CRCGN015_HEPG2_48H:D23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n,n-dimethyl-n'-[3-(trifluoromethyl)phenyl]urea 32.18 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN015_HEPG2_48H:D23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
BAD BCL2-associated agonist of cell death 3.35418
SPAG4 sperm associated antigen 4 3.28377
CNPY3 canopy FGF signaling regulator 3 2.75831
CHMP6 charged multivesicular body protein 6 2.58144
COQ8A coenzyme Q8A 2.13258

decreased expression

Symbol Name Standardized Value
COG7 component of oligomeric golgi complex 7 -4.4013
BIRC2 baculoviral IAP repeat containing 2 -3.54304
NCK1 NCK adaptor protein 1 -3.19264
VAT1 vesicle amine transport 1 -3.19062
CXADR coxsackie virus and adenovirus receptor -2.91226
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -2.65351
MT1X metallothionein 1X -2.38497
NPIPA6 nuclear pore complex interacting protein family, member A6 -2.35621
FLCN folliculin -2.14707
CCDC30 coiled-coil domain containing 30 -2.01862
CLEC1A C-type lectin domain family 1, member A -2.01479
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae) -2.00799