinc finger protein 16 | -2.34129 |
| CCNB1 | cyclin B1 | -2.32915 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -2.32417 |
| SRSF4 | serine/arginine-rich splicing factor 4 | -2.24181 |
| GPR52 | G protein-coupled receptor 52 | -2.20138 |
| PCYOX1 | prenylcysteine oxidase 1 | -2.16018 |
| OR7A5 | olfactory receptor, family 7, subfamily A, member 5 | -2.14276 |
| CLEC1A | C-type lectin domain family 1, member A | -2.13156 |
| HGH1 | HGH1 homolog (S. cerevisiae) | -2.11657 |
| PYCR3 | pyrroline-5-carboxylate reductase 3 | -2.08548 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -2.07878 |
| ZNF7 | zinc finger protein 7 | -2.06376 |
| RAB30 | RAB30, member RAS oncogene family | -2.05519 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -2.03258 |
| TSR2 | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) | -2.03098 |
| BIRC5 | baculoviral IAP repeat containing 5 | -2.02916 |
| ADPRH | ADP-ribosylarginine hydrolase | -2.01373 |
| BBS4 | Bardet-Biedl syndrome 4 | -2.00284 |
