CRCGN015_HEPG2_48H:D21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description coumophos 10.81 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

13 genes differentially expressed following the CRCGN015_HEPG2_48H:D21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HOXA10 homeobox A10 2.70531
TESK1 testis-specific kinase 1 2.44694
DDB2 damage-specific DNA binding protein 2, 48kDa 2.37991
HOXA10-HOXA9 HOXA10-HOXA9 readthrough 2.15268

decreased expression

Symbol Name Standardized Value
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -6.98935
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -4.68843
HPRT1 hypoxanthine phosphoribosyltransferase 1 -4.67759
UGDH UDP-glucose 6-dehydrogenase -2.85374
ATG4A autophagy related 4A, cysteine peptidase -2.67589
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -2.54206
MKNK1 MAP kinase interacting serine/threonine kinase 1 -2.51033
CXADR coxsackie virus and adenovirus receptor -2.22807
HEATR1 HEAT repeat containing 1 -2.11745